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ClinicalTrials.gov public records Last synced Oct 24, 2026, 3:10 PM EDT

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Showing 1009–1032 of 1,438 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: PES Clear all
Completed Not applicable Interventional Results available

Multi-layer Insoles for a Patient-specific Approach to Shear and Pressure Reduction in Diabetes-related Foot Ulcer

NCT01844479
View directory record Official record
Conditions
Diabetic Foot Ulcer, Diabetic Foot
Interventions
diabetic foot orthotic, Standard innersole
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Oct 24, 2026, 3:10 PM EDT
Not listed Not applicable Interventional

Sinus Tarsi Versus Extensile Lateral Approach for Calcaneus Fractures

NCT02446470
View directory record Official record
Conditions
Intra-articular Fractures
Interventions
Sinus Tarsi approach, Extensile Lateral approach
Procedure
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Oct 24, 2026, 3:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Reiki, Yoga, Meditation, on the Physical and Psychological Symptoms of Chemotherapy-Induced Peripheral Neuropathy

NCT01569269
View directory record Official record
Conditions
Peripheral Neuropathy
Interventions
Yoga Intervention, Meditation Intervention, Reiki, Holistic Education
Behavioral · Other
Lead sponsor
George Mason University
Other
Eligibility
18 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2012 · Synced Oct 24, 2026, 3:10 PM EDT
Suspended Phase 2 Interventional

A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Onychomycosis

NCT05491603
View directory record Official record
Conditions
Onychomycosis
Interventions
DBI-001, DBI-002, Aqueous Gel
Biological
Lead sponsor
DermBiont, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
5
States / cities
Encino, California • New Brighton, Minnesota • Portland, Oregon + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced Oct 24, 2026, 3:10 PM EDT
Completed No phase listed Observational

Pulse Oximetry and Skin Pigmentation - Peds

NCT05185427
View directory record Official record
Conditions
Pulse Oximetry
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
Up to 17 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 10, 2024 · Synced Oct 24, 2026, 3:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Swab Sample Collection for the Detection of Bacterial Proteases in Wounds Assay

NCT01750203
View directory record Official record
Conditions
Chronic Wounds With Different Etiologies
Interventions
Swabs
Other
Lead sponsor
Systagenix Wound Management
Industry
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 20, 2012 · Synced Oct 24, 2026, 3:10 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Intrinsic Foot Muscle Strengthening Interventions for Older Adults

NCT05829369
View directory record Official record
Conditions
Accidental Fall
Interventions
Intrinsic foot muscle strengthening exercises, Minimal footwear with prescribed walking, Control
Other
Lead sponsor
Springfield College
Other
Eligibility
65 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Oct 24, 2026, 3:10 PM EDT
Completed Not applicable Interventional

RESTIFFIC™ Foot Wrap Reduces Moderate to Severe Restless Leg Syndrome

NCT02386423
View directory record Official record
Conditions
Restless Leg Syndrome
Interventions
RESTIFFIC™ Brand Pressure Application System
Device
Lead sponsor
Lake Erie Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Erie, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 11, 2015 · Synced Oct 24, 2026, 3:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

An Evaluation Of Healthy Ankle Motion And Morphology

NCT03619382
View directory record Official record
Conditions
Healthy Ankle
Interventions
Cone Beam Computed Tomography, Radiographs
Radiation
Lead sponsor
Paragon 28
Industry
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Atlantis, Florida
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Oct 24, 2026, 3:10 PM EDT
Enrolling by invitation No phase listed Observational

Clinical Registry Collecting Real World Evidence on Wound Care Treatments

NCT06328010
View directory record Official record
Conditions
Wounds and Injuries, Burns, Mohs Surgery, Diabetic Foot Ulcer Mixed, Venous Leg Ulcer, Non-healing Wound, Trauma Injury, Injury and Wounds, Degloving Injuries, Pressure Ulcers, Bedsores, Decubitus Ulcer
Interventions
Various types of wound care treatments
Combination Product
Lead sponsor
Siddhey LLC
Industry
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
12
States / cities
Scottsdale, Arizona • Tempe, Arizona • Tucson, Arizona + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 24, 2026, 3:10 PM EDT
Completed Not applicable Interventional

Comparison of Various Prosthetic Foot-Ankle Mechanisms

NCT05964855
View directory record Official record
Conditions
Transtibial Amputation - Unilateral
Interventions
MIT Variable Stiffness Prosthesis v1, MIT Variable Equilibrium Angle Prosthesis v1, MIT Sliding Beam Passive Prosthesis, Ossur Pro-Flex XC, Blatchford Elan Variable-Dampening Prosthesis, Ossur Proprio Variable Angle Prosthesis, MIT Variable Stiffness Prosthesis v2, MIT Variable Equilibrium Angle Prosthesis v2
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Burlington, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 24, 2026, 3:10 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Pre-post Spinal Popliteal Block

