Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.

Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 11:36 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 56 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: PRK Clear all
Completed Not applicable Interventional

Comparison of Conventional and Custom Photorefractive Keratectomy (PRK)

NCT00713856
View directory record Official record
Conditions
Myopia
Interventions
Custom PRK with iris registration, Conventional PRK
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 19, 2010 · Synced Oct 17, 2026, 11:36 AM EDT
Recruiting No phase listed Observational

Persona Revision Knee System Outcomes

NCT04821154
View directory record Official record
Conditions
Arthroplasty Complications, Infection, Knee Disease, Knee Osteoarthritis
Interventions
Persona Revision Knee System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2033
U.S. locations
16
States / cities
Fayetteville, Arkansas • Little Rock, Arkansas • Fresno, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 17, 2026, 11:36 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A 6 Month Study to Evaluate the Safety, Analgesic Efficacy of ACUVAIL™ (Ketorolac Tromethamine Ophthalmic Solution) 0.45%, in Post-PRK Corneal Wound Healing

NCT01193231
View directory record Official record
Conditions
Must be PRK Candidate
Interventions
Not listed
Lead sponsor
Durrie Vision
Other
Eligibility
18 Years to 39 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 14, 2012 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Post-operative Pain Control After Photorefractive Keratectomy Comparing Acetaminophen/Codeine vs Acetaminophen/Oxycodone

NCT04399122
View directory record Official record
Conditions
Post-operative Pain Control
Interventions
acetaminophen/codeine vs acetaminophen/oxycodone
Drug
Lead sponsor
59th Medical Wing
Federal
Eligibility
21 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Oct 17, 2026, 11:36 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia

NCT02118922
View directory record Official record
Conditions
Keratoconus, Ectasia, Crosslinking, Fuchs' Endothelial Dystrophy
Interventions
Brillouin imaging
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
20 Years to 75 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 17, 2026, 11:36 AM EDT
Completed No phase listed Observational

Patient Reported Outcomes With WaveLight Plus LASIK

NCT07084844
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
WaveLigh Plus LASIK
Device
Lead sponsor
Mann Eye Institute
Other
Eligibility
18 Years to 39 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Not applicable Interventional

Comparison of Photorefractive Keratectomy (PRK) and Sub-Bowman's Keratomileusis (SBK)

NCT00714922
View directory record Official record
Conditions
Myopia
Interventions
PRK, SBK
Procedure
Lead sponsor
University of Utah
Other
Eligibility
21 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 16, 2010 · Synced Oct 17, 2026, 11:36 AM EDT
Terminated No phase listed Observational

Visual Performance of the Vivity IOL in Post-myopic LASIK and PRK Patients

NCT05961046
View directory record Official record
Conditions
Cataract
Interventions
Vivity IOL
Device
Lead sponsor
Laser & Corneal Surgery Associates
Other
Eligibility
40 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
New York, New York • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Post Photorefractive Keratectomy (PRK) Use of an Eye Shield for Maintaining Vision and Mitigating Pain

NCT01592643
View directory record Official record
Conditions
Pain, Vision Nearsighted
Interventions
Eye Shield
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 22, 2021 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Conventional Photorefractive Keratectomy (PRK) in U.S. Army Personnel, Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel

NCT00412568
View directory record Official record
Conditions
Myopia
Interventions
Photorefractive Keratectomy (PRK)
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 1, 2008 · Synced Oct 17, 2026, 11:36 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Anesthetic Impregnated Bandage Soft Contact Lens (BSCL) in Pain Management After Photorefractive Keratectomy (PRK)

NCT04283331
View directory record Official record
Conditions
Myopia, Hypermetropia, Refractive Errors, Astigmatism
Interventions
Proparacaine Ophthalmic
Drug
Lead sponsor
Beeran Meghpara, MD
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 6, 2021 · Synced Oct 17, 2026, 11:36 AM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease Following Photorefractive Keratectomy (PRK)

