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Showing 1–24 of 82 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: PD exercise Clear all
Recruiting Not applicable Interventional

Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease

NCT06088355
View directory record Official record
Conditions
Parkinson Disease, Movement Disorders, Neurodegeneration
Interventions
HV-PDAE: High Volume Partnered Dance Aerobic Exercise, MV-PDAE: Moderate Volume Partnered Dance Aerobic Exercise, MV-WALK: Moderate Volume Walking, HV-WALK: High Volume Walking
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional

In-home Cycling for Individuals With PD: Effectiveness

NCT06616948
View directory record Official record
Conditions
Parkinson Disease
Interventions
Social Cycling Group, coaching calls, No coaching calls
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
45 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional

Telephone-Based Counseling for Depression in Parkinson's Disease

NCT02505737
View directory record Official record
Conditions
Depression, Parkinson's Disease
Interventions
TH-CBT, Enhanced Usual Care
Behavioral · Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
35 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Sep 5, 2026, 5:24 AM EDT
Not listed Not applicable Interventional

Exercise Targeting Cognitive Impairment in Parkinson's Disease

NCT02267785
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Skill-Based Exercise, Aerobic Exercise, Social Contact
Other
Lead sponsor
University of Southern California
Other
Eligibility
30 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Phase 2 Interventional

Phase 2b Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Parallel-Group Study to Assess the PD Response and Safety of Three Dose Levels of (PB1023) Injection Following 20 Weeks of Weekly SC Dosing in Adults With T2DM

NCT01658501
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
50 mg PB1023, 70 mg PB1023, 100 mg PB1023, Placebo (0.9% Sodium Chloride), Victoza®, Diet and Exercise, Metformin, Sulfonylurea, Metformin and Sulfonylurea
Drug · Other
Lead sponsor
PhaseBio Pharmaceuticals Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
593 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
93
States / cities
Anniston, Alabama • Birmingham, Alabama • Gulf Shores, Alabama + 90 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2015 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Motor Training in PD

NCT02457832
View directory record Official record
Conditions
Parkinson Disease
Interventions
Adapted Tango Dancing, Behavioral Control (BC) Condition
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 70 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional

Endurance Exercise & Virtual Reality for Optimizing Cortical Excitability and Neuroplasticity in PD

NCT06133283
View directory record Official record
Conditions
Parkinson Disease
Interventions
High intensity endurance exercise, Stretching exercise, Virtual reality (VR)-based gaming
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional Results available

Immersive Virtual Reality Bicycling for Persons With Parkinson's Disease

NCT05160025
View directory record Official record
Conditions
Parkinson Disease
Interventions
Virtual reality bicycling
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
45 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise, Brain Imaging, Cognition, and Gait in Parkinsonism

NCT02231073
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Exercise and Education for Parkinson's Disease
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
50 Years to 90 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Phase 2 Interventional Results available

Masked Faces in Parkinson Disease: Mechanism and Treatment

NCT00350402
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Respiratory muscle strength training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
45 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 5, 2012 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional Results available

Kick Out Parkinson's Disease- Karate Intervention

NCT03555695
View directory record Official record
Conditions
Parkinson Disease
Interventions
Karate Classes, Pre-Intervention Focus Group, Post-Intervention Focus Group
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
30 Years to 90 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional Results available

FitMi PD Home Therapy for Parkinson's Disease

NCT05655377
View directory record Official record
Conditions
Parkinson Disease
Interventions
FitMi PD
Device
Lead sponsor
Flint Rehabilitation Devices, LLC
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Sep 5, 2026, 5:24 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

iPACES v3 MCI NIA Protocol Copied for iPACES v4 PD NINDS

NCT05810454
View directory record Official record
Conditions
Parkinson's Disease, PD, Mild Cognitive Impairment, MCI
Interventions
iPACES (interactive Physical and Cognitive Exercise System), PACE (Physical and Cognitive Exercise)
Device
Lead sponsor
iPACES LLC
Industry
Eligibility
50 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Clifton Park, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parkinson's Autonomic Responses to Treadmill Walking

NCT03156400
View directory record Official record
Conditions
Parkinson Disease, Autonomic Dysfunction
Interventions
Exercise Stress Test
Other
Lead sponsor
University of Miami
Other
Eligibility
50 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Sep 5, 2026, 5:24 AM EDT
Not listed Not applicable Interventional

Slow Wave Sleep As a Biomarker of Rehabilitation-induced Cognitive Improvement in PD

NCT04796506
View directory record Official record
Conditions
Parkinson Disease
Interventions
Progressive Resistance Training (PRT), Delayed Exercise Training (DE), Endurance Training (ET)
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
45 Years to 100 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Sep 5, 2026, 5:24 AM EDT
Suspended Not applicable Interventional

The Effect of Diet and Exercise on ImmuNotherapy and the Microbiome (EDEN)

NCT04866810
View directory record Official record
Conditions
Melanoma
Interventions
Intervention Arm, Control
Behavioral
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 120 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Loma Linda, California • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional

The Effects of Treadmill Versus Agility Training in Parkinson's Disease

NCT00982709
View directory record Official record
Conditions
Exercise, Parkinson's Disease
Interventions
Aerobic vs. Agility Training
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
50 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 2, 2014 · Synced Sep 5, 2026, 5:24 AM EDT
Recruiting Not applicable Interventional

Accelerated TMS for Freezing of Gait in Parkinson's Disease

NCT06982638
View directory record Official record
Conditions
Parkinson's Disease (PD)
Interventions
TMS+ Gait training
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
50 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional

Pre-Active PD: Looking At Physical Activity Behavior Change in Parkinson's Disease

NCT05308238
View directory record Official record
Conditions
Parkinson Disease
Interventions
Occupational therapy intervention group, Disease management education group
Behavioral
Lead sponsor
San Jose State University
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
San Jose, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional Results available

Kick Out Parkinson's Disease 2

NCT03882879
View directory record Official record
Conditions
Parkinson Disease
Interventions
Karate Classes, Pre-Intervention Study Visit, Bimonthly Online Survey, 6-month Study Visit, 12-month Study Visit
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
30 Years to 90 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional Results available

Randomized Trial to Test the "Coordinated Care for Health Promotion and Activities in Parkinson's Disease" Intervention in the VA

NCT01532986
View directory record Official record
Conditions
Parkinson Disease
Interventions
Coordinated care management for Parkinson's disease, Educational handout
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
345 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
5
States / cities
Loma Linda, California • Long Beach, California • San Diego, California + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 7, 2019 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Not applicable Interventional Results available

Community Exercise for Fall Risk in PD

NCT05940077
View directory record Official record
Conditions
Parkinson Disease, Fall, Exercise
Interventions
Exercise
Behavioral
Lead sponsor
Idaho State University
Other
Eligibility
30 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pocatello, Idaho
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 5, 2026, 5:24 AM EDT
Completed Phase 2 Interventional

High-intensity Exercise and Fall Prevention Boot Camp for Parkinson's Disease

NCT02230267
View directory record Official record
Conditions
Parkinson's Disease
Interventions
High intensity exercise and balance training, Usual care arm exercise
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
45 Years to 85 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Sep 5, 2026, 5:24 AM EDT
Recruiting No phase listed Observational

Adaptive DBS to Offset STN Dysregulation During Exercise in PD

NCT06296810
View directory record Official record
Conditions
Parkinson Disease
Interventions
aDBS
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
20 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Sep 5, 2026, 5:24 AM EDT