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ClinicalTrials.gov public records Last synced Oct 9, 2026, 8:24 PM EDT

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Showing 49–64 of 64 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Oxygen via nasal cannula Clear all
Completed Not applicable Interventional

Treating Sleep Apnea Induced Hypoxemia With Oxygen in Acute Stroke Patients

NCT03300063
View directory record Official record
Conditions
Stroke, Acute
Interventions
Low flow nocturnal oxygen
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Oct 9, 2026, 8:24 PM EDT
Completed Early Phase 1 Interventional

Micro-stream Capnography in Non-intubated Lean and Obese Patients With and Without Obstructive Sleep Apnea

NCT00653471
View directory record Official record
Conditions
Obesity, Obstructive Sleep Apnea
Interventions
Microcapmicro-stream device with Smart CapnoLine Plus, Microcap micro-stream device with CapnoLine, TG-920 main-stream device (Nihon Kohden, Tokyo, Japan).
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 20, 2016 · Synced Oct 9, 2026, 8:24 PM EDT
Terminated No phase listed Observational

Treatment of Dyspnea in Do-not-intubate Patients

NCT02114944
View directory record Official record
Conditions
Acute Respiratory Failure, Acute on Chronic Respiratory Failure, Dyspnea
Interventions
NIV, CPAP, Standard oxygen, HFNC
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Oct 9, 2026, 8:24 PM EDT
Completed No phase listed Observational

Prematurity-Related Ventilatory Control

NCT03464396
View directory record Official record
Conditions
Respiratory Control in Premature Infants
Interventions
Bedside Physiology study, Carotid Body Function Test, Room Air Challenge, Hypoxia Challenge Test, Effects of Nasal Cannula Flow, Magnetic Resonance Imaging, Echocardiogram, Blood Sample
Other · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
1 Day to 28 Days
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Oct 9, 2026, 8:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of High Flow Nasal Cannula During Sedation of Morbidly Obese Patients in the Endoscopy Suite

NCT02859597
View directory record Official record
Conditions
Morbid Obesity, Noninvasive Ventilation, Deep Sedation
Interventions
High flow nasal cannula, Nasal Cannula
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 9, 2026, 8:24 PM EDT
Not yet recruiting Not applicable Interventional

ADINA vs. High Flow Nasal Cannula Comparison Study

NCT03171129
View directory record Official record
Conditions
Respiratory Distress Neonatal
Interventions
Adaptive Dynamic Inspiratory Nasal Apparatus, High flow Nasal Canula
Device
Lead sponsor
Loma Linda University
Other
Eligibility
23 Weeks to 40 Weeks
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 9, 2026, 8:24 PM EDT
Completed No phase listed Observational

Investigate the Aerosol Particle Distribution During Aerosol Generating Procedures

NCT04353531
View directory record Official record
Conditions
Transmission, Patient Professional, High-flow Nasal Cannula
Interventions
High-flow nasal cannula, Surgical mask, bronchoscopy examination, intubation, tracheostomy, nebulization, Pulmonary function test
Device · Procedure · Diagnostic Test
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Oct 9, 2026, 8:24 PM EDT
Completed No phase listed Observational

Effective Fraction of Inspired Oxygen With Nasal Cannula in Premature Infants

NCT03431818
View directory record Official record
Conditions
Oxygen Therapy
Interventions
Nasal cannula flow rate
Other
Lead sponsor
University of Miami
Other
Eligibility
Not listed
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 9, 2026, 8:24 PM EDT
Completed Phase 2 Interventional

Two-Part Dose-Confirming Study of Pulsed Inhaled Nitric Oxide in Subjects With WHO Group 3 Pulmonary Hypertension Associated With COPD

NCT01728220
View directory record Official record
Conditions
Pulmonary Hypertension, Chronic Obstructive Pulmonary Disease
Interventions
Inhaled NO delivered via INOpulse DS-C Device, Placebo delivered via INOpulse DS-C Device
Combination Product
Lead sponsor
Bellerophon Pulse Technologies
Industry
Eligibility
40 Years to 80 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
43
States / cities
Jasper, Alabama • Flagstaff, Arizona • Phoenix, Arizona + 35 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2023 · Synced Oct 9, 2026, 8:24 PM EDT
Withdrawn Phase 2 Interventional

iNOPulse for COVID-19

NCT04398290
View directory record Official record
Conditions
COVID-19, Hypoxemia, Hypoxemic Respiratory Failure
Interventions
Inhaled nitric oxide (iNO), Nitrogen gas, Oxygen gas
Drug
Lead sponsor
Roger Alvarez
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Oct 9, 2026, 8:24 PM EDT
Completed Phase 3 Interventional Results available

Long-term Oxygen Treatment Trial

NCT00692198
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Supplemental oxygen therapy
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
40 Years and older
Enrollment
738 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
39
States / cities
Birmingham, Alabama • Duarte, California • Loma Linda, California + 30 more
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 9, 2026, 8:24 PM EDT
Completed Not applicable Interventional

In Line Aerosol Nebulization With High Flow

NCT05880836
View directory record Official record
Conditions
Hypoxemic Respiratory Failure, Airway Obstruction
Interventions
nebulizer via in-line drug delivery maintaining high-flow nasal cannula oxygen, standard jet nebulization (SJN) with face mask
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Los Angeles, California • Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 9, 2026, 8:24 PM EDT
Withdrawn Not applicable Interventional

Employing End Tidal Capnography in Continuous Flow Ventricular Assist Device Patients

NCT02838355
View directory record Official record
Conditions
Cardiomyopathy, Cardiovascular Disease, Heart Disease
Interventions
Respiratory Depression Monitoring with End Tidal Carbon Dioxide Nasal Cannula (ETCO2- NC), Standard Non-invasive Respiratory Depression Monitoring
Device · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced Oct 9, 2026, 8:24 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

TD-0903 Pharmacokinetics Study in Healthy Participants With Supplemental Oxygenation

NCT05091723
View directory record Official record
Conditions
Acute Lung Injury (ALI) Due to Coronavirus Disease-2019 (COVID-19)
Interventions
Nezulcitinib (TD-0903) Dose A, Nezulcitinib (TD-0903) Dose B
Drug
Lead sponsor
Theravance Biopharma
Industry
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Cypress, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2021 · Synced Oct 9, 2026, 8:24 PM EDT
Completed Not applicable Interventional Results available

Comparison of Oxygenation and Ventilation With a Novel Nasal Mask Versus Standard of Care During Colonoscopy

NCT03139448
View directory record Official record
Conditions
Colonoscopy, Oxygenation, Ventilation
Interventions
Oxygen via nasal cannula, Oxygen via SuperNO2VA nasal mask
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Oct 9, 2026, 8:24 PM EDT
Completed Phase 2 Interventional

Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea

NCT03189173
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Oral appliance, Oxygen, Oral appliance plus oxygen, No treatment
Device · Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 79 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 9, 2026, 8:24 PM EDT