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ClinicalTrials.gov public records Last synced Oct 25, 2026, 9:49 AM EDT

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Showing 1–24 of 235 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pacemaker Clear all
Active, not recruiting No phase listed Observational

Aveir VR Real-World Evidence Post-Approval Study

NCT05270499
View directory record Official record
Conditions
Cardiac Pacemaker, Arrythmia, Bradycardia
Interventions
Aveir VR Leadless Pacemaker System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
3,427 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2034
U.S. locations
1
States / cities
Sylmar, California
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 25, 2026, 9:49 AM EDT
Completed No phase listed Observational Results available

ProMRI Study of the Entovis Pacemaker System (Phase B)

NCT02009696
View directory record Official record
Conditions
Magnetic Resonance Imaging (MRI); Cardiac Pacing
Interventions
Patients with a ProMRI Pacemaker System, Magnetic Resonance Imaging (MRI) scan
Device · Other
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
32
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Concord, California + 28 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2015 · Synced Oct 25, 2026, 9:49 AM EDT
Completed Not applicable Interventional

Effectiveness of Closed Loop Stimulation (CLS) With His Bundle Lead Placement

NCT03601754
View directory record Official record
Conditions
Sinus Node Dysfunction
Interventions
Treadmill/Bicycle exercise testing
Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Oct 25, 2026, 9:49 AM EDT
Completed Not applicable Interventional Results available

HIS-Purkinje Conduction System Pacing Optimized Trial of Cardiac Resynchronization Therapy

NCT04561778
View directory record Official record
Conditions
Heart Failure，Congestive, Cardiomyopathies, Left Ventricular Dysfunction
Interventions
HOT-CRT, Biventricular Pacing
Device
Lead sponsor
Pugazhendhi Vijayaraman
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 25, 2026, 9:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study to Evaluate a Prototype Electronic Uterine Inhibitor to Prevent Preterm Contractions

NCT00212446
View directory record Official record
Conditions
Preterm Birth
Interventions
Electrical Intervention (EI)
Device
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 17, 2018 · Synced Oct 25, 2026, 9:49 AM EDT
Enrolling by invitation Not applicable Interventional

Percutaneous Closure Versus Figure-of-eight Suture for Hemostasis in Leadless Pacemaker Implantation.

NCT06837870
View directory record Official record
Conditions
Vascular Closure, Pacemaker Implantation, Leadless Pacemaker
Interventions
percutaneous suture mediated closure, Figure of Eight Suture
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 25, 2026, 9:49 AM EDT
Completed No phase listed Observational

HBP Device EGM Data Collection

NCT03564860
View directory record Official record
Conditions
Sick Sinus Syndrome, AV Block, Heart Failure
Interventions
Device data collection
Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Huntsville, Alabama • Sayre, Pennsylvania • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 25, 2026, 9:49 AM EDT
Completed Not applicable Interventional

Novel Cardiac Pacing to Initiate Cardiac Remodeling in Heart Failure

NCT05600725
View directory record Official record
Conditions
Cardiomyopathies, Heart Rate, Conditioning
Interventions
novel atrial pacing approach, sham pacing approach
Other
Lead sponsor
Denise Hodgson-Zingman
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Oct 25, 2026, 9:49 AM EDT
Completed No phase listed Observational

A Comparison of Rate Response Performance in Pacemaker Patients With an Indication of Sinus Node Dysfunction

NCT02027909
View directory record Official record
Conditions
Sinus Node Dysfunction
Interventions
Reprogramming dual chamber pacemaker
Device
Lead sponsor
Arun Rao
Other
Eligibility
60 Years to 95 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Kingsport, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Oct 25, 2026, 9:49 AM EDT
Withdrawn Not applicable Interventional

RESPECT Heart Failure- RESpiratory Pattern Evaluation in Clinical Trials for HF

NCT04757246
View directory record Official record
Conditions
Heart Failure
Interventions
MouthLab Device
Other
Lead sponsor
WakeMed Health and Hospitals
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2022 · Synced Oct 25, 2026, 9:49 AM EDT
Completed Not applicable Interventional Results available

Intra-procedural Transthoracic EChocardiogram to Facilitate Left Bundle Branch Area Pacing (LBBAP)

NCT05646251
View directory record Official record
Conditions
Heart Failure
Interventions
Heart Ultrasound
Device
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 25, 2026, 9:49 AM EDT
Active, not recruiting No phase listed Observational

AVEIR DR Coverage With Evidence Development (CED) Study

NCT05932602
View directory record Official record
Conditions
Cardiac Pacemaker, Arrythmia, Bradycardia
Interventions
Aveir DR Leadless Pacemaker System, Dual Chamber Transvenous Pacemaker
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
2,812 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Sylmar, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 25, 2026, 9:49 AM EDT
Terminated No phase listed Observational