NCT05354791
View directory record Official record
Conditions
Foot Surgery, Ankle Surgery
Interventions
Not listed
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
Not listed
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 1, 2024 · Synced Oct 24, 2026, 3:10 PM EDT
Recruiting Not applicable Interventional

Wearable Technology to Characterize and Treat mTBI Subtypes: Biofeedback-Based Precision Rehabilitation

NCT06381674
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Concussion, Rehabilitation, Balance Impairment
Interventions
Vestibular therapy for mTBI augmented with audio and visual real-time biofeedback, Vestibular therapy for mTBI
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Portland, Oregon • San Antonio, Texas • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 24, 2026, 3:10 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Onabotulinum Toxin Type A and Abobotulinum Toxin Type A Crow's Feet Rhytid Study

NCT01529788
View directory record Official record
Conditions
Intrinsic Aging of Skin, Solar Elastosis
Interventions
Right lateral orbital injection of Botox Cosmetic or Dysport, Left lateral orbital injection of Botox Cosmetic or Dysport
Drug
Lead sponsor
The Maas Clinic
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2014 · Synced Oct 24, 2026, 3:10 PM EDT
Not listed Phase 2 Interventional

A Novel Approach to Plantar Fasciitis in the Aging Population

NCT05834491
View directory record Official record
Conditions
Plantar Fasciitis, Chronic
Interventions
minimal shoes and foot strengthening and flexibility exercises, Supportive Footwear, foot orthotic device and foot flexibility exercises
Device
Lead sponsor
University of South Florida
Other
Eligibility
50 Years to 70 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 24, 2026, 3:10 PM EDT
Recruiting Phase 3 Interventional

Safety and Efficacy Study of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults With Moderate or Severe Diabetic Foot Infections (DFI)

NCT05369052
View directory record Official record
Conditions
Diabetic Foot Infection
Interventions
contezolid acefosamil (IV)/contezolid (PO), Linezolid (IV and PO)
Drug
Lead sponsor
MicuRx
Industry
Eligibility
18 Years and older
Enrollment
865 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Corona, California • Vista, California
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 24, 2026, 3:10 PM EDT
Terminated Not applicable Interventional Results available

Prevention of Delirium After Bone Marrow Transplantation

NCT01700816
View directory record Official record
Conditions
Delirium
Interventions
Bright light therapy, Sham light
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Oct 24, 2026, 3:10 PM EDT
Completed Not applicable Interventional Results available

iStride(TM) Device Used for Stroke Rehabilitation

NCT02185404
View directory record Official record
Conditions
Stroke
Interventions
wearing the iStride device
Device
Lead sponsor
University of South Florida
Other
Eligibility
21 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Oct 24, 2026, 3:10 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Influence of Lumbar Ultrasound on Resident Learning Curve for Lateral Labor Epidural Placement

NCT02826668
View directory record Official record
Conditions
Labor Epidural, Lumbar Ultrasound
Interventions
Ultrasound
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 24, 2026, 3:10 PM EDT
Completed Not applicable Interventional

Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers

NCT01693133
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Standard of Care: Moist Wound Therapy and Offloading, EpiFix plus Standard of Care
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
20
States / cities
Birmingham, Alabama • Bakersfield, California • Castro Valley, California + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Oct 24, 2026, 3:10 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

High-Intensity Interval Training for Older Adults

NCT05542758
View directory record Official record
Conditions
Age-Related Sarcopenia
Interventions
Total Body HIIT Program
Other
Lead sponsor
Creighton University
Other
Eligibility
65 Years to 95 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 16, 2024 · Synced Oct 24, 2026, 3:10 PM EDT
Completed Not applicable Interventional

Diabetic Foot Ulcers-Comparing Transforming Powder to Standard of Care

NCT05046158
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Transforming Powder Dressing, Standard of care topical wound agents and dressings
Device · Other
Lead sponsor
ULURU Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
12
States / cities
Washington D.C., District of Columbia • Winter Park, Florida • Baltimore, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Oct 24, 2026, 3:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of OMM on Anandamide Levels in Saliva

NCT02727023
View directory record Official record
Conditions
Anandamide, Endocannabinoids
Interventions
Osteopathic Manipulative Medicine
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Oct 24, 2026, 3:10 PM EDT
Recruiting Not applicable Interventional

From Opinion to Evidence: Multi-site Evaluation of Custom Dynamic Orthosis Best Practices

NCT06352788
View directory record Official record
Conditions
Foot Injury
Interventions
Modular Carbon Fiber Custom Dynamic Orthosis (CDO), Mono Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
Jason Wilken
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
5
States / cities
San Diego, California • Iowa City, Iowa • Minneapolis, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 24, 2026, 3:10 PM EDT