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Showing 1–18 of 18 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: PERSONA Total Knee Clear all
Not yet recruiting Not applicable Interventional

Using a Smart Implantable Device to Compare Early Recovery in Two Different Knee Arthroplasty Approaches

NCT07348835
View directory record Official record
Conditions
Total Knee Anthroplasty
Interventions
Total Knee Arthroplasty Medial Parapatellar Approach, Total Knee Arthroplasty Subvastus Approach
Procedure
Lead sponsor
Total Joint Specialists
Network
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sandy Springs, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 7, 2026, 10:19 AM EDT
Completed No phase listed Observational Results available

Analysis of Competitive Posterior Cruciate Retaining (PCR) and Posterior Stabilized (PS) Total Knee Arthroplasty (TKA)

NCT04321356
View directory record Official record
Conditions
Knee Osteoarthritis, Total Knee Arthroplasty, Knee
Interventions
Triathlon PCR TKA, Triathlon PS TKA, Persona PCR TKA, Persona PS TKA
Device
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 7, 2026, 10:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study of the Construct Validity of Community Walking Speed Data Collected Remotely With the Canary canturioTM te Tibial Extension

NCT05539326
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Performance Clinical Outcome Test
Other
Lead sponsor
Canary Medical
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
6
States / cities
Frisco, Colorado • South Bend, Indiana • Jackson, Mississippi + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Sep 7, 2026, 10:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

ROSA Robot Used in Total Knee Replacement Post Market Study

NCT03969654
View directory record Official record
Conditions
Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities, Rheumatoid Arthritis
Interventions
PERSONA Total Knee, Vanguard Total Knee, NexGen Total Knee
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
5
States / cities
Vail, Colorado • Westminster, Colorado • Springfield, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Sep 7, 2026, 10:19 AM EDT
Recruiting No phase listed Observational

A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension

NCT06040827
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Total Knee Arthroplasty
Device
Lead sponsor
Canary Medical
Industry
Eligibility
18 Years and older
Enrollment
626 participants
Timeline
2023 – 2028
U.S. locations
7
States / cities
Fayetteville, Arkansas • Tampa, Florida • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Sep 7, 2026, 10:19 AM EDT
Completed Not applicable Interventional Results available

Persona TM Tibia Clinical Outcomes Study

NCT03589300
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Collagen Disorders and/or Avascular Necrosis of the Femoral Condyle, Post-traumatic Loss of Joint Configuration, Moderate Valgus, Varus, or Flexion Deformities
Interventions
Persona TM Tibia
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
7
States / cities
Torrance, California • Wheat Ridge, Colorado • Honolulu, Hawaii + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Sep 7, 2026, 10:19 AM EDT
Completed No phase listed Observational Results available

Knee Kinematics for Subjects With Zimmer-Biomet Posterior Cruciate Retaining or Posterior Stabilizing Total Knee Arthroplasty

NCT04103515
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee, Osteoarthritis, Knee
Interventions
Zimmer-Biomet Posterior Cruciate Retaining total knee arthroplasty, Zimmer-Biomet Posterior Stabilizing total knee arthroplasty
Device
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Bryn Mawr, Pennsylvania • Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Sep 7, 2026, 10:19 AM EDT
Active, not recruiting Not applicable Interventional

Cemented vs Cementless Persona Keel RCT

NCT05630053
View directory record Official record
Conditions
Knee Pain Chronic, Rheumatoid Arthritis, Osteoarthritis, Traumatic Arthritis, Polyarthritis, Avascular Necrosis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee
Interventions
Cementless Persona Knee System, Cemented Persona Knee System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
7
States / cities
Westminster, Colorado • Chicago, Illinois • Baltimore, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Sep 7, 2026, 10:19 AM EDT
Active, not recruiting Not applicable Interventional

