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ClinicalTrials.gov public records Last synced Oct 21, 2026, 3:19 AM EDT

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Showing 913–936 of 1,548 matching trials from the local directory fallback.

Filters: Intervention: PRE Clear all

Conditions: Depression, Hearing Disability, Mobility Disability
Interventions: Sham Digital Program - General health education and interactive quizzes unrelated to depression or CBT., Toivoa-002 - A digital Cognitive Behavioral Therapy program combined with NBHWC-certified coaching.; Device
Lead sponsor: Toivoa Inc; Industry
Eligibility: 22 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 4
States / cities: Dover, Delaware • East Orange, New Jersey • Cleveland, Ohio + 1 more

Conditions: Gastroesophageal Reflux Disease, Refractory Gastroesophageal Reflux Disease
Interventions: Fosamprenavir Calcium 700 MG Oral Tablet, Placebo; Drug · Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 50 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Gingival Recession
Interventions: Gum Graft Placed on Denuded Bone, Gum Graft Placed on Split Thickness Periosteal Bed Preparation; Procedure
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 95 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2028 – 2031
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: ASCVD, Hyperlipidemia, Hypertension
Interventions: Referral to the Duke Cardiometabolic Prevention Clinic; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Chronic Low Back Pain
Interventions: DHEA, Placebo, Pregnenolone; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Opioid Induced Respiratory Depression, Post Surgical Respiratory Failure, Respiratory Arrest, Respiratory Complication
Interventions: Linshom Continuous Predictive Respiratory Monitoring; Device
Lead sponsor: Linshom Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 394 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Baltimore, Maryland • Columbus, Ohio

Conditions: Breast Cancer
Interventions: Frequently Asked Questions Exposure, Risk Presentation Format; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 39 Years to 74 Years · Female only
Enrollment: 3,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Knee Arthroplasty, Total
Interventions: Bupivacaine, Clonidine, Epinephrine, Buprenorphine and Dexamethasone (BPV-CEBD) Combination, Liposomal Bupivacaine; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Depression
Interventions: Enhanced Usual Care (EUC), Supported Online Self-help for Depression (SOS-Depression); Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: San Diego, California • West Los Angeles, California

Conditions: Degenerative Spine Disease, Spinal Stenosis Lumbar
Interventions: CBT Prehabilitation without Virtual Reality, Virtual Reality-Based CBT Prehabilitation (VR-CBT); Behavioral
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years to 75 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Irvine, California • Newport Beach, California

Conditions: Alcohol Use Disorder (AUD), Major Depressive Disorder (MDD)
Interventions: Placebo, Pregnenolone; Drug
Lead sponsor: Sherwood Brown, MD, PhD; Other
Eligibility: 21 Years to 55 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 2
States / cities: Dallas, Texas • Richardson, Texas

Conditions: Noise-Induced Hearing Loss
Interventions: Diabetes prevention program & delayed TC, Talking Circle; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2030
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: HIV Prevention, Latino Men Who Have Sex With Men, Pharmacy
Interventions: CVS Health brochure, PrEP & Soccer PrEP Navigation; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 54 Years · Male only
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Cardiogenic Shock, Heart Failure, Inflammation
Interventions: Methylprednisone, Standard of Care (SOC); Drug · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Anxiety Disorders, Autism Spectrum Disorder, Depressive Disorder
Interventions: CBT-DAY (Cognitive Behavioral Therapy for Depression in Autistic Youth), Treatment-as-Usual (TAU); Behavioral
Lead sponsor: Children's Hospital Los Angeles; Other
Eligibility: 11 Years to 17 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: GERD, Gastroesophageal Reflux, Heartburn, Hiatal Hernia, Paraesophageal Hernia
Interventions: Preoperative workup without high-resolution esophageal manometry, Standard preoperative workup with high-resolution esophageal manometry; Procedure
Lead sponsor: McMaster University; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Food Insecurity, Hypertension (HTN)
Interventions: Community Health Worker navigated Produce Prescription, Produce Prescription Only; Behavioral
Lead sponsor: University of Hawaii; Other
Eligibility: 20 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 3
States / cities: Honokaa, Hawaii • Waianae, Hawaii • Waimanalo, Hawaii

