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ClinicalTrials.gov public records Last synced Oct 24, 2026, 1:42 AM EDT

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Showing 49–72 of 121 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: PRISM Clear all
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

DARA RVD For High Risk SMM

NCT04775550
View directory record Official record
Conditions
High-risk Smoldering Multiple Myeloma, Multiple Myeloma
Interventions
Daratumumab, Bortezomib, Lenalidomide, Dexamethasone
Drug
Lead sponsor
Omar Nadeem, MD
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2030
U.S. locations
6
States / cities
Stamford, Connecticut • Boston, Massachusetts • Foxborough, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 24, 2026, 1:42 AM EDT
Terminated Not applicable Interventional

Evaluation of Exotropia After Patching the Eye or After Prism Adaptation

NCT05242510
View directory record Official record
Conditions
Exotropia
Interventions
Patching, Prism Adaptation
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
Up to 17 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
5
States / cities
Los Angeles, California • Boston, Massachusetts • Buffalo, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 24, 2026, 1:42 AM EDT
Recruiting Phase 1 Interventional

Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)

NCT07139990
View directory record Official record
Conditions
Small Cell Lung Cancer Extensive Stage, Brain Metastases, Solid Tumor, Adult, Thoracic Cancer, Sarcoma,Soft Tissue, HNPCC
Interventions
Cohort A: Extensive Stage Small Cell Lung Cancer (ES-SCLC) Thoracic Tumor PULSAR (Personalized ultrahypofractionated stereotactic ablative radiotherapy), Cohort B: Brain metastasis PULSAR (Personalized ultrahypofractionated stereotactic ablative radiotherapy), Cohort C: Sarcoma Pre-Operative PULSAR, Cohort D: Resectable Head & Neck Squamous Cell Carcinoma (HNSCC) PULSAR/SAbR
Radiation
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 24, 2026, 1:42 AM EDT
Completed Not applicable Interventional Results available

Case Review of the Penumbra and Indigo Systems for Mechanical Thrombectomy in the Periphery

NCT02085551
View directory record Official record
Conditions
Peripheral Arterial Occlusion or Emboli
Interventions
Mechanical Thrombectomy by the Indigo System
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
Not listed
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
5
States / cities
San Diego, California • Miami, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2020 · Synced Oct 24, 2026, 1:42 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

CATS Tonometer IOP Reduction Latanoprost Verses Timolol

NCT04178863
View directory record Official record
Conditions
Glaucoma; Drugs
Interventions
CATS Tonometer, Latanoprost
Device · Drug
Lead sponsor
Intuor Technologies, Inc.
Industry
Eligibility
18 Years to 101 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 26, 2019 · Synced Oct 24, 2026, 1:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ACTIVATE in Public Housing

NCT06075732
View directory record Official record
Conditions
Pneumonia, Influenza, Varicella Zoster, Meningitis, COVID-19, Vaccine Hesitancy
Interventions
Increasing Willingness and Uptake of Influenza, Pneumonia, Meningitis, HZV, and COVID-19 Vaccination
Behavioral
Lead sponsor
Charles Drew University of Medicine and Science
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Oct 24, 2026, 1:42 AM EDT
Completed Not applicable Interventional Results available

Clinical Trial of Peripheral Prism Glasses for Hemianopia

NCT00494676
View directory record Official record
Conditions
Homonymous Hemianopia
Interventions
High power (57 prism diopter) peripheral prism glasses, Low power sham peripheral prism glasses
Device
Lead sponsor
Alexandra Bowers
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
12
States / cities
Birmingham, Alabama • Palo Alto, California • Jupiter, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 24, 2026, 1:42 AM EDT
Recruiting Not applicable Interventional

Resilience Mobile App for Teens and Young Adults With Cancer

NCT05842902
View directory record Official record
Conditions
Cancer
Interventions
mPRISM
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
12 Years to 25 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 24, 2026, 1:42 AM EDT
Completed Not applicable Interventional

The PRISM Pilot Trial for Post-Traumatic Stress Disorder

NCT04891614
View directory record Official record
Conditions
Post-Traumatic Stress Disorder (PTSD)
Interventions
PRISM
Device
Lead sponsor
GrayMatters Health Ltd.
Industry
Eligibility
22 Years to 65 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2022 · Synced Oct 24, 2026, 1:42 AM EDT
Recruiting Not applicable Interventional

Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

NCT06555939
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Collaborative Care Model, Promoting Resilience in Stress Management
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years to 25 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 24, 2026, 1:42 AM EDT
Completed Not applicable Interventional Results available

The Feasibility of Engage Therapy With Video Support for Homebound Older Adults

NCT05346055
View directory record Official record
Conditions
Depression
Interventions
Engage Prism (2.0)
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Oct 24, 2026, 1:42 AM EDT
Active, not recruiting Not applicable Interventional