Persona Ti-Nidium Post-Market Clinical Follow-up

NCT04817969
View directory record Official record
Conditions
Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of the Knee, Avascular Necrosis, Patellofemoral Osteoarthritis
Interventions
Zimmer Biomet Persona Ti-Nidium Total Knee System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2034
U.S. locations
7
States / cities
Parker, Colorado • Hyattsville, Maryland • Jackson, Mississippi + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 7, 2026, 10:19 AM EDT
Enrolling by invitation No phase listed Observational

Persona SoluTion PPS Femur PMCF

NCT07286513
View directory record Official record
Conditions
Rhematoid Arthritis, Osteo Arthritis of the Knee, Traumatic Arthritis of Knee (Diagnosis), Polyarthritis, Collagen Disorders, Avascular Necrosis of Femoral Condyle, Valgus Deformity, Varus Deformity, Flexion Deformity of Knee
Interventions
Total knee arthroplasty
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2037
U.S. locations
3
States / cities
Denver, Colorado • Louisville, Kentucky • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 7, 2026, 10:19 AM EDT
Recruiting Not applicable Interventional

Persona MC vs PS RCT With ROSA

NCT05391828
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Zimmer-Biomet Persona Medial Congruent (MC) Bearing Design, Zimmer-Biomet Persona Posterior-Stabilized (PS) Bearing Design
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 7, 2026, 10:19 AM EDT
Recruiting No phase listed Observational

Persona Revision Knee System Outcomes

NCT04821154
View directory record Official record
Conditions
Arthroplasty Complications, Infection, Knee Disease, Knee Osteoarthritis
Interventions
Persona Revision Knee System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2033
U.S. locations
16
States / cities
Fayetteville, Arkansas • Little Rock, Arkansas • Fresno, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 7, 2026, 10:19 AM EDT
Not listed No phase listed Observational

Intraoperative Soft Tissue Balance in TKA

NCT05006274
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Persona Trabecular Metal Tibia, Verasense technology, MUVR
Device
Lead sponsor
Washington Hospital Healthcare System
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Fremont, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2021 · Synced Sep 7, 2026, 10:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating Patient Satisfaction With Smart Knee Implants

NCT06968143
View directory record Official record
Conditions
Total Knee Arthroplasty, Knee Replacement, Knee Replacement Arthroplasty, Knee Osteoarthritis
Interventions
Smart Knee Implant
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 7, 2026, 10:19 AM EDT
Active, not recruiting Not applicable Interventional

Persona Total Knee Arthroplasty Outcomes Study

NCT02255383
View directory record Official record
Conditions
Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Moderate Varus, Valgus or Flexion Deformities, Avascular Necrosis of the Femoral Condyle
Interventions
Zimmer Persona Total Knee System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 75 Years
Enrollment
737 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
14
States / cities
Denver, Colorado • Fort Collins, Colorado • Parker, Colorado + 11 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 7, 2026, 10:19 AM EDT
Active, not recruiting No phase listed Observational

Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)

NCT05787821
View directory record Official record
Conditions
Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
Interventions
Total Knee Arthroplasty
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
760 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2035
U.S. locations
16
States / cities
Parker, Colorado • Tampa, Florida • Atlanta, Georgia + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 7, 2026, 10:19 AM EDT
Active, not recruiting No phase listed Observational

Persona IQ Cohort Study

NCT06089291
View directory record Official record
Conditions
Osteo Arthritis Knee, Knee Arthritis, Monitoring Orthopedic Devices, Total Knee Arthroplasty, Total Knee Replacement
Interventions
Persona IQ
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Granger, Indiana • St Louis, Missouri • Charlotte, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 7, 2026, 10:19 AM EDT
Completed Not applicable Interventional Results available

Zimmer POLAR - Total Knee Arthroplasty (TKA)

NCT01859130
View directory record Official record
Conditions
Osteoarthritis, RheumatoId Arthritis, Traumatic Arthritis, Polyarthritis
Interventions
Zimmer Persona Total Knee System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 75 Years
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
4
States / cities
Naperville, Illinois • Egg Harbor, New Jersey • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Sep 7, 2026, 10:19 AM EDT