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ClinicalTrials.gov public records Last synced Oct 23, 2026, 8:09 AM EDT

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Showing 625–648 of 1,438 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Results available

Continuous Diffusion of Oxygen (CDO) Treatment for Healing of Diabetic Foot Ulcers

NCT02501538
View directory record Official record
Conditions
Foot Ulcer, Diabetic
Interventions
Transcutaneous O2 device
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Oct 23, 2026, 8:09 AM EDT
Completed Not applicable Interventional Results available

Cryotherapy for the Prevention of Taxane-Induced Sensory Neuropathy of the Hands and Feet in Breast Cancer Patients

NCT04256512
View directory record Official record
Conditions
Breast Carcinoma
Interventions
Medical Device Usage and Evaluation, Questionnaire Administration
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Oct 23, 2026, 8:09 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Intrinsic Foot Muscle Strengthening Interventions for Older Adults

NCT05829369
View directory record Official record
Conditions
Accidental Fall
Interventions
Intrinsic foot muscle strengthening exercises, Minimal footwear with prescribed walking, Control
Other
Lead sponsor
Springfield College
Other
Eligibility
65 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Oct 23, 2026, 8:09 AM EDT
Recruiting Phase 2 Interventional

Assessment of Medrol Dosepak to Reduce Opioid Consumption in Foot and Ankle Surgical Patients

NCT06780202
View directory record Official record
Conditions
Foot Injuries and Disorders, Ankle Injuries and Disorders, Achilles Tendon Injury
Interventions
medrol dosepak, HYDROcodone Oral Tablet
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 95 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia • Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 23, 2026, 8:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Early Weight Bearing Tarsometatarsal Fusion Study

NCT03812237
View directory record Official record
Conditions
Hallux Valgus
Interventions
(EWB) Early Weight Bearing (2 Weeks Post-op)
Other
Lead sponsor
Orthopaedic Associates of Michigan, PC
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Oct 23, 2026, 8:09 AM EDT
Completed Not applicable Interventional

A Study Examining Changes in Pain After Manual Therapy in People With Achilles Tendon Pain

NCT06134856
View directory record Official record
Conditions
Achilles Tendinopathy, Ankle Strain, Achilles Tendon Pain, Achilles Tendonitis
Interventions
Ankle mobilization, Sham treatment
Procedure
Lead sponsor
Philadelphia College of Osteopathic Medicine
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Suwanee, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 23, 2026, 8:09 AM EDT
Completed Not applicable Interventional

Functional and Structural Imaging and Motor Control in Spinocerebellar Ataxia

NCT02488031
View directory record Official record
Conditions
Spinocerebellar Ataxia
Interventions
Error-reduction, International Cooperative Ataxia Rating Scale, Scale for the Assessment and Rating of Ataxia, Beck Depression Inventory, 2nd Ed, Stroop, Purdue Pegboard, Brief Test of Attention, 6-minute Walk, Hand Grip Dynamometer, Montreal Cognitive Assessment, Physical Performance Function, Biomechanical Assessments of Dysmetria, Neurophysiological assessment of brain activity, Biomechanical gait analysis
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 85 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 13, 2019 · Synced Oct 23, 2026, 8:09 AM EDT
Terminated Phase 4 Interventional Results available

Use of INTEGRA™ Flowable Wound Matrix to Manage Diabetic Foot Ulcers

NCT01108263
View directory record Official record
Conditions
Diabetes, Foot Ulcer
Interventions
INTEGRA™ Flowable Matrix (Collagen)
Drug
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 17, 2014 · Synced Oct 23, 2026, 8:09 AM EDT
Not listed Phase 2Phase 3 Interventional Accepts healthy volunteers

Clinical Trial of Tensegrity Prosthetics K3 Promoter Foot Prosthesis

NCT00888199
View directory record Official record
Conditions
Amputation
Interventions
Experimental prosthetic foot (K3 Promoter)
Device
Lead sponsor
Tensegrity Prosthetics
Industry
Eligibility
18 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 27, 2009 · Synced Oct 23, 2026, 8:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Non-Contrast Enhanced Peripheral Magnetic Resonance Angiography

NCT02823444
View directory record Official record
Conditions
Peripheral Arterial Disease, Intermittent Claudication, Peripheral Vascular Disease
Interventions
Magnetic Resonance Angiography
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Oct 23, 2026, 8:09 AM EDT
Completed Not applicable Interventional

DermACELL AWM® in Chronic Wagner Grade 3/4 Diabetic Foot Ulcers

NCT03044132
View directory record Official record
Conditions
Diabetic Foot Ulcer, Lower Extremity Wound
Interventions
DermACELL AWM
Other
Lead sponsor
LifeNet Health
Industry
Eligibility
21 Years to 85 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Fresno, California • Rocky Mount, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Oct 23, 2026, 8:09 AM EDT
Completed No phase listed Observational

Clinical Experience With the Hindfoot Arthrodesis Nail for the Surgical Treatment of Ankle and Hindfoot Pathologies

