Independent directory Public ClinicalTrials.gov records United States
Clear filters
ClinicalTrials.gov public records Last synced Sep 16, 2026, 11:14 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Not applicable Interventional Accepts healthy volunteers

Protective Effect of Exercise on Acute High-fat Overfeeding

NCT07633704
Conditions
Insulin Sensitivity/Resistance
Interventions
High Fat Overfeeding, High Fat Overfeeding + Exercise
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
20 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Not listed Not applicable Interventional Accepts healthy volunteers

Adaptive Responses to Overfeeding and Weight

NCT03857048
Conditions
Obesity
Interventions
Weight Loss, Exercise training, Overfeeding
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 50 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Completed No phase listed Observational

Effects of Diet Changes on Metabolism

NCT00523627
Conditions
Obesity
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 55 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Phoenix, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

Palatability (Energy I Pilot)

NCT01653886
Conditions
Energy Density
Interventions
Breakfast (1-2 hours, in the morning), Lunch (1-2 Hours, at midday), Dinner (1-2 hours, in the afternoon)
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Conditions
Obesity, Diet Therapy, Weight Loss, Weight Gain, Nutrition Therapy
Interventions
Weight Loss, Overfeeding, Overfeeding Low Pro
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 60 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

Fat Cell Size and Overfeeding and Etopic Study

NCT01672632
Conditions
Over Eating
Interventions
Overfeeding
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2020
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Completed Not applicable Interventional Accepts healthy volunteers

White Adipose Tissue Clocks and High Calorie Feeding

NCT02809482
Conditions
Healthy
Interventions
Eucaloric feeding, Overfeeding
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
20 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Denver, Colorado
Conditions
Healthy
Interventions
High calorie diet, Fasting
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 45 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obesity, Thinness, Weight Gain
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
25 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Denver, Colorado
Recruiting Not applicable Interventional Accepts healthy volunteers

Thermogenenic Responses to Fasting and Overfeeding in Women

NCT06610162
Conditions
Obesity
Interventions
Eucalaloric feeding, Acute Fasting, Acute Overfeeding
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Obesity, Normal Physiology, Healthy Volunteers
Interventions
+200% of dietary requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat, fasting, -50% of energy balance requirements. 50% of calories from carbohydrates, 20% from protein, and 30% from fat, +150% of energy balance requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat, +200% of dietary requirements, 51% of the calories from carbohydrates, 46%, from fat and 3% from protein, -25% of energy balance requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat, +150% of dietary requirements, 51% of the calories from carbohydrates, 46%, from fat and 3% from protein
Dietary Supplement
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Energy Imbalance on Food Intake Behaviors

NCT03112161
Conditions
Obesity
Interventions
Eucaloric Feeding Period, Overfeeding Feeding Period, Underfeeding Feeding Period
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
25 Years to 40 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing the Adipose Expandability Hypothesis In Vivo During Overfeeding

NCT04583514
Conditions
Overweight and Obesity, Metabolic Syndrome
Interventions
Control, Overfeeding
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 42 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Completed Phase 3 Interventional Accepts healthy volunteers

Fat Gain and Cardiovascular Disease Mechanisms

NCT00589498
Conditions
Hypertension, Sleep Apnea Syndromes, Obesity
Interventions
1000 extra calories
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 40 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Obesity
Interventions
Vancomycin, Placebo oral tablet, Overfeeding diet (OF), Underfeeding diet (UF)
Drug · Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 45 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Phoenix, Arizona