- Conditions
- Opioid Use, Stimulant Use
- Interventions
- harm reduction intervention
- Behavioral
- Lead sponsor
- Brittany Miller-Roenigk
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 3
- States / cities
- Louisville, Kentucky • Cincinnati, Ohio
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Showing 1–24
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- Conditions
- Human Immunodeficiency Virus
- Interventions
- Intervention Arm (computer-based CARE+ Corrections tool), Educational video on opiate overdose prevention
- Device · Other
- Lead sponsor
- George Washington University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 112 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Accidental Overdose of Opiate
- Interventions
- Overdose prevention resources, Overdose prevention education
- Other · Behavioral
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Accidental Overdose of Opiate
- Interventions
- Take home rapid drug test
- Behavioral
- Lead sponsor
- Brown University
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 93 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Overdose
- Interventions
- Brief youth overdose prevention education, Information about Naloxone, Usual standard of care
- Behavioral · Other
- Lead sponsor
- Boston Medical Center
- Other
- Eligibility
- 13 Years and older
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Substance Use Disorders, Recidivism
- Interventions
- Adolescent Community Reinforcement Approach, Assertive Continuing Care, Trauma Affect Regulation Guide for Education and Therapy, Motivational Interviewing, Opioid Education Workbook
- Behavioral · Other
- Lead sponsor
- Seattle Children's Hospital
- Other
- Eligibility
- 15 Years to 25 Years
- Enrollment
- 215 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Olympia, Washington
- Conditions
- HIV, Hepatitis
- Interventions
- Intervention Condition, Control Condition
- Behavioral
- Lead sponsor
- Johns Hopkins Bloomberg School of Public Health
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 1,024 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003 – 2008
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Overdose
- Interventions
- CSH-Delivered Overdose Prevention Support
- Behavioral
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,350 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- HIV (Human Immunodeficiency Virus), Substance Abuse Disorder
- Interventions
- Community Coalition CLS Workgroup/Network of Providers, Tech-mediated Training and Service Delivery, Multidisciplinary Implementation Team with Champion, Tech-mediated Peer Navigation Enhanced Case management (NCM)
- Behavioral
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 65 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Kingston, New York
- Conditions
- Opioid-use Disorder, Addiction, Depression, Post Traumatic Stress Disorder, Suicidal Ideation
- Interventions
- Collaborative care Plus
- Behavioral
- Lead sponsor
- RAND
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 68 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 12
- States / cities
- Los Angeles, California • Santa Monica, California • Albuquerque, New Mexico + 3 more
- Conditions
- Substance Abuse, Intravenous, Prevention and Control
- Interventions
- Break the Cycle Intervention, Bacterial Infection Prevention
- Behavioral
- Lead sponsor
- New York University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 402 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Opioid Use Disorder, Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe
- Interventions
- TRTME
- Behavioral
- Lead sponsor
- T. John Winhusen, PhD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Sports Medicine Injuries
- Interventions
- LCS (Life Care Specialist), Standard of Care
- Behavioral
- Lead sponsor
- Emory University
- Other
- Eligibility
- 15 Years to 45 Years
- Enrollment
- 148 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 2
- States / cities
- Atlanta, Georgia
- Conditions
- Substance Use (Drugs, Alcohol)
- Interventions
- ED-SMART intervention, Substance use information
- Behavioral
- Lead sponsor
- Purdue University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 650 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Drug Overdose, Opioid-Related Disorders, Drug Addiction, Drug Abuse, Substance Abuse
- Interventions
- Peer Intervention, naloxone nasal spray kit, Personally-tailored opioid overdose prevention education (information packet)
- Behavioral · Drug
- Lead sponsor
- University of Cincinnati
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Opioid Use Disorder
- Interventions
- Buprenorphine
- Drug
- Lead sponsor
- Rhode Island Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Opioid-use Disorder
- Interventions
- PCP brief advice, Video doctor, Telephone health coaching, Nurse Care Manager (NCM) intervention
- Behavioral
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 321 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Opioid-use Disorder
- Interventions
- Patient Navigation, Buprenorphine
- Behavioral · Drug
- Lead sponsor
- Friends Research Institute, Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 373 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland
- Conditions
- Substance Use
- Interventions
- Education and support for primary care providers (PCPS), Nurse Care Manager (NCM) visits, Addiction specialist consultant, Health coaching sessions, Patient educational materials
- Other
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 301 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 8
- States / cities
- Torrance, California • New York, New York • Enterprise, Oregon + 4 more
- Conditions
- Drug Overdose, Opioid Related Disorders
- Interventions
- Therapist-led brief intervention (TBI)
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 139 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Waterford, Michigan
- Conditions
- Opioid Use Disorder, Chronic Pain
- Interventions
- Acceptance and Commitment Therapy + Mindfulness Based Relapse Prevention (ACT + MBRP), Enhance Usual Care (EUC)
- Behavioral
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 2
- States / cities
- Ann Arbor, Michigan • Albuquerque, New Mexico
- Conditions
- Drug Overdose, Opioid-Related Disorders
- Interventions
- TBI - Cohort 1, TBI - Cohort 2
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 204 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Drug Overdose Accidental
- Interventions
- Overdose Prevention Intervention
- Behavioral
- Lead sponsor
- Drexel University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Opioid Use Disorder, Opioid Use Disorder, Severe, Opioid Use Disorder, Moderate
- Interventions
- Standard of Care Referral, Low Threshold Buprenorphine
- Other · Behavioral
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 512 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 8
- States / cities
- Los Angeles, California • Washington D.C., District of Columbia • Baton Rouge, Louisiana + 5 more