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ClinicalTrials.gov public records Last synced Sep 30, 2026, 1:27 PM EDT

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Showing 1–24 of 91 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Osteopathic manipulative treatment (OMT) Clear all
Recruiting Not applicable Interventional

OPT-IN: Osteopathic Plagiocephaly Treatment for Infants and Neonates

NCT05848895
View directory record Official record
Conditions
Plagiocephaly, Nonsynostotic, Plagiocephaly, Positional, Plagiocephaly, Cranium; Deformity
Interventions
Osteopathic Manipulative Treatment, Standard of Care Repositioning
Procedure · Behavioral
Lead sponsor
Osteopathy's Promise to Children
Other
Eligibility
1 Day to 4 Months
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

By Potentially Adding a Century Old Therapeutic Measure to Pain Treatment Regimens Called Osteopathic Manipulative Treatment, Can Help Decrease Muscle and Bone Pain and the Usage of Opioid Pain Medication.

NCT06930196
View directory record Official record
Conditions
Osteopathic Manipulative Treatment
Interventions
Counterstrain, Muscle Energy, High Velocity Low Amplitude, The Ultralign SA201 used for measuring tissue texture changes, IsoTouch
Other · Device
Lead sponsor
Skagit Regional Health
Other
Eligibility
18 Years to 65 Years
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Augmentation of Immune Response to COVID-19 mRNA Vaccination Through OMT With Lymphatic Pumps

NCT04928456
View directory record Official record
Conditions
Covid19
Interventions
Osteopathic Manipulative Treatment (OMT)
Other
Lead sponsor
Western University of Health Sciences
Other
Eligibility
18 Years to 65 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2024 · Synced Sep 30, 2026, 1:27 PM EDT
Completed No phase listed Observational

Asthma and Osteopathic Manipulative Treatment

NCT03864354
View directory record Official record
Conditions
Asthma
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Des Moines University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Early Phase 1 Interventional

Hyperbaric Oxygen and Manipulative Therapies to Regain Function Post Stroke

NCT03352232
View directory record Official record
Conditions
Stroke, Motor Dysfunction, Chronic Stroke, Ischemic Stroke
Interventions
HBOT and OMT
Combination Product
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Abington, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 21, 2021 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Not applicable Interventional Results available

Osteopathic Otitis Media Research Study

NCT00520039
View directory record Official record
Conditions
Otitis Media With Effusion
Interventions
osteopathic manipulative medicine (OMM)
Procedure
Lead sponsor
West Virginia School of Osteopathic Medicine
Other
Eligibility
6 Months to 2 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Biddeford, Maine • Lewisburg, West Virginia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2018 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Pregnancy-Related Low Back Pain and Complementary and Alternative Medicine (CAM) Treatment

NCT00937365
View directory record Official record
Conditions
Low Back Pain
Interventions
Exercise, Spinal Manipulation, Neuroemotional Technique (NET)
Behavioral · Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
20 Years to 49 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Not applicable Interventional

Comparing the Effect of Osteopathic Manipulative Medicine (OMM) Versus Counseling in the Treatment of Concussion

NCT02750566
View directory record Official record
Conditions
Post-Concussion Symptoms, Distorted; Balance
Interventions
Osteopathic Manipulative Treatment, Counseling
Procedure · Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 50 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of OMT on Gait Kinematics and Postural Control in Parkinson Disease

NCT04946760
View directory record Official record
Conditions
Parkinson Disease
Interventions
Sham Manipulation
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
50 Years and older
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Sep 30, 2026, 1:27 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Osteopathic Manipulative Treatment in the Third Trimester of Pregnancy

NCT06570395
View directory record Official record
Conditions
Pregnancy, Osteopathic Manipulative Treatment (OMT)
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Corewell Health South
Other
Eligibility
18 Years to 34 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Saint Joseph, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Phase 3 Interventional Results available

Osteopathic Health Outcomes in Chronic Low Back Pain (OSTEOPATHIC) Trial

NCT00315120
View directory record Official record
Conditions
Low Back Pain
Interventions
A. Active OMT and active UST, B. Sham OMT and active UST, C. Active OMT and sham UST, D. Sham OMT and sham UST
Procedure
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
21 Years to 69 Years
Enrollment
455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 6, 2016 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Not applicable Interventional

Investigating the Efficacy of Osteopathic Manipulative Treatment on Gait Dysfunction Following Knee Surgery

