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ClinicalTrials.gov public records Last synced Oct 27, 2026, 2:23 PM EDT

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Showing 1009–1032 of 1,259 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: PLAY Clear all
Completed Phase 2 Interventional

A Phase II Randomized Controlled Trial to Determine the Efficacy of an auGmented reAlity gaMe in pediatrIc caNcer Patients Who Are Opioid Naïve Undergoing Surgery to Reduce Postoperative Opioid Use (GAMING-ON Study)

NCT05466994
View directory record Official record
Conditions
Pediatric ALL, Cancer
Interventions
IPAD, Augmented Reality
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
5 Years to 15 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 27, 2026, 2:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Noninvasive Physiologic Sensors to Assess Depression

NCT02568865
View directory record Official record
Conditions
Depression, Major Depressive Disorder
Interventions
Physiological Sensors, Sleep Monitoring Device, Vocal Monitoring, Mobile Phone
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 25, 2020 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Autism Adaptive Community-based Treatment to Improve Outcomes Using Navigators (ACTION) Network

NCT03575429
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Engagement Intervention, Engagement + Coaching Intervention
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
12 Months to 24 Months
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
3
States / cities
Coral Gables, Florida • Tallahassee, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

The Medical College of Georgia PLAY Project: Exercise Dose and Insulin Sensitivity in Obese Children

NCT00108901
View directory record Official record
Conditions
Obesity, Type 2 Diabetes Prevention, Executive Function (Cognition)
Interventions
Aerobic exercise program
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
7 Years to 11 Years
Enrollment
222 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 24, 2014 · Synced Oct 27, 2026, 2:23 PM EDT
Not listed Phase 2 Interventional

A Single Ketamine Infusion Combined With Music for Suicidal Ideation

NCT04658420
View directory record Official record
Conditions
Suicidal Ideation, Depressive Episode
Interventions
Ketamine Hydrochloride, Music
Drug · Other
Lead sponsor
The University of Texas Health Science Center at Tyler
Other
Eligibility
18 Years to 64 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tyler, Texas
Source: ClinicalTrials.gov public record
Updated May 7, 2021 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional

Animal-Assisted Interactions in Children With Life-Threatening Conditions and Their Parents

NCT03765099
View directory record Official record
Conditions
Advanced Cancer, Relapsed Cancer, Refractory Cancer
Interventions
Animal-Assisted Interactions
Behavioral
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
3 Years to 17 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 23, 2023 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Digital Intervention to Prevent Initiation of Opioid Misuse in Adolescents in School-based Health Centers

NCT04109599
View directory record Official record
Conditions
Opioid Misuse
Interventions
PlaySmart, PlaySmart Storyline, Play Smart Mini-Game
Behavioral
Lead sponsor
Yale University
Other
Eligibility
16 Years to 19 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Exposure-Based Implementation Strategy to Decrease Clinician Anxiety Around Suicide Prevention

NCT05172609
View directory record Official record
Conditions
Implementation Science
Interventions
Exposure Based Implementation Strategy (EBIS), Implementation as Usual (IAU)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neuroendocrine and Immune Response to Stress in Schizophrenia

NCT01975584
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Trier Social Stress Test
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 64 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 27, 2019 · Synced Oct 27, 2026, 2:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study

NCT06995638
View directory record Official record
Conditions
Healthy Aging, Alzheimer's Disease (AD)
Interventions
Web-based Cognitive Training (with strategy), Web-based Cognitive Training (without strategy)
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
60 Years to 75 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 27, 2026, 2:23 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Dynamic Vision Testing and Concussion Management Dream Team 65

NCT05326555
View directory record Official record
Conditions
Head Injury, Sport Injury, Concussion, Brain
Interventions
Dynamic Vision Testing (Bertec Vision Advantage System) and Balance Error Scoring System
Diagnostic Test
Lead sponsor
California State University, Northridge
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Northridge, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2022 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Social Motivation Intervention for Children With Autism Spectrum Disorder: Improving Peer Initiation

NCT02360449
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Social Initiation Motivation Intervention
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
4 Years to 6 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 8, 2021 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Palatal Donor Site Wound Healing Following Periodontal Plastic Surgery Using Amnion-Chorion Membrane

