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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–66 of 66 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: PP Clear all
Recruiting Not applicable Interventional

Promoting Well-being and Health in Heart Failure

NCT04829617
View directory record Official record
Conditions
Heart Failure, Heart Failure NYHA Class I, Heart Failure NYHA Class II, Heart Failure NYHA Class III
Interventions
PP-MI Intervention, MI-alone Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 20, 2026, 2:52 AM EDT
Active, not recruiting Not applicable Interventional

Diet and Health in Adults With Metabolic Syndrome

NCT03935048
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Higher protein, low glycemic load diet
Dietary Supplement
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
18 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Oct 20, 2026, 2:52 AM EDT
Completed Not applicable Interventional Results available

A Psychological-behavioral Intervention for Physical Activity in Type 2 Diabetes

NCT03150199
View directory record Official record
Conditions
Type2 Diabetes
Interventions
Positive Psychology + Motivational Interviewing, MI-based Health Education Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Oct 20, 2026, 2:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh

NCT06409091
View directory record Official record
Conditions
Hernia, Ventral, Hernia Incisional
Interventions
Medium weight or Heavy weight mesh
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
1,496 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 14, 2024 · Synced Oct 20, 2026, 2:52 AM EDT
Enrolling by invitation No phase listed Observational

Wearables to Define Postpartum Blood Pressure Trajectories and Facilitate Evidence-based Monitoring Guidelines

NCT06576544
View directory record Official record
Conditions
Hypertension, Pregnancy-Induced, Hypertension, Postpartum Preeclampsia, Postpartum Complication, Postpartum Pre-Eclampsia, Cardiovascular Diseases, Cardiovascular Morbidity, Morbidity;Perinatal
Interventions
BP Watch
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 20, 2026, 2:52 AM EDT
Completed Not applicable Interventional Results available

A Psychological-behavioral Intervention to Increase Activity in Type 2 Diabetes

NCT03164538
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Positive Psychology + Motivational Interviewing, Diabetes Education
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Oct 20, 2026, 2:52 AM EDT
Completed Not applicable Interventional

A Tailored Program to Promote Well-being and Physical Activity in Mid-life Adults With Low Physical Activity

NCT04745182
View directory record Official record
Conditions
Middle Aged, Exercise
Interventions
MASTERY
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years to 64 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Oct 20, 2026, 2:52 AM EDT
Terminated Phase 2 Interventional Results available

Safety & Efficacy of Eculizumab to Prevent AMR in Living Donor Kidney Transplant Recipients Requiring Desensitization

NCT01399593
View directory record Official record
Conditions
Antibody Mediated Rejection
Interventions
Eculizumab
Drug
Lead sponsor
Alexion Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
17
States / cities
Birmingham, Alabama • La Jolla, California • Los Angeles, California + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2017 · Synced Oct 20, 2026, 2:52 AM EDT
Completed Phase 2 Interventional Results available

A Study Investigating Long-term Treatment With Spesolimab in People With a Skin Disease Called Hidradenitis Suppurativa Who Completed a Previous Clinical Trial

NCT04876391
View directory record Official record
Conditions
Hidradenitis Suppurativa
Interventions
Spesolimab 1200 mg, Spesolimab 600 mg, Placebo matching 600 mg Spesolimab, Placebo matching 1200 mg Spesolimab
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
4
States / cities
Los Angeles, California • Indianapolis, Indiana • Rochester, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 20, 2026, 2:52 AM EDT
Completed Phase 1 Interventional

Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.

NCT00423254
View directory record Official record
Conditions
Ovarian, Melanoma, Renal, Prostate, Colorectal, Endometrial Carcinoma, Cervical Carcinoma, Testicular Cancer, Thyroid Cancer, Small Cell Lung Carcinoma, Mesothelioma, Breast Carcinoma, Esophageal Carcinoma, Gastric Cancer, Pancreatic Carcinoma, Neuroendocrine Cancer, Liver Cancer, Gallbladder Cancer, Biliary Tract Cancer, Anal Carcinoma, Bone Sarcomas, Soft Tissue Sarcomas, Carcinoma of Unknown Origin, Primary
Interventions
PSMA/PRAME
Biological
Lead sponsor
Mannkind Corporation
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
5
States / cities
Tuscon, Arizona • Washington D.C., District of Columbia • Tampa, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2010 · Synced Oct 20, 2026, 2:52 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

A Study to Learn About How the Flu and COVID-19 Vaccines Act in Healthy People

NCT06821061
View directory record Official record
Conditions
Influenza, COVID-19 (Coronavirus Disease 2019)
Interventions
Investigational Influenza Vaccine, Investigational COVID-19 Vaccine, Investigational Influenza and COVID-19 Combination Vaccine, Licensed Influenza Vaccine 1, Licensed Influenza Vaccine 2, Licensed Influenza Vaccine 3, Licensed COVID-19 Vaccine
Biological · Combination Product
Lead sponsor
BioNTech SE
Industry
Eligibility
18 Years and older
Enrollment
2,650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
31
States / cities
Anaheim, California • Lake Forest, California • Riverside, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 20, 2026, 2:52 AM EDT
Completed Phase 1 Interventional Results available

Text Messaging to Increase Activity in Midlife

NCT04849052
View directory record Official record
Conditions
Middle Aged
Interventions
MASTERY, Attentional Control
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years to 64 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 20, 2026, 2:52 AM EDT
Completed Not applicable Interventional

Positive Psychology for ACS Patients: a Factorial Design Study

NCT02754895
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Positive Psychology (PP), Motivational Interviewing (MI)
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 1, 2017 · Synced Oct 20, 2026, 2:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Positive Prevention PLUS Program

NCT02540278
View directory record Official record
Conditions
Pregnancy in Adolescence
Interventions
Positive Prevention PLUS
Behavioral
Lead sponsor
California State University, San Bernardino
Other
Eligibility
12 Years to 19 Years
Enrollment
4,267 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Bernardino, California
Source: ClinicalTrials.gov public record
Updated Sep 3, 2015 · Synced Oct 20, 2026, 2:52 AM EDT
Completed Not applicable Interventional

Boosting Emotions & Happiness in Outpatients Living With Diabetes: Phase I

NCT03001999
View directory record Official record
Conditions
Type 2 Diabetes, Emotions, Patient Compliance
Interventions
PP-MI health behavior intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 20, 2026, 2:52 AM EDT
Completed Not applicable Interventional

Piloting Text Messages to Promote Positive Affect and Physical Activity

NCT04077229
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Intervention arm: Text Message Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 21, 2020 · Synced Oct 20, 2026, 2:52 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

The PPCGMS Intervention After GDM Trial

NCT06057805
View directory record Official record
Conditions
Postpartum Gestational Diabetes Mellitus
Interventions
Blinded Dexcom G7 CGM
Device
Lead sponsor
Woman's
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 18, 2024 · Synced Oct 20, 2026, 2:52 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care

NCT05415761
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
iCanQuit, iCanQuit+Motiv8, Florida quit line
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years and older
Enrollment
1,332 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 20, 2026, 2:52 AM EDT