PRISM Intervention Study

NCT03883139
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
JASPER, DTT (Discrete Trial Training)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
36 Months to 59 Months
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
3
States / cities
Los Angeles, California • Rochester, New York • Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 24, 2026, 1:42 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

SPIROMICS Study of Early COPD Progression (SOURCE)

NCT05033990
View directory record Official record
Conditions
COPD, Early-Onset
Interventions
Not listed
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
30 Years to 55 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
14
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Los Angeles, California + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 24, 2026, 1:42 AM EDT
Completed Not applicable Interventional Results available

Multiplexing Prism Fitting for Field Expansion of Monocular Vision

NCT06027216
View directory record Official record
Conditions
One Eye Blindness, Blind Left Eye, Blind Right Eye
Interventions
Multiplexing Prism
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
16 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 24, 2026, 1:42 AM EDT
Active, not recruiting No phase listed Observational

PRISM: Patient Experiences With PET Imaging in Prostate Cancer

NCT06523777
View directory record Official record
Conditions
Prostate Cancer
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
7
States / cities
Bridgeport, Connecticut • Derby, Connecticut • Greenwich, Connecticut + 3 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 24, 2026, 1:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Abbott ESA Chagas Assay Post-Market Study

NCT01662362
View directory record Official record
Conditions
Chagas Disease
Interventions
Testing Donor Specimens with ESA Chagas
Device
Lead sponsor
Abbott Diagnostics Division
Industry
Eligibility
17 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
2
States / cities
Rosemont, Illinois • Gaithersburg, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 20, 2014 · Synced Oct 24, 2026, 1:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Mobile Medical Application for Cost-effective Strabismus Screening

NCT03450980
View directory record Official record
Conditions
Strabismus
Interventions
Not listed
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 88 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Oct 24, 2026, 1:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Perceptions Regarding Investigational Screening for Memory Problems in Primary Care

NCT00759252
View directory record Official record
Conditions
Dementia
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older
Enrollment
954 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 28, 2015 · Synced Oct 24, 2026, 1:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Personalized Reminder Information and Social Management System

NCT01497613
View directory record Official record
Conditions
Social Isolation, Social Support (Formal and Informal), Well-being/Quality of Life
Interventions
PRISM C: Computer Condition, PRISM B: Notebook Condition
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
65 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Oct 24, 2026, 1:42 AM EDT
Not listed Not applicable Interventional

PRISM-GENOMICS-Smoking Cessation for Patients With Coronary Artery Disease Undergoing Cardiac Catheterization or Having a Heart Attack at Barnes Hospital in St. Louis Mo

NCT03383224
View directory record Official record
Conditions
Coronary Artery Disease, Smoking Cessation
Interventions
genotype-guided therapy, Nicotine patch, Smoking cessation counseling
Other · Drug · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Oct 24, 2026, 1:42 AM EDT
Recruiting Not applicable Interventional

Comparing Prism Adaptation Training With and Without TENS to Minimize Unilateral Spatial Neglect

NCT07157865
View directory record Official record
Conditions
Unilateral Spatial Neglect, Stroke
Interventions
Prism adaptation training combined with TENS, PAT only
Device · Other
Lead sponsor
Kettering Health Network
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Centerville, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 24, 2026, 1:42 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Evaluation of a Human Immunodeficiency Virus (HIV) Blood Screening Assay

NCT00686205
View directory record Official record
Conditions
Healthy Donors, HIV Positive
Interventions
collection of follow-up sample based on PRISM HIV O Plus result
Device
Lead sponsor
Abbott Diagnostics Division
Industry
Eligibility
17 Years and older
Enrollment
24,111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
7
States / cities
Davenport, Iowa • Kansas City, Missouri • Dayton, Ohio + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 28, 2011 · Synced Oct 24, 2026, 1:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Studying Genes Associated With Non-Hodgkin Lymphoma in Young Patients

NCT01623856
View directory record Official record
Conditions
Childhood Burkitt Lymphoma, Childhood Lymphoblastic Lymphoma
Interventions
laboratory biomarker analysis
Other
Lead sponsor
Children's Oncology Group
Network
Eligibility
Up to 20 Years
Enrollment
483 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Monrovia, California
Source: ClinicalTrials.gov public record
Updated May 7, 2015 · Synced Oct 24, 2026, 1:42 AM EDT
Recruiting Phase 2 Interventional

Immuno-PRISM (PRecision Intervention Smoldering Myeloma)

NCT05469893
View directory record Official record
Conditions
High-risk Smoldering Multiple Myeloma, Smoldering Multiple Myeloma, Multiple Myeloma
Interventions
Teclistamab, Lenalidomide, Dexamethasone
Drug
Lead sponsor
Irene Ghobrial, MD
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
3
States / cities
Denver, Colorado • Boston, Massachusetts • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 24, 2026, 1:42 AM EDT