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Conditions: Type 2 Diabetes, Pre-Diabetes
Interventions: Men-Tailored DPP (Power-Up); Other
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 18 Years and older · Male only
Enrollment: 301 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Congestive Heart Failure
Interventions: blood volume measurement, venous plethysmography; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Diabetes Mellitus, Hypertension, Hyperlipidemia
Interventions: Monthly Financial Incentive, Final Financial Incentive; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: ANCA Associated Vasculitis
Interventions: ENUMERATION OF CD5+ B Cells; Device
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 85 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Oxygen Saturation
Interventions: Clarifi Modulum, Perimed PeriFlux 5000, Apple Watch Oxygen Sensor, Innovo iP 900AP; Device
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 2
States / cities: Indianapolis, Indiana • Pittsburgh, Pennsylvania

Conditions: Oropharyngeal Squamous Cell Carcinoma
Interventions: Transoral Robotic Surgery (TORS) or Radiotherapy, Chemotherapy and Low-Dose Radiotherapy, Chemotherapy and High-Dose Radiotherapy, Paclitaxel, Carboplatin; Other · Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Iron Deficiency Anemia, Iron Overload
Interventions: Ferrous sulfate, Aspiron, Placebo; Dietary Supplement · Other
Lead sponsor: Iowa State University; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Ames, Iowa

Conditions: Acute Lung Injury, Acute Respiratory Distress Syndrome, Mechanical Ventilation
Interventions: APRV, Conventional MV; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Gestational Diabetes Mellitus in Pregnancy, Type 2 Diabetes
Interventions: OneTouch Reveal application; Behavioral
Lead sponsor: Carolyn Zahler-Miller; Other
Eligibility: 18 Years to 100 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Sepsis
Interventions: Biomarker Algorithm Intervention; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: Not listed
Enrollment: 145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Neuromuscular Blockade, Muscle Relaxation
Interventions: Train of four test; Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 85 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: New York, New York

Conditions: Hemophilia A
Interventions: rFVIII-FS/pegylated liposomes (BAY79-4980), rFVIII-FS/WFI (BAY14-2222); Biological
Lead sponsor: Bayer; Industry
Eligibility: 12 Years to 70 Years · Male only
Enrollment: 143 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 20
States / cities: Orange, California • Sacramento, California • San Francisco, California + 17 more

Conditions: PreDiabetes
Interventions: Group Lifestyle Balance (GLB), Group Lifestyle Balance Plus (GLB+); Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 21 Years and older
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Community-Acquired Pneumonia, Antimicrobial Stewardship, Point-of-Care Testing
Interventions: Rapid Diagnostic Testing, Pharmacist-led de-escalation; Diagnostic Test · Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 28,580 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 12
States / cities: Vero Beach, Florida • Weston, Florida • Akron, Ohio + 8 more

Conditions: Rabies, Rabies Immunisation
Interventions: ChAd155-RG, Placebo, Rabies Vaccine; Biological · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 49 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Decatur, Georgia

Conditions: Gastroparesis
Interventions: ML1101 Stimulus Isolator, Vagal Maneuver; Device · Procedure
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 131 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2030
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Multiple Myeloma
Interventions: Belantamab mafodotin frozen liquid, Belantamab mafodotin lyophilized powder; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years and older
Enrollment: 221 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 21
States / cities: New Haven, Connecticut • Atlanta, Georgia • Chicago, Illinois + 15 more

Conditions: Opioid Use Disorder, Sleep Disturbance
Interventions: Post-Illumination Pupillary Response (PIPR), Polysomnography, Multiple Sleep Latency Test, Ecological Momentary Assessments, Actigraphy, DLMO, Melatonin Suppression Test; Other · Behavioral · Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 80 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Tobacco Use Treatment
Interventions: Audit and performance feedback (PF), Financial Incentive (P4P), Current Best Practices (CBP); Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 3,207 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 2
States / cities: New York, New York

Conditions: Multiple Myeloma
Interventions: Epoetin Alfa, Exercise, Autologous Peripheral Blood Stem Cell Transplantation, Red Blood Cell Transfusion, Thalidomide, Heparin, Low-Molecular-Weight, Platelet Transfusion, Melphalan, Total Therapy II; Drug · Behavioral · Biological
Lead sponsor: University of Arkansas; Other
Eligibility: Not listed
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2004
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Kidney Injury, Pre-Term
Interventions: Caffeine citrate, Placebo; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 12 Hours to 96 Hours
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: LRTI
Interventions: PCT Arm; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 189 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Bone Sarcoma, Osteosarcoma, Chondrosarcoma, Ewing's Sarcoma, Osseous Sarcoma, Bone Neoplasm
Interventions: Toronto Extremity Salvage Score, Musculoskeletal Tumor Society Score, Timed Get Up and Go Test, Orthogonal Radiographs, Weight Bearing for lower extremities only, Range of Motion; Behavioral · Diagnostic Test
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 4 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 5
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Harrison, New York + 2 more

Conditions: Diabetes, Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Interventions: Diabetes Self-Management Training (DSMT), Remote Glucose Monitoring (RGM), Community Health Worker tailored support; Behavioral
Lead sponsor: Sinai Health System; Other
Eligibility: 18 Years and older
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

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Power-Up: An Effectiveness Trial of the Diabetes Prevention Program

Blood Volume and Hemodynamic Analysis in Patients With Chronic Heart Failure

Financial Incentives for Medication Adherence

Tailoring Maintenance Therapy to Cluster of Differentiation 5 Positive (CD5+) Regulatory B Cell Recovery in ANCA Vasculitis

Comparison of Tissue Oxygenation Measurement Using Multimodal Devices

Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal Cancer

Iron Supplementation and Side Effects

Airway Pressure Release Ventilation in Acute Lung Injury

Mobile App Logging for Diabetes in Pregnancy

Using Biomarkers to Optimize Antibiotic Strategies in Sepsis

Clinical Application of "Train of Four" Testing in the Intraoperative Monitoring Setting

BAY79-4980 Compared to rFVIII-FS in Previously Treated Patients With Severe Hemophilia A

Augmented Care at Worksite for Diabetes Prevention

Reducing Antimicrobial Overuse Through Targeted Therapy for Patients With Community-Acquired Pneumonia

Dosage-Escalation Study of the Safety and Immunogenicity of a Novel Rabies Vaccine ChAd155-RG vs. the Comparator RABAVERT Vaccine in Healthy Adult Subjects

ABVN Phase 2-Studying the Effect of Stimulation on the Auricular Branch of the Vagal Nerve

A Study to Investigate the Efficacy and Safety of Two Doses of GSK2857916 in Participants With Multiple Myeloma Who Have Failed Prior Treatment With an Anti-CD38 Antibody

Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment

Dentistry United to Extinguish Tobacco

Effects of Exercise in Combination With Epoetin Alfa

Improving Preterm Kidney Outcomes With Caffeine

Procalcitonin for Stewardship in Respiratory Infections A Stewardship Project

Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

Improving Diabetes Equity and Advancing Care Study