NCT05580640
View directory record Official record
Conditions
Knee Arthroscopy, Knee Arthroplasty, Osteopathic Manipulative Treatment, Gait, Unsteady
Interventions
OMT
Procedure
Lead sponsor
Midwestern University
Other
Eligibility
21 Years to 90 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Downers Grove, Illinois
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Osteopathic Manipulative Treatment of Fascial Restrictions on Body Awareness, Mood, and Proprioception

NCT04945798
View directory record Official record
Conditions
Segmental and Somatic Dysfunction of Other Regions (M99.09)
Interventions
OMT
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Jonesboro, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 29, 2022 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Osteopathic Manipulative Treatment (OMT) on Proprioception in Adults

NCT04374227
View directory record Official record
Conditions
Osteopathy in Diseases Classified Elsewhere
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Des Moines University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated May 5, 2020 · Synced Sep 30, 2026, 1:27 PM EDT
Completed No phase listed Observational

Cost Effectiveness of OMT for Chronic Low Back Pain

NCT03532230
View directory record Official record
Conditions
Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb, Lesion of Sciatic Nerve, Right Lower Limb, Lumbar Spinal Stenosis, Lumbar Spondylosis, Lumbago With Sciatica, Left Side, Lumbago With Sciatica, Right Side
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 84 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
East Lansing, Michigan • Stratford, New Jersey • Voorhees Township, New Jersey
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Sep 30, 2026, 1:27 PM EDT
Not listed Not applicable Interventional

Effects of a Single Osteopathic Manipulative Treatment (OMT) on Intraocular Pressure (IOP) Reduction

NCT03590249
View directory record Official record
Conditions
Glaucoma
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Sep 30, 2026, 1:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating the Efficacy of OMT to Recover Olfactory Perception After COVID-19

NCT06766279
View directory record Official record
Conditions
Anosmia
Interventions
Osteopathic Manipulative Treatment, Sham treatment
Procedure
Lead sponsor
Burrell College of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Cruces, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Not applicable Interventional

Is Osteopathic Manipulative Treatment (OMT) Beneficial for Elderly Patients Hospitalized With Pneumonia?

NCT00258661
View directory record Official record
Conditions
Pneumonia
Interventions
Osteopathic Manipulative Treatment, Light-touch Treatment
Procedure
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
50 Years and older
Enrollment
406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
7
States / cities
Mount Clemens, Michigan • Kirksville, Missouri • Stratford, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2018 · Synced Sep 30, 2026, 1:27 PM EDT
Not listed Not applicable Interventional

Effects of Osteopathic Manipulative Treatment (OMT) on Gait Biomechanics in Parkinson's Disease

NCT03616145
View directory record Official record
Conditions
Parkinson Disease
Interventions
Osteopathic Manipulative Treatment (OMT), Light Touch
Procedure · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Sep 30, 2026, 1:27 PM EDT
Recruiting Phase 1Phase 2 Interventional

Treating Chronic Cervicogenic Head and Neck Pain

NCT05617365
View directory record Official record
Conditions
Cervicogenic Headache, Neck Pain, Posterior
Interventions
Osteopathic Manipulative Therapy and Exercise Therapy
Combination Product
Lead sponsor
Michigan State University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Biomarkers of the Response to Osteopathic Manipulation

NCT00958646
View directory record Official record
Conditions
Healthy
Interventions
Osteopathic Manipulation, Placebo
Other
Lead sponsor
West Virginia School of Osteopathic Medicine
Other
Eligibility
21 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Lewisburg, West Virginia
Source: ClinicalTrials.gov public record
Updated Jul 13, 2011 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Not applicable Interventional

OMT & Intractable Singultus

NCT07149025
View directory record Official record
Conditions
Hiccup
Interventions
Osteopathic Manipulative Therapy
Procedure
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 29, 2025 · Synced Sep 30, 2026, 1:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Osteopathic Manipulation Therapy in the Treatment of Interstitial Cystitis

NCT00873171
View directory record Official record
Conditions
Interstitial Cystitis
Interventions
Not listed
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 30, 2026, 1:27 PM EDT
Completed Phase 2 Interventional

Study of the Effectiveness of Osteopathic Manipulative Treatment in Pregnant Women

NCT00298935
View directory record Official record
Conditions
Low Back Pain, Musculoskeletal Diseases, Pregnancy Complications
Interventions
Osteopathic manipulative treatment (OMT)
Procedure
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years and older · Female only
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 24, 2013 · Synced Sep 30, 2026, 1:27 PM EDT