NCT05045508
View directory record Official record
Conditions
Dry Eye
Interventions
OC-01 (varenicline 0.6mg/ml) nasal spray, Placebo (vehicle) Nasal Spray
Drug
Lead sponsor
Brandon Baartman
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparison of Fellow Eyes Undergoing LASIK or PRK With a Wavefront-guided Excimer Laser Versus a Wavefront-optimized Excimer Laser

NCT01135719
View directory record Official record
Conditions
Hyperopia, Myopia, Astigmatism
Interventions
LASIK and PRK
Procedure
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years to 60 Years
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Phase 2 Interventional Results available

Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP)

NCT04630158
View directory record Official record
Conditions
Chronic Ocular Pain
Interventions
SAF312 Placebo, SAF312
Other · Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
24
States / cities
Mission Hills, California • Newport Beach, California • Palo Alto, California + 19 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Oral Gabapentin Versus Placebo for Treatment of Postoperative Pain Following Photorefractive Keratectomy

NCT00793910
View directory record Official record
Conditions
Postoperative Pain
Interventions
Gabapentin, placebo
Drug
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 16, 2014 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of the Effect of 4th Generation Fluoroquinolones, Gatifloxacin and Moxifloxacin, on Epithelial Healing Following Photorefractive Keratectomy (PRK), A Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel (WU # 2335-99)

NCT00414011
View directory record Official record
Conditions
Epithelium, Corneal
Interventions
Moxifloxacin, Gatifloxacin
Drug
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Ends 2005
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 17, 2013 · Synced Oct 17, 2026, 11:36 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy

NCT00954187
View directory record Official record
Conditions
Postoperative Pain
Interventions
Gabapentin, pregabalin
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2017 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Initial Evaluation of Photorefractive Keratectomy in U.S. Army Personnel

NCT00413673
View directory record Official record
Conditions
Myopia
Interventions
PRK
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 1, 2008 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Cannabinoid vs Opioid for Photorefractive Keratectomy Pain Control

NCT05477875
View directory record Official record
Conditions
Photorefractive Keratectomy, Myopia, Hyperopia
Interventions
oral cannabinoid, oral codeine/acetaminophen
Drug · Combination Product
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 17, 2026, 11:36 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

An Evaluation of LASIK, SMILE and PRK Surgery in Physicians

NCT02576483
View directory record Official record
Conditions
Nearsightedness, Farsightedness, Astigmatism
Interventions
Questionnaire (QoV questionnaire)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 62 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Phase 4 Interventional

A Comparison of Topical Nepafenac to Placebo in Corneal Epithelial Healing Times and Postoperative Pain Relief

NCT00330798
View directory record Official record
Conditions
Photorefractive Keratectomy
Interventions
nepafenac 0.1%, ketorolac 0.4%
Drug · Other
Lead sponsor
Alcon Research
Industry
Eligibility
19 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2016 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Processed Amniotic Fluid (PAF) Drops After Photorefractive Keratectomy (PRK)

NCT04281004
View directory record Official record
Conditions
Photorefractive Keratectomy
Interventions
Amniotic Fluid (AFED), Saline Solution
Biological · Other
Lead sponsor
University of Utah
Other
Eligibility
21 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 17, 2026, 11:36 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

A Comparison of Photorefractive Keratectomy (PRK), PRK With Mitomycin-C and Laser Subepithelial Keratomileusis (LASEK) in the Treatment of Moderate and High Myopia

NCT00415077
View directory record Official record
Conditions
MODERATE AND HIGH MYOPIA
Interventions
PRK, MMC PRK, LASEK
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
960 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2004
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 16, 2010 · Synced Oct 17, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Goblet Cell Response and Dry Eye Symptoms After PRK and LASIK

NCT00411827
View directory record Official record
Conditions
Keratoconjunctivitis Sicca
Interventions
PRK with conjunctival impression cytology before and after surgery, LASIK with conjunctival impression cytology before and after surgery
Procedure
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
21 Years to 40 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 20, 2024 · Synced Oct 17, 2026, 11:36 AM EDT