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ClinicalTrials.gov public records Last synced Oct 23, 2026, 5:50 AM EDT

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Showing 145–168 of 171 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: PRP Injection Clear all
Withdrawn Phase 2 Interventional

How Does Platelet Dose Impact Clinical Outcomes After PRP Treatment?

NCT05330689
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
PRP injection dose (<5 billion platelets), PRP injection dose (between 5 and <10 billion platelets), PRP injection dose (between 10 and <20 billion platelets), PRP injection dose (20 billion or greater platelets), Saline injection control
Biological · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
40 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 26, 2024 · Synced Oct 23, 2026, 5:50 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Ovarian Function Following Intraovarian Injection of PRP

NCT04278313
View directory record Official record
Conditions
Diminished Ovarian Reserve, Diminished Ovarian Reserve Due to Advanced Maternal Age
Interventions
PRP - Platelet Rich Plasma, PPP - Platelet Poor Plasma
Procedure
Lead sponsor
Center for Human Reproduction
Other
Eligibility
21 Years to 44 Years · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 23, 2026, 5:50 AM EDT
Active, not recruiting Phase 4 Interventional

High Dose Eylea for Proliferative Diabetic Retinopathy Outcomes

NCT07118670
View directory record Official record
Conditions
Proliferative Diabetic Retinopathy (PDR)
Interventions
Aflibercept 8mg
Drug
Lead sponsor
Edward Wood, MD
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
Austin, Texas • Bellaire, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 23, 2026, 5:50 AM EDT
Completed Not applicable Interventional

Validation of a Low-cost Platelet-Rich Plasma (PRP)

NCT06184048
View directory record Official record
Conditions
Platelet-Rich Plasma (PRP), Knee Osteoarthritis (OA)
Interventions
Intra-Articular knee injection of LC-PRP
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Oct 23, 2026, 5:50 AM EDT
Completed Not applicable Interventional

Serial Platelet-Rich Plasma Injections for Vocal Fold Atrophy, Scar, and/or Sulcus Vocalis

NCT03749863
View directory record Official record
Conditions
Presbylarynx, Atrophy; Larynx, Dysphonia, Vocal Cord Atrophy, Presbylarynges, Vocal Fold Scar, Sulcus Vocalis of Vocal Cord
Interventions
Serial PRP injections
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 23, 2026, 5:50 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Autologous Alpha-2 Macroglobulin Rich Plasma, Safety and Efficacy in Symptomatic Moderate Knee Osteoarthritis

NCT06329492
View directory record Official record
Conditions
Osteoarthritis, OA, Knee Osteoarthritis
Interventions
Autologous Alpha-2 Macroglobulin Rich Plasma (A2MRP)
Biological
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 23, 2026, 5:50 AM EDT
Completed Not applicable Interventional

Platelet Rich Plasma (PRP) for Facet Mediated Lumbar Low Back Pain

NCT04822753
View directory record Official record
Conditions
Facet Joint Pain; Low Back Pain
Interventions
Platelet Rich Plasma injection to the lumbar facet joint
Procedure
Lead sponsor
Womack Army Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Fort Liberty, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 23, 2026, 5:50 AM EDT
Terminated Not applicable Interventional

Registry Trial of the Effectiveness of Platelet Rich Plasma for Chronic Non-Healing Wounds

NCT02071979
View directory record Official record
Conditions
Diabetic Foot Ulcers, Venous Ulcers, Pressure Ulcers
Interventions
Autologous PRP Gel, Autologous PRP Injections, Autologous PRP Gel plus PRP Injections, Standard Wound Care
Device · Procedure
Lead sponsor
Arteriocyte, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
6
States / cities
Bakersfield, California • Idaho Falls, Idaho • Englewood, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Oct 23, 2026, 5:50 AM EDT
Terminated Phase 2 Interventional Results available

Intravitreal Ranibizumab to Treat Macular Edema After Panretinal Photocoagulation (Phase II)

NCT00668785
View directory record Official record
Conditions
Proliferative Diabetic Retinopathy, Macular Edema
Interventions
ranibizumab
Drug
Lead sponsor
Jumper, J. Michael, M.D.
Individual
Eligibility
21 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2019 · Synced Oct 23, 2026, 5:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Use of PRP and BMC in Patients With Internal Disc Disruption Multicenter Prospective Randomized Controlled Trial in Patients With Internal Disc Disruption

NCT04102761
View directory record Official record
Conditions
Internal Disc Disruption
Interventions
Intradiscal PRP & BMC Injections
Procedure
Lead sponsor
Annu Navani
Other
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
4
States / cities
Campbell, California • Los Angeles, California • Tyler, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Oct 23, 2026, 5:50 AM EDT
Not listed No phase listed Observational

Biologically Assisted Core Decompression of the Femoral Head Using the PerFuse Instrument and BioCUE

NCT02662881
View directory record Official record
Conditions
Avascular Necrosis of the Femoral Head
Interventions
PerFuse Percutaneous Decompression System, BioCUE Platelet Concentration System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
4
States / cities
St Louis, Missouri • Cleveland, Ohio • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2021 · Synced Oct 23, 2026, 5:50 AM EDT
Completed Phase 1 Interventional