Conditions: HIV Prevention
Interventions: Education and Mentoring for Prescribing Pharmacists; Other
Lead sponsor: Xavier University of Louisiana.; Other
Eligibility: 24 Years to 99 Years
Enrollment: 75 participants
Timeline: 2027 – 2030
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Developmental Disability, Intellectual Disabilities
Interventions: Comprehensive Community Health, Regular Special Olympics programming; Behavioral · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 21 Years to 65 Years
Enrollment: 1,040 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Emotion Regulation, Executive Functioning, Self-injury, Suicidal Ideation and Behavior
Interventions: Preadolescent SITB Intervention, Treatment as usual (TAU); Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 7 Years to 12 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Family Caregivers, Psychological Support, Rett Syndrome, Social Support
Interventions: Caregiver Speaks + Daybue, Those who have patients prescribed Daybue; Other
Lead sponsor: Colorado State University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Fort Collins, Colorado

Conditions: Predictive Modeling
Interventions: Risk Prediction Model; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 65 Years and older
Enrollment: 18,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Diffuse Large B-Cell Lymphoma, Grade 3b Follicular Lymphoma, High Grade B-Cell Lymphoma, Primary Mediastinal Large B-Cell Lymphoma, Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: Biospecimen Collection, Computed Tomography, Cyclophosphamide, Doxorubicin, Epcoritamab, Magnetic Resonance Imaging, Polatuzumab Vedotin, Positron Emission Tomography, Prednisone, Rituximab; Procedure · Drug · Biological
Lead sponsor: Jonsson Comprehensive Cancer Center; Other
Eligibility: 70 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: PCD, Primary Ciliary Dyskinesia
Interventions: Exercise, HS pretreatment with Exercise; Behavioral · Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Search by objective public record fields.

Reduction of Depression Through Dual Treatment: Digital CBT & NBHWC Coaching

Oral Fosamprenavir for GERD

Dimensional Changes: Randomized Clinical Trial

Duke Cardiometabolic Prevention Clinic's Impact on High-risk Cardiovascular Patients With Uncontrolled Risk Factors

Investigating Novel Interventions for Low Back Pain in US Military Veterans: A Randomized Controlled Adaptive Phase II Trial

Clinical Evaluation of an Alarm Activated Detection System to Enable Early Intervention of Emerging Respiratory Decline With the Linshom Medical Continuous Predictive Respiratory Sensor (CPRS)

Effects of Risk Presentation Format and Frequently Asked Questions on Breast Cancer Risk Skepticism

Liposomal Bupivacaine vs Perineural Adjuvants in Adductor Canalf and iPACK Blocks in Total Knee Arthroplasty

Supported Online Self-Help for Veterans With Depression in Primary Care

VR-Cognitive Behavioral Therapy Prehabilitation for Spinal Deformity Surgery

Pregnenolone Treatment for Alcohol Use Disorder and Major Depressive Disorder

Intervention for Hearing Health Among Native Americans

PrEP & Soccer: A Program for Pharmacy Chains to Increase PrEP Awareness and Access Among Men

CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock

Feasibility, Acceptability, and Preliminary Effectiveness of Cognitive Behavioral Therapy for Depression in Autistic Youth in Clinical Settings

Antireflux Surgery Without Preoperative Esophageal Manometry

Navigating Hypertension and Food Insecurity

Are Louisiana Pharmacists PrEPared? Implementing Training and an Active PrEP (Pre-Exposure Prophylaxis) Prescribing Surveillance Program

Health Engagement & Access Through Learning, Training, and Health-coaching With People With Intellectual and/or Developmental Disabilities

Pilot Trial of an Emotion Regulation and Executive Functioning Intervention for Self-Injurious Thoughts and Behaviors (SITBs) in Children

Adapting a Psychosocial Support Intervention for the Rett Syndrome Community

Refining Risk Prediction Models for Older Adults Using Electronic Health Records

Epcoritamab and Pola-R-mini-CHP for the Treatment of Diffuse Large B Cell Lymphoma in Elderly or Unfit Patients

Clearance in Primary Ciliary Dyskinesia