NCT05927714
View directory record Official record
Conditions
Palate; Wound
Interventions
Amnion-chorion Membrane, ActCel Cellulose Gauze
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 89 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional

Examining the Effects of Video-game Exercise on Mobility and Brain Plasticity in Individuals With Multiple Sclerosis

NCT01780792
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Dance Dance Revolution video game play
Other
Lead sponsor
Ohio State University
Other
Eligibility
30 Years to 59 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2017 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional Results available

Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy for Patients With Knee Osteoarthritis

NCT04187092
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
KneeBright Group, Standard Rehabilitation group
Other
Lead sponsor
University of Virginia
Other
Eligibility
40 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing a Shortened Version of the AlAn's Game

NCT03834467
View directory record Official record
Conditions
Psychopathic Personality Trait
Interventions
Arm 1 - Elevation Stimulus Video, Arm 2 - Control Stimulus Video
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 25 Years
Enrollment
537 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 19, 2020 · Synced Oct 27, 2026, 2:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Music Therapy Study for Blood Cancer Survivors With Cognitive Difficulties

NCT07052916
View directory record Official record
Conditions
Blood Cancer, Lymphoma, Leukemia, Myeloma
Interventions
Music Therapy/MT, Therapist-Attention Music Education/TAME Control
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Accessible Digital Intervention to Promote HIV Testing/Counseling and Prevention Among Adolescents

NCT03713034
View directory record Official record
Conditions
HIV Prevention
Interventions
PlayTest!, Control games
Other
Lead sponsor
Yale University
Other
Eligibility
14 Years to 18 Years
Enrollment
296 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HIV Prevention Intervention for Young Transgender Women

NCT01575938
View directory record Official record
Conditions
Sexual Transmission of Infection
Interventions
HIV prevention intervention, Diet and Nutrition
Behavioral
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
16 Years to 29 Years · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
2
States / cities
Chicago, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Oct 27, 2026, 2:23 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Promoting Playfulness

NCT06625255
View directory record Official record
Conditions
Developmental Delay (Disorder)
Interventions
Parent Education - Promoting Playfulness
Behavioral
Lead sponsor
Florida Gulf Coast University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Fort Myers, Florida
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Music Therapy and Social Work Telehealth for Older Adult Well-Being

NCT06219148
View directory record Official record
Conditions
Aging Well, Dementia, Telemedicine
Interventions
Music Therapy Telehealth, Non-Collaborative Social Work Telehealth, Collaborative Social Work Telehealth
Behavioral
Lead sponsor
Alaine E Hernandez, PhD
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Lexington, Kentucky • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Oct 27, 2026, 2:23 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Covid-19 Long Haul Preventative and Health Promotion Care Clinical Trial Acceleration Program.

NCT06441955
View directory record Official record
Conditions
COVID-19, Long Haul
Interventions
Ritonavir-Boosted Nirmatrelvir (Paxlovid), Physiological Evaluation, Moderna COVID-19 Vaccine, Biopsychological, Behavioral (e.g., Psychotherapy, Lifestyle Counseling), Genetic (including gene transfer, stem cell and recombinant DNA), Multidisciplinary approach
Drug · Diagnostic Test · Biological + 3 more
Lead sponsor
Well- Konnect Healthcare Services and Research Firm
Network
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 27, 2024 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional

'Food, Fun, Fresh, Family' Program for Healthy Eating and Growth for Elementary-age Children.

NCT06010784
View directory record Official record
Conditions
Diet, Healthy Growth
Interventions
Family support, BGCAA's after-school program with CATCH curriculum
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
5 Years to 11 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 27, 2026, 2:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Motivation to Exercise

NCT02444247
View directory record Official record
Conditions
Overweight, Obesity, Physical Activity
Interventions
High Dose Exercise (300 kcal), Low Dose Exercise (150 kcal), No Exercise (0 kcal), Sedentary Option
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
18 Years to 49 Years
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Apr 11, 2025 · Synced Oct 27, 2026, 2:23 PM EDT