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Showing 1–24 of 234 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Pacemaker Clear all
Completed Phase 1 Interventional

Natural History and Results of Dual Chamber (DDD) Pacemaker Therapy of Children With Obstructive Hypertrophic Cardiomyop...

NCT00001396
View directory record Official record
Conditions
Hypertrophic Cardiomyopathy
Interventions
Paragon Pacemaker
Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
5 Years to 20 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 8, 2026, 10:19 PM EDT
Completed No phase listed Observational

Study Evaluating the Use of MRI on CMS Patients

NCT02513056
View directory record Official record
Conditions
Pacemaker, Implantable Cardioverter Defibrillators
Interventions
MRI
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
872 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Sep 8, 2026, 10:19 PM EDT
Active, not recruiting Not applicable Interventional

Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction

NCT05839730
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction, Concentric Hypertrophy
Interventions
Pacemaker PLR + TRT ON, Pacemaker non-pacing mode or an exertional rate-adaptive pacing mode with no planned pacing at rest.
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
8
States / cities
Naples, Florida • O'Fallon, Illinois • Springfield, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 8, 2026, 10:19 PM EDT
Not listed No phase listed Observational

Amyloidosis Incidence in High-Risk Cardiac Device Patients

NCT06186167
View directory record Official record
Conditions
Amyloid, Cardiac Amyloidosis, Amyloidosis Cardiac, Systemic Amyloidosis, AL Amyloidosis, Infiltrative Cardiomyopathy, Amyloid, ATTR Amyloidosis Wild Type
Interventions
Chest Wall Fat Tissue Collection
Procedure
Lead sponsor
Midwest Heart & Vascular Specialists
Other
Eligibility
40 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Sep 8, 2026, 10:19 PM EDT
Completed No phase listed Observational Results available

Patient Preferences for Leadless Pacemakers

NCT05327101
View directory record Official record
Conditions
Cardiac Rhythm Disorder, Bradycardia, Cardiac Pacemaker Artificial
Interventions
Patient Preference Survey
Other
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
117 participants
Timeline
2022 – 2023
U.S. locations
11
States / cities
Scottsdale, Arizona • Jonesboro, Arkansas • Little Rock, Arkansas + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Sep 8, 2026, 10:19 PM EDT
Completed No phase listed Observational

Enhancing Knowledge Implantable Cardioverter-Defibrillators (ICDs)

NCT00822965
View directory record Official record
Conditions
Pacemaker, Implantable Cardioverter-Defibrillators
Interventions
Questionnaires, Phone Interviews, Educational Packet
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 6, 2016 · Synced Sep 8, 2026, 10:19 PM EDT
Terminated No phase listed Observational

His Bundle Recording From Subclavian Vein

NCT04115735
View directory record Official record
Conditions
Atrial Fibrillation, Congestive Heart Failure
Interventions
Not listed
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years to 105 Years
Enrollment
1 participant
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Sep 8, 2026, 10:19 PM EDT
Active, not recruiting No phase listed Observational

Micra Transcatheter Pacing System Post-Approval Registry

NCT02536118
View directory record Official record
Conditions
Bradycardia
Interventions
Micra Transcatheter Pacing System
Device
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
3,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
52
States / cities
Birmingham, Alabama • Los Angeles, California • Redwood City, California + 49 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 8, 2026, 10:19 PM EDT
Completed No phase listed Observational Results available

Imaging Study of Lead Implant for His Bundle Pacing

NCT03294317
View directory record Official record
Conditions
Cardiac Pacemaker, Artificial
Interventions
His bundle pacing
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Indianapolis, Indiana • Wilkes-Barre, Pennsylvania • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 31, 2021 · Synced Sep 8, 2026, 10:19 PM EDT
Active, not recruiting No phase listed Observational

Factors Associated With Response to Cardiac Resynchronization Therapy in Heart Failure Patients With Non-LBBB ECG Pattern

NCT06977217
View directory record Official record
Conditions
Cardiomyopathies, Heart Failure, Non-left Bundle Branch Block, Cardiac Resynchronization Therapy
Interventions
CRT-D implantation
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 8, 2026, 10:19 PM EDT
Terminated Not applicable Interventional Results available

APPROPRIATE - Rate Adaptive Pacing Sensor

NCT00757666
View directory record Official record
Conditions
Heart Diseases
Interventions
Rate adaptive pacemaker
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
566 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Jonesboro, Arkansas • Davenport, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 8, 2026, 10:19 PM EDT
Terminated Not applicable Interventional

Superficial Cervical Plexus Block for Pacemaker Insertion

NCT01473667
View directory record Official record
Conditions
Pacemaker Insertion, Regional Block, Pain
Interventions
Superficial Cervical Plexus Block (SCP) block, Local site infiltration
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Sep 8, 2026, 10:19 PM EDT
Completed Not applicable Interventional Results available