NCT00942032
View directory record Official record
Conditions
Hindfoot Arthrodesis, Hindfoot Pathologies
Interventions
Not listed
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
Not listed
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
Rancho Mirage, California • Charleston, South Carolina • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 7, 2011 · Synced Oct 23, 2026, 8:09 AM EDT
Completed Phase 2 Interventional

Evaluation of a Folic Acid Wound Treatment (FAWT) for Chronic, Early-Stage Diabetic Foot Ulcer (DFU) Healing

NCT04723134
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Folinic acid calcium salt
Combination Product
Lead sponsor
Joseph Boykin, MD
Federal
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 23, 2026, 8:09 AM EDT
Terminated Phase 4 Interventional Results available

A Clinical Study of Outcomes in Foot and Ankle Bone Grafting Using map3® Cellular Allogeneic Bone Graft

NCT02161016
View directory record Official record
Conditions
Foot Deformities, Acquired, Disorder of Joint of Foot, Fracture of Foot, Deformity of Bone
Interventions
map3
Device
Lead sponsor
RTI Surgical
Industry
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Roslyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 1, 2015 · Synced Oct 23, 2026, 8:09 AM EDT
Not listed Not applicable Interventional

The Omeza Protocol for Chronic Ulcers

NCT04198441
View directory record Official record
Conditions
Venous Leg Ulcer, Diabetic Foot Ulcer
Interventions
Wound dressing
Device
Lead sponsor
Omeza, LLC
Industry
Eligibility
21 Years to 80 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
4
States / cities
Jacksonville, Florida • Newark, New Jersey • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2021 · Synced Oct 23, 2026, 8:09 AM EDT
Completed Not applicable Interventional Results available

AMNIOEXCEL® Plus vs A Marketed Comparator vs SOC in the Management of Diabetic Foot Ulcers

NCT03547635
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
AMNIOEXCEL Plus Amniotic Membrane, A Marketed Comparator, Standard of Care
Other · Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
21 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
7
States / cities
Fresno, California • Los Angeles, California • Gainesville, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Oct 23, 2026, 8:09 AM EDT
Completed No phase listed Observational Results available

ViviGen Cellular Bone Matrix for Hindfoot or Ankle Arthrodesis

NCT04138017
View directory record Official record
Conditions
Ankle Deformity, Ankle Arthritis
Interventions
ViviGen
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 19, 2025 · Synced Oct 23, 2026, 8:09 AM EDT
Completed Not applicable Interventional

Weight Bearing Status Post-hip Arthroscopy

NCT05720806
View directory record Official record
Conditions
Hip Impingement Syndrome, Acetabular Labral Tear
Interventions
Weight Bearing as tolerated (WBAT) immediately following surgery., Flat foot weight bearing (FFWB) immediately following surgery
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 23, 2026, 8:09 AM EDT
Completed Not applicable Interventional Results available

Effect of the Erchonia® EVRL OTC™ for the Relief of Diabetic Peripheral Neuropathy Foot Pain

NCT05091047
View directory record Official record
Conditions
Neuropathy
Interventions
Erchonia EVRL
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Oct 23, 2026, 8:09 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Gondola Mechanism of Action

NCT05146648
View directory record Official record
Conditions
Chronic Stroke, Cerebral Palsy, Parkinson's Disease
Interventions
Gondola AMPS
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 18, 2023 · Synced Oct 23, 2026, 8:09 AM EDT
Recruiting Not applicable Interventional

A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions.

NCT07225751
View directory record Official record
Conditions
Ankle Arthrodesis or Arthroplasty, Hindfoot Fusion, Ankle Deformity, Ankle Disease, Hindfoot Arthrodesis, Hindfoot Pathologies
Interventions
MagnetOs, Autograft
Device · Other
Lead sponsor
Kuros Biosurgery AG
Industry
Eligibility
18 Years to 75 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
7
States / cities
Sacramento, California • Vail, Colorado • Columbus, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 23, 2026, 8:09 AM EDT
Not yet recruiting Not applicable Interventional

PREPUP: A Randomized Trial of Bonvadis® Versus Collagenase Ointment in Diabetic Foot Ulcers

NCT07779239
View directory record Official record
Conditions
Diabetic Foot Ulcers (DFUs)
Interventions
Bonvadis® (NWBOT), Clostridial Collagenase Ointment
Device
Lead sponsor
Oneness Biotech Co., Ltd.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
10
States / cities
North Port, Florida • Palm Coast, Florida • South Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 23, 2026, 8:09 AM EDT
Completed Phase 4 Interventional Results available

Foot and Ankle Clinic Application for Liposomal Related Anesthetic

NCT02586077
View directory record Official record
Conditions
Ankle Arthrodesis, Hindfoot Arthrodesis, Tibitalocalceal Arthrodesis
Interventions
Exparel
Drug
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 29, 2020 · Synced Oct 23, 2026, 8:09 AM EDT
Recruiting Not applicable Interventional

Evaluating the Efficacy of Perinatal Membrane Allografts in Addition to the Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers.

NCT06437028
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Dual-layer perinatal tissue allograft, Three-layer fenestrated perinatal tissue allograft, Standard of care
Other
Lead sponsor
Samaritan Biologics
Industry
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Monroe, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 23, 2026, 8:09 AM EDT