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ClinicalTrials.gov public records Last synced Oct 23, 2026, 9:37 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 673–696 of 1,438 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: PES Clear all
Completed Not applicable Interventional Results available

Adherence and Perspiration While Wearing Lower Limb Prostheses

NCT03900845
View directory record Official record
Conditions
Lower Extremity Amputation
Interventions
Dynamic Air Exchange - Rising Edge Design (DAE-RED), Perforated elastomeric liner, As-prescribed prosthesis
Device
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 23, 2026, 9:37 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Autoimmune Basis for Postural Tachycardia Syndrome

NCT02725060
View directory record Official record
Conditions
Postural Orthostatic Tachycardia Syndrome, Postural Tachycardia Syndrome, Tachycardia, Arrhythmias, Cardiac, Autonomic Nervous System Diseases, Orthostatic Intolerance, Cardiovascular Diseases, Primary Dysautonomias
Interventions
phenylephrine, isoproterenol, 25 micro-Ci of radiation, Posture study with blood samples, 24-hour heart rhythm and blood pressure monitoring, Quantitative Axonal Sudomotor Reflex Testing, Autonomic function tests, Rebreathing test, Assessment of splanchnic capacitance, microneurography
Drug · Radiation · Procedure + 1 more
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
2
States / cities
Oklahoma City, Oklahoma • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 23, 2026, 9:37 AM EDT
Withdrawn Not applicable Interventional

A Cataract Surgery Clinical Trial

NCT07044674
View directory record Official record
Conditions
Cataract
Interventions
UNITY Vitreoretinal Cataract System, CENTURION Vision System with Active Sentry, Anterior segment ophthalmic surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
5
States / cities
West Des Moines, Iowa • Sioux Falls, South Dakota • Spring, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 23, 2026, 9:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Measures of Gait Efficiency of Three Multi-Axial, Vertical Shock and Energy Storing-Return Prosthetic Feet During Simple & Complex Mobility Activities

NCT01404559
View directory record Official record
Conditions
Amputation
Interventions
Ossur Variflex prosthetic foot, Ossur Ceterus prosthetic foot, Endolite Elite Blade prosthetic foot
Device
Lead sponsor
University of South Florida
Other
Eligibility
21 Years to 45 Years · Male only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 15, 2014 · Synced Oct 23, 2026, 9:37 AM EDT
Recruiting Not applicable Interventional

Inclined Versus Standard Exercise for COPD Patients

NCT06749262
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
walking on incline or walking at increasing speed for 36 visits
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 23, 2026, 9:37 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Metabolic Cost Savings for Transtibial Amputees Wearing the Controlled Energy Storage and Return (CESR) Foot

NCT00494143
View directory record Official record
Conditions
Transtibial Amputation
Interventions
CESR Prosthetic Foot, typical prosthetic foot, standardized prosthetic foot
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 9, 2014 · Synced Oct 23, 2026, 9:37 AM EDT
Completed Phase 3 Interventional

Efficacy and Safety Study of 4975 to Manage Pain of Bunionectomy

NCT00656578
View directory record Official record
Conditions
Pain
Interventions
4975, Placebo
Drug
Lead sponsor
Anesiva, Inc.
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
6
States / cities
Bakersfield, California • Owings Mills, Maryland • Austin, Texas + 3 more
Source: ClinicalTrials.gov public record
Updated May 4, 2009 · Synced Oct 23, 2026, 9:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Correlation Between Central Sensitization Inventory and Posturographic Data

NCT03058003
View directory record Official record
Conditions
Central Nervous System Sensitization
Interventions
Posturography Evaluation, Central Sensitization Inventory
Diagnostic Test · Other
Lead sponsor
Caps Research Network
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 23, 2026, 9:37 AM EDT
Active, not recruiting No phase listed Observational

JuggerKnot With Broadband PMCF Study

NCT05762588
View directory record Official record
Conditions
Shoulder Injuries, Hip Injuries, Foot Injury, Ankle Injuries, Knee Injuries
Interventions
Juggerknot with Broadband tape
Device
Lead sponsor
Riverpoint Medical
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Hyattsville, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 23, 2026, 9:37 AM EDT
Completed Phase 2 Interventional Results available

Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Pain Associated With Diabetic Neuropathy

NCT02068027
View directory record Official record
Conditions
Painful Diabetic Neuropathy, Diabetic Neuropathy, Neuropathy
Interventions
Clonidine Gel 0.1%, Placebo
Drug
Lead sponsor
BioDelivery Sciences International
Industry
Eligibility
18 Years to 85 Years
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
23
States / cities
Phoenix, Arizona • Santa Monica, California • Walnut Creek, California + 20 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2017 · Synced Oct 23, 2026, 9:37 AM EDT
Completed Not applicable Interventional