Cardiac Output in Heart Failure Patients With Mechanical Pumps

NCT05195931
View directory record Official record
Conditions
Heart Failure, Systolic, Mechanical Circulatory Support, Cardiovascular Hemodynamics
Interventions
preload challenge, afterload challenge, contractility assessment
Diagnostic Test
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 25, 2026, 9:49 AM EDT
Recruiting No phase listed Observational

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

NCT00271180
View directory record Official record
Conditions
Arrhythmia, Bradycardia, Heart Failure, Sinus Tachycardia
Interventions
Device
Device
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1983 – 2040
U.S. locations
113
States / cities
Birmingham, Alabama • Anchorage, Alaska • Chandler, Arizona + 110 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 25, 2026, 9:49 AM EDT
Terminated No phase listed Observational

SJM Brady MRI Post Approval Study

NCT03170583
View directory record Official record
Conditions
Bradycardia
Interventions
St. Jude Medical Tendril MRI™ lead
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,768 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
66
States / cities
Phoenix, Arizona • Jonesboro, Arkansas • Little Rock, Arkansas + 62 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 25, 2026, 9:49 AM EDT
Completed Phase 4 Interventional

MAKE IT CLEAN, Impact of Pocket Revision on the Rate of Infection and Other Complications in Patients Requiring Pocket Manipulation for Generator Replacement and/or Lead Replacement or Revision: A Prospective Randomized Study

NCT00599261
View directory record Official record
Conditions
Infection
Interventions
ICD/pacemaker pocket revision
Procedure
Lead sponsor
Dhanunjaya Lakkireddy, MD, FACC
Other
Eligibility
18 Years and older
Enrollment
265 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 10, 2013 · Synced Oct 25, 2026, 9:49 AM EDT
Completed Not applicable Interventional Results available

Effect of Chronic Changes in Heart Rate on Congestive Heart Failure

NCT00389649
View directory record Official record
Conditions
Heart Failure, Congestive
Interventions
heart rate setting
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 20, 2021 · Synced Oct 25, 2026, 9:49 AM EDT
Terminated No phase listed Observational Results available

Arrythmia Burden in Cardiac Contractility Modulation (CCM)

NCT05704426
View directory record Official record
Conditions
Atrial Fibrillation, Arrythmia
Interventions
Impulse Dynamics Optimizer Device
Device
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Oct 25, 2026, 9:49 AM EDT
Completed Phase 2Phase 3 Interventional

Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure

NCT00180258
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Cardiac Resynchronization Therapy with & without defibrillator
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 25, 2007 · Synced Oct 25, 2026, 9:49 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Exploring the Modulatory Role of Sex Hormones Along the Neuromechanical Axis in Females

NCT03947684
View directory record Official record
Conditions
Role of Sex Hormones Along the Neuromechanical Axis
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 39 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 25, 2026, 9:49 AM EDT
Completed Not applicable Interventional Results available

ECG Belt to Assess Electrical Synchronization

NCT04583709
View directory record Official record
Conditions
Bradycardia, Heart Failure
Interventions
ECG Belt
Device
Lead sponsor
Pugazhendhi Vijayaraman
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 25, 2026, 9:49 AM EDT
Completed No phase listed Observational Results available

REPLACE: Implantable Cardiac Pulse Generator Replacement Registry

NCT00395447
View directory record Official record
Conditions
Device Replacement, Elective Replacement (ERI), Device Advisory, Device Upgrade, Postoperative Complications
Interventions
Straight-forward Device Replacement, Device Replacement with Upgrade
Procedure
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,744 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
71
States / cities
Birmingham, Alabama • Mesa, Arizona • Modesto, California + 58 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 25, 2026, 9:49 AM EDT
Active, not recruiting No phase listed Observational

Longitudinal Coverage With Evidence Development Study on Micra AV Leadless Pacemakers (Micra AV CED)

NCT04235491
View directory record Official record
Conditions
Bradycardia
Interventions
Not listed
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
37,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 25, 2026, 9:49 AM EDT
Completed Not applicable Interventional Results available

Reducing Episodes by Septal Pacing Efficacy Confirmation Trial (RESPECT)

NCT00289289
View directory record Official record
Conditions
Atrial Fibrillation, Tachycardia, Supraventricular, Arrhythmia, Bradycardia
Interventions
Intervention Pacing Features
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
34
States / cities
Little Rock, Arkansas • Rancho Mirage, California • San Diego, California + 31 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2012 · Synced Oct 25, 2026, 9:49 AM EDT