Metabolic Mapping and Cardiac Resynchronization

NCT03420833
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac resynchronization therapy pacemaker (CRT-P)
Device
Lead sponsor
Yong-Mei Cha
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Sep 8, 2026, 10:19 PM EDT
Not listed No phase listed Observational

A Retrospective Trial to Evaluate the Micra Pacemaker

NCT04051814
View directory record Official record
Conditions
Pacemaker
Interventions
Micra Transcatheter Pacemaker System
Other
Lead sponsor
Hoag Memorial Hospital Presbyterian
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Newport Beach, California
Source: ClinicalTrials.gov public record
Updated Feb 27, 2023 · Synced Sep 8, 2026, 10:19 PM EDT
Recruiting Not applicable Interventional

Chronic Evaluation of Novel Pacemaker System

NCT06056817
View directory record Official record
Conditions
Ventricular Pacing With Rate Response, Bradycardia
Interventions
Calyan Pacemaker
Device
Lead sponsor
Calyan Technologies
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 8, 2026, 10:19 PM EDT
Not yet recruiting Not applicable Interventional

Early Feasibility Study of 3830 Lead Implantation Via the Middle Cardiac Vein in Patients With Prior or Planned Tricuspid Valve Intervention

NCT07805525
View directory record Official record
Conditions
Cardiac Conduction Disorders Requiring Permanent Pacing in Patients With Prior or Planned Tricuspid Valve Intervention
Interventions
Pacemaker
Device
Lead sponsor
Minneapolis Heart Institute Foundation
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 8, 2026, 10:19 PM EDT
Completed No phase listed Observational Results available

Physiologic Pacing Registry

NCT03719040
View directory record Official record
Conditions
Bradycardia, Sinus Node Dysfunction, Heart Block, Syncope, Cardiomyopathies, Ventricular Tachycardia, Heart Failure
Interventions
Physiologic pacing device implant
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
870 participants
Timeline
2018 – 2021
U.S. locations
26
States / cities
Huntsville, Alabama • Burlingame, California • San Diego, California + 22 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 8, 2026, 10:19 PM EDT
Completed Phase 2 Interventional Results available

Study to Evaluate the Effect of Ranolazine and Dronedarone When Given Alone and in Combination in Patients With Paroxysmal Atrial Fibrillation

NCT01522651
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Ranolazine, Dronedarone, Ranolazine placebo, Dronedarone placebo
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
15
States / cities
Beverly Hills, California • Newport Beach, California • San Francisco, California + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Sep 8, 2026, 10:19 PM EDT
Completed No phase listed Observational

Long-Term Results of DDD Pacing in Obstructive Hypertrophic Cardiomyopathy

NCT00001530
View directory record Official record
Conditions
Cardiomyopathy, Hypertrophic
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 8, 2026, 10:19 PM EDT
Terminated No phase listed Observational

Cardiac Output in Heart Failure Patients With Mechanical Pumps

NCT05195931
View directory record Official record
Conditions
Heart Failure, Systolic, Mechanical Circulatory Support, Cardiovascular Hemodynamics
Interventions
preload challenge, afterload challenge, contractility assessment
Diagnostic Test
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Sep 8, 2026, 10:19 PM EDT
Completed Not applicable Interventional Results available

Multi-Channel Gastric Electrical Stimulation for the Treatment of Gastroparesis

NCT00595621
View directory record Official record
Conditions
Gastric Stasis
Interventions
Enterra Multi-Channel Phased Gastric Pacemaker (MGP-1)
Device
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Sep 8, 2026, 10:19 PM EDT
Completed Not applicable Interventional Results available

ImageReady(TM) MR Conditional Pacing System Clinical Study

NCT01781078
View directory record Official record
Conditions
Bradycardia, Sinus Node Dysfunction
Interventions
MRI, ImageReady System implant
Radiation · Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
363 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
29
States / cities
Mesa, Arizona • Los Angeles, California • San Francisco, California + 26 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2019 · Synced Sep 8, 2026, 10:19 PM EDT
Recruiting Not applicable Interventional

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

NCT06059638
View directory record Official record
Conditions
Hypertension, Hypertension, Systolic, Hypertension, Essential
Interventions
Medtronic Astra/Azure DR MRI IPG with AVIM therapy Activated, Medtronic Astra/Azure DR MRI IPG with AVIM therapy Deactivated
Device
Lead sponsor
Orchestra BioMed, Inc
Industry
Eligibility
18 Years and older
Enrollment
316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
72
States / cities
Scottsdale, Arizona • Glendale, California • Newport Beach, California + 60 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 8, 2026, 10:19 PM EDT
Terminated No phase listed Observational

Study of the Loss of AV Synchrony at Maximum Exercise

NCT03859167
View directory record Official record
Conditions
Exercise, Pacemaker, Blood Pressure
Interventions
Stress Test
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
9 participants
Timeline
2019 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Sep 8, 2026, 10:19 PM EDT