Platelet Rich Plasma for the Treatment of Genitourinary Syndrome of Menopause in Patients With Stage 0-III Breast Cancer

NCT04535323
View directory record Official record
Conditions
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Breast Adenocarcinoma, Genitourinary Syndrome of Menopause, Prognostic Stage 0 Breast Cancer AJCC v8, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions
Quality-of-Life Assessment, Questionnaire Administration, Therapeutic Autologous Platelet-rich Plasma
Other · Biological
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced Oct 23, 2026, 5:50 AM EDT
Recruiting Phase 2 Interventional

Intra-articular Platelet-Rich Plasma Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis

NCT03491761
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
PRP Treatment, HA Treatment
Biological
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Skokie, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 23, 2026, 5:50 AM EDT
Active, not recruiting Phase 2 Interventional

A Novel Therapy for Breast Cancer Survivors With Genitourinary Syndrome of Menopause

NCT05812924
View directory record Official record
Conditions
Breast Cancer, Genitourinary Syndrome of Menopause
Interventions
Platelet-rich plasma (PRP)
Biological
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 23, 2026, 5:50 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Combining Shockwave Therapy and Platelet Rich Plasma to Treat Erectile Dysfunction in Diabetic Men (COCKTAIL-DM)

NCT05525572
View directory record Official record
Conditions
Erectile Dysfunction With Diabetes Mellitus
Interventions
Shockwave Therapy (SWT), Autologous Platelet-Rich Plasma (PRP)
Device · Drug
Lead sponsor
University of Miami
Other
Eligibility
30 Years to 80 Years · Male only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 28, 2025 · Synced Oct 23, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ovarian PRP for Diminished Ovarian Reserve

NCT05790655
View directory record Official record
Conditions
Diminished Ovarian Reserve
Interventions
oPRP, Placebo- Serum
Other
Lead sponsor
Generation Next Fertility
Other
Eligibility
35 Years to 42 Years · Female only
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Oct 23, 2026, 5:50 AM EDT
Completed Phase 1Phase 2 Interventional

Activated PRP for Treatment of Androgenetic Alopecia

NCT05348343
View directory record Official record
Conditions
Androgenetic Alopecia
Interventions
Autologous platelet-rich plasma
Biological
Lead sponsor
Santiste Medical Inc.
Industry
Eligibility
30 Years to 60 Years · Male only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 23, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional

Bone Marrow Aspirate Concentrate (BMAC)Treatment for Knee Osteoarthritis

NCT04716803
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Bone Marrow Aspirate Concentrate, Angel Concentrated Platelet Rich Plasma (cPRP) System
Biological · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
45 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Oct 23, 2026, 5:50 AM EDT
Completed Phase 2 Interventional Results available

Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears

NCT04088227
View directory record Official record
Conditions
Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture
Interventions
Experimental Group, Control Group
Drug · Other
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
14 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Oct 23, 2026, 5:50 AM EDT
Completed Phase 2 Interventional Results available

A Prospective Comparison of Ultrasound-Guided Percutaneous Platelet-Rich Plasma Injection

NCT01600326
View directory record Official record
Conditions
Tendinosis, Tendinitis
Interventions
Tenotomy (no injection), Ultrasound guided platelet rich plasma injection
Procedure · Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 23, 2026, 5:50 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Efficacy & Safety Trial of Intravitreal Injections Combined With PRP for CSME Secondary to Diabetes Mellitus (DAVE)

NCT01552408
View directory record Official record
Conditions
Diabetic Macular Edema
Interventions
0.3 mg ranibizumab, Targeted Pan Retinal Photocoagulation
Drug · Procedure
Lead sponsor
David M. Brown, M.D.
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
3
States / cities
Houston, Texas • Katy, Texas • The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2018 · Synced Oct 23, 2026, 5:50 AM EDT
Completed Phase 3 Interventional

Comparing Platelet Rich Plasma and Corticosteroid for Military & Civilian Patients With Glenohumeral Osteoarthritis

NCT05160441
View directory record Official record
Conditions
Osteoarthritis of the Shoulder, Corticosteroid, PRP, Pain
Interventions
Platelet Rich Plasma Injection, Corticosteroid Injection, Delayed Platelet Rich Plasma Injection After Corticosteroid Injection Failure
Biological
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Oct 23, 2026, 5:50 AM EDT
Completed No phase listed Observational Results available

Performance-Enhancing Effects of Platelet-Rich Plasma (PRP) Injections

NCT01200875
View directory record Official record
Conditions
Tendinopathy, Rheumatic Diseases
Interventions
Ultrasound-guided platelet-rich-plasma (PRP) injection, Platelet-Rich Plasma (PRP)
Procedure
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2018 · Synced Oct 23, 2026, 5:50 AM EDT
Completed Phase 4 Interventional Results available

Bone Marrow Aspirate Compared to Platelet Rich Plasma for Treating Knee Osteoarthritis

NCT03289416
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Pure PRP II, PureBMC
Combination Product
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Apr 20, 2025 · Synced Oct 23, 2026, 5:50 AM EDT