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ClinicalTrials.gov public records Last synced Nov 13, 2026, 10:14 AM EST

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Showing 25–48 of 80 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: PEG3350 Clear all
Completed No phase listed Observational Accepts healthy volunteers Results available

Residual Gastric Volume in Same Day Versus Split Dose and Evening Before Bowel Preparation

NCT02264249
View directory record Official record
Conditions
Esophagogastroduodenoscopy, Colonoscopy
Interventions
Esophagogastroduodenoscopy and colonoscopy split dose prep, Esophagogastroduodenoscopy and colonoscopy Evening before colonoscopy prep, Esophagogastroduodenoscopy and colonoscopy Same day prep colonoscopy preparation
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
449 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Nov 13, 2026, 10:14 AM EST
Recruiting Phase 4 Interventional Accepts healthy volunteers

Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen

NCT05821309
View directory record Official record
Conditions
Constipation
Interventions
PEG 3350, PEG-3350 with electrolytes, Glycerin
Drug
Lead sponsor
Indiana University
Other
Eligibility
2 Years to 18 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Nov 13, 2026, 10:14 AM EST
Completed Phase 4 Interventional

Preference of Tegaserod vs. PEG 3350 in Patients With Constipation

NCT00171522
View directory record Official record
Conditions
Constipation
Interventions
Tegaserod and Polyethylene Glycol 3350
Drug
Lead sponsor
Novartis
Industry
Eligibility
18 Years to 64 Years · Female only
Enrollment
52 participants
Timeline
2005
U.S. locations
14
States / cities
Oro Valley, Arizona • Phoenix, Arizona • Tucson, Arizona + 11 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Nov 13, 2026, 10:14 AM EST
Terminated Phase 4 Interventional Results available

Bowel Preparation for Colonoscopy in Children

NCT01140295
View directory record Official record
Conditions
Colonoscopy Preparation
Interventions
polyethylene glycol, senna
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Years to 21 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2013 · Synced Nov 13, 2026, 10:14 AM EST
Withdrawn Phase 3 Interventional

The Effect of Naloxegol on Refractory Constipation in the Intensive Care Unit

NCT02705378
View directory record Official record
Conditions
Constipation, Critical Illness
Interventions
Polyethylene glycol, naloxegol
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 5, 2021 · Synced Nov 13, 2026, 10:14 AM EST
Completed Phase 2 Interventional Results available

Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease

NCT02765256
View directory record Official record
Conditions
Crohn's Disease
Interventions
Fluconazole, Vancomycin, Neomycin, Ciprofloxacin, Polyethylene Glycol 3350, Promethazine, Fluconazole placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Nov 13, 2026, 10:14 AM EST
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Miralax (PEG 3350) vs. Golytely as Bowel Preparation for Screening Colonoscopy

NCT01170754
View directory record Official record
Conditions
Colon Cancer
Interventions
PEG-3350 and Gatorade, Golytely 4 liters
Drug
Lead sponsor
Temple University
Other
Eligibility
40 Years to 75 Years
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Nov 13, 2026, 10:14 AM EST
Completed Not applicable Interventional

MiraLAX Versus Placebo to Prevent Constipation Following Urogynecologic Surgery

NCT01691742
View directory record Official record
Conditions
Post Procedural Constipation
Interventions
MiraLax, Placebo, Rescue Laxative
Drug
Lead sponsor
Duke University
Other
Eligibility
19 Years and older · Female only
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 15, 2017 · Synced Nov 13, 2026, 10:14 AM EST
Terminated Not applicable Interventional Results available

Efficacy of Lubiprostone in Combination With Standard PEG Preparation

NCT00689026
View directory record Official record
Conditions
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Interventions
Lubiprostone, Polyethylene glycol with electrolytes
Drug · Other
Lead sponsor
Augusta University
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 20, 2014 · Synced Nov 13, 2026, 10:14 AM EST
Completed Phase 4 Interventional

Assessment of Safety, Quality, and Acceptance of a Bowel Preparation Using a Food Kit With Laxatives

NCT07605897
View directory record Official record
Conditions
Bowel Preparation, Efficacy, Tolerability, Safety, Colon Cancer Screening, Bowel Preparation for Colonoscopy
Interventions
Use of a standardized meal content (food-kit) the day prior to colonoscopy, Polyethylene glycol 3350 - electrolyte solution (GoLYTELY)
Other · Drug
Lead sponsor
Joseph Spataro
Federal
Eligibility
18 Years to 69 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Nov 13, 2026, 10:14 AM EST
Completed Phase 4 Interventional Results available

Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic Surgery

NCT06159777
View directory record Official record
Conditions
Constipation, Surgical Procedure, Unspecified, Prolapse; Female
Interventions
Polyethylene Glycol 3350
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Nov 13, 2026, 10:14 AM EST
Completed Phase 3 Interventional Results available

BLI850 vs an Active Control Bowel Preparation in Adult Subjects Undergoing Colonoscopy

NCT00756977
View directory record Official record
Conditions
Colon Cancer
Interventions
BLI850, polyethylene glycol 3350 based bowel preparation
Drug
Lead sponsor
Braintree Laboratories
Industry
Eligibility
18 Years and older
Enrollment
394 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
12
States / cities
Mobile, Alabama • Jupiter, Florida • Miami, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 15, 2013 · Synced Nov 13, 2026, 10:14 AM EST
Completed Phase 2 Interventional Results available

Macrogol 3350-based Oral Osmotic Laxative in Preventing Cancer in Patients at Risk of Colorectal Cancer

NCT00828984
View directory record Official record
Conditions
Adenomatous Polyp, Colorectal Carcinoma
Interventions
macrogol 3350-based oral osmotic laxative, Placebo, Laboratory Biomarker Analysis
Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
3
States / cities
Chicago, Illinois • Evanston, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Nov 13, 2026, 10:14 AM EST
Completed Phase 4 Interventional Accepts healthy volunteers

Reduction of Postoperative Gastrointestinal Dysmotility Following Total Laparoscopic Hysterectomy.