Study of Subtalar Arthrodesis Using AlloStem® Versus Autologous Bone Graft

NCT01413061
View directory record Official record
Conditions
Degenerative Osteoarthritis, Post-traumatic; Arthrosis, Rheumatoid Arthritis & Other Inflammatory Polyarthropathies, Rheumatoid Arthritis of Subtalar Joint
Interventions
Subtalar Arthrodesis
Procedure
Lead sponsor
AlloSource
Industry
Eligibility
18 Years to 80 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
5
States / cities
Baltimore, Maryland • Grand Rapids, Michigan • Edina, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2018 · Synced Oct 23, 2026, 9:37 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Dose Finding Study In Subjects With Crow's Feet

NCT01951742
View directory record Official record
Conditions
Lateral Canthal Lines, Crow's Feet
Interventions
ANT-1401, Vehicle
Biological
Lead sponsor
Anterios Inc.
Industry
Eligibility
30 Years to 60 Years
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
10
States / cities
Miami, Florida • Pinellas Park, Florida • West Palm Beach, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated May 29, 2014 · Synced Oct 23, 2026, 9:37 AM EDT
Recruiting Not applicable Interventional

Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Diabetic Foot Ulcers

NCT07039396
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
NeoThelium FT (HCT/P 361)
Other
Lead sponsor
NuScience Medical Biologics, LLC
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
3
States / cities
Alexandria, Louisiana • Leesville, Louisiana • Many, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 23, 2026, 9:37 AM EDT
Enrolling by invitation Phase 4 Interventional

Mepivacaine Versus Bupivacaine Onset Time in Ultrasound-guided Ankle Blocks

NCT05425979
View directory record Official record
Conditions
Ankle Block, Foot Surgery
Interventions
Mepivacaine, Bupivacaine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 23, 2026, 9:37 AM EDT
Withdrawn No phase listed Observational

Investigation of the Use of Hyperspectral Imaging in Foot Surgery Patients

NCT03787862
View directory record Official record
Conditions
Foot Ulcers, Osteomyelitis, Amputation
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 26, 2018 · Synced Oct 23, 2026, 9:37 AM EDT
Completed Not applicable Interventional Results available

Larval Debridement Therapy Versus Sharp Debridement to Remove Biofilm

NCT02294175
View directory record Official record
Conditions
Lower Extremity or Diabetic Foot Ulcers, Bacterial Infection
Interventions
Larval Debridement Therapy, Bedside Sharp Debridement
Device · Procedure
Lead sponsor
North Florida Foundation for Research and Education
Other
Eligibility
21 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 23, 2026, 9:37 AM EDT
Completed Not applicable Interventional

Phase IV Study to Evaluate the Efficacy of AMNIOEXCEL in Diabetic Foot Ulcers

NCT02209051
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
AMNIOEXCEL, Standard of Care, Diabetic Foot Ulcers
Other
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
8
States / cities
Phoenix, Arizona • Castro Valley, California • Stockton, California + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2017 · Synced Oct 23, 2026, 9:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Characterizing Ankle Function During Sloped Locomotion for Prosthesis Development

NCT01784003
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Powered ankle-foot prosthesis
Device
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 10, 2020 · Synced Oct 23, 2026, 9:37 AM EDT
Terminated Not applicable Interventional

Health Economic Assessment of Lower Extremity Diabetic (HEALED) Ulcers With PriMatrix

NCT01729286
View directory record Official record
Conditions
Foot Ulcer, Diabetic
Interventions
PriMatrix Moist Wound Therapy, Standard of Care Moist Wound Therapy
Device · Other
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
15
States / cities
Los Angeles, California • Miami, Florida • Tampa, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Oct 23, 2026, 9:37 AM EDT
Active, not recruiting Phase 4 Interventional

Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE

NCT03581877
View directory record Official record
Conditions
Pulmonary Embolism, Pulmonary Hypertension, Thromboembolism, Right Ventricular Dysfunction
Interventions
Alteplase, EKOS
Drug · Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 89 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Bay Shore, New York • Queens, New York
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 23, 2026, 9:37 AM EDT
Active, not recruiting Not applicable Interventional

C-Brace II Spinal Cord Injury

NCT03930056
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
C-Brace II, Traditional Care KAFO intervention
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 23, 2026, 9:37 AM EDT
Not listed Phase 1Phase 2 Interventional

Diabetic Neuropathic Pain Relief, 6 Weeks Dosage Sublingual Water-soluble CBD/PEA

NCT05766969
View directory record Official record
Conditions
Diabetic Peripheral Neuropathic Pain
Interventions
CBD/PEA, Placebo
Drug
Lead sponsor
Pure Green Pharmaceuticals Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Southfield, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Oct 23, 2026, 9:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Clinical Comparison of Length of Cataract Procedures With Zeiss Lumera Versus Older Zeiss Microscope

NCT03298841
View directory record Official record
Conditions
Cataract
Interventions
Zeiss
Device
Lead sponsor
Toyos Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Oct 23, 2026, 9:37 AM EDT
Terminated Phase 2 Interventional Results available

Topical Tazarotene Vs Placebo In Hand-Foot-Skin Reactions

NCT04071756
View directory record Official record
Conditions
Solid Tumor, Hand-Foot Skin Reaction (HFSR)
Interventions
Topical Tazarotene, Placebo
Drug · Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Oct 23, 2026, 9:37 AM EDT