NCT03800745
View directory record Official record
Conditions
Postoperative Passage of Flatus, Postoperative Bowel Movement
Interventions
Colace 100Mg Capsule, Miralax
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Nov 13, 2026, 10:14 AM EST
Completed Phase 4 Interventional

A Safety and Efficacy Evaluation of 3 Bowel Preparations in the Pediatric Population

NCT00425594
View directory record Official record
Conditions
Colonoscopy
Interventions
HalfLytely and Bisacodyl Tablets - Formulation 1, HalfLytely and Bisacodyl Tablets - Formulation 2, NuLYTELY
Drug
Lead sponsor
Braintree Laboratories
Industry
Eligibility
6 Years to 16 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
26
States / cities
Birmingham, Alabama • Mobile, Alabama • Tuscaloosa, Alabama + 23 more
Source: ClinicalTrials.gov public record
Updated Dec 27, 2007 · Synced Nov 13, 2026, 10:14 AM EST
Terminated Phase 4 Interventional Results available

Comparison of Clenpiq vs Golytely Bowel Preparation

NCT03198221
View directory record Official record
Conditions
Bowel Preparation Solutions
Interventions
Golytely, Clenpiq
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Nov 13, 2026, 10:14 AM EST
Not listed Phase 4 Interventional

Clostridial Infection and Oral Lavage -Improving Treatment Before Illness Becomes Severe

NCT01630096
View directory record Official record
Conditions
Clostridium Difficile Colitis
Interventions
Nu-Lytely
Drug
Lead sponsor
Ascension Health
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Grand Blanc, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 17, 2012 · Synced Nov 13, 2026, 10:14 AM EST
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Trial Comparing Split-Dose Miralax With Amitiza Pretreatment Versus Dulcolax Pretreatment Versus Golytely for Bowel Cleansing Prior to Colonoscopy

NCT00953017
View directory record Official record
Conditions
Colonoscopy
Interventions
Miralax (PEG 3350), Amitiza (Lubiprostone), Dulcolax (Bisacodyl), Golytely (polyethylene glycol)
Drug
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
425 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 30, 2012 · Synced Nov 13, 2026, 10:14 AM EST
Terminated Phase 1Phase 2 Interventional

Fecal Microbial Transplant in Pediatric Crohn's Disease

NCT02272868
View directory record Official record
Conditions
Crohn's Disease
Interventions
Fecal Microbial transplant, Normal Saline, rifaximin+omeprazole+miralax
Biological · Drug
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Nov 13, 2026, 10:14 AM EST
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Gatorade/Miralax With or Without Bisacodyl Versus NuLytely for Colonoscopy Preparation

NCT01063049
View directory record Official record
Conditions
Preparation for Colonoscopy
Interventions
Gatorade/Miralax, NuLytely, Bisacodyl, Placebo
Drug
Lead sponsor
Gastroenterology Services, Ltd.
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Downers Grove, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 18, 2013 · Synced Nov 13, 2026, 10:14 AM EST
Completed Phase 4 Interventional Results available

Study to Gather Information on the Acceptability of a New Flavor System With Increasing Levels of 2, 4, 6 g or Higher of Mannitol for PEG 3350 in Subjects Having Infrequent Bowel Movements.

NCT04534465
View directory record Official record
Conditions
Constipation
Interventions
Polyethylene glycol (MiraLAX, BAY81-8430), Mannitol
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Nov 13, 2026, 10:14 AM EST
Recruiting Phase 4 Interventional Accepts healthy volunteers

PEG3350 vs Senna After Urogyn Surgery

NCT06825260
View directory record Official record
Conditions
Obstructive Defecation Syndrome, Postoperative Constipation
Interventions
Senna, Polyethylene glycol 3350
Drug
Lead sponsor
St. Joseph's Health, New York
Other
Eligibility
18 Years and older · Female only
Enrollment
254 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Nov 13, 2026, 10:14 AM EST
Recruiting Not applicable Interventional

Low FODMAP Plus PEG 3350 for the Treatment of Patients with Irritable Bowel Syndrome-Constipation

NCT03687814
View directory record Official record
Conditions
Irritable Bowel Syndrome Characterized by Constipation
Interventions
Low FODMAP diet/PEG 3350, sham diet/PEG 3350
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Nov 13, 2026, 10:14 AM EST
Recruiting Phase 4 Interventional Accepts healthy volunteers

Preop Laxatives in Robotic Urologic Surgery

NCT05805436
View directory record Official record
Conditions
Prostate Cancer, Kidney Cancer, Constipation
Interventions
Polyethylene Glycol 3350
Drug
Lead sponsor
Chad R. Tracy
Other
Eligibility
30 Years to 100 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Nov 13, 2026, 10:14 AM EST