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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Pacing Lead Clear all
Terminated Not applicable Interventional Results available

Optimize RV Selective Site Pacing Clinical Trial

NCT00422669
View directory record Official record
Conditions
Cardiac Pacing, Artificial, Cardiac Pacemaker, Artificial
Interventions
Medtronic Dual-Chamber Pacemaker, Medtronic SelectSecure 3830 Lead
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
16
States / cities
Bridgeport, Connecticut • Clearwater, Florida • Hudson, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2013 · Synced Sep 15, 2026, 8:03 AM EDT
Completed No phase listed Observational

Diaphragm Pacing After Spinal Cord Injury

NCT02556125
View directory record Official record
Conditions
Injuries, Spinal Cord
Interventions
Diaphragm pacing
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Sep 15, 2026, 8:03 AM EDT
Completed Phase 4 Interventional

Predictive Risk Stratification Through T Variability in ICD Patients Without Pacing Indications

NCT00560768
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Ovatio VR 6250 or DR6550
Device
Lead sponsor
LivaNova
Industry
Eligibility
Not listed
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
7
States / cities
Sheffield, Alabama • Tarzana, California • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2015 · Synced Sep 15, 2026, 8:03 AM EDT
Completed No phase listed Observational Results available

Physiologic Pacing Registry

NCT03719040
View directory record Official record
Conditions
Bradycardia, Sinus Node Dysfunction, Heart Block, Syncope, Cardiomyopathies, Ventricular Tachycardia, Heart Failure
Interventions
Physiologic pacing device implant
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
870 participants
Timeline
2018 – 2021
U.S. locations
26
States / cities
Huntsville, Alabama • Burlingame, California • San Diego, California + 22 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 15, 2026, 8:03 AM EDT
Active, not recruiting No phase listed Observational

Characterizing Outcomes and Real-World Experience of Cardiac Physiologic Pacing (The CORE-CPP Study)

NCT06606288
View directory record Official record
Conditions
Heart Failure
Interventions
Conduction system pacing, Bi-ventricular pacing
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
Not listed
Enrollment
6,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2030
U.S. locations
1
States / cities
Mounds View, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 15, 2026, 8:03 AM EDT
Completed Not applicable Interventional Results available

The EASYTRAK EPI Clinical Investigation

NCT00158925
View directory record Official record
Conditions
Bradycardia, Congestive Heart Failure
Interventions
EASYTRAK EPI lead
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Sep 15, 2026, 8:03 AM EDT
Completed No phase listed Observational

HBP Device EGM Data Collection

NCT03564860
View directory record Official record
Conditions
Sick Sinus Syndrome, AV Block, Heart Failure
Interventions
Device data collection
Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Huntsville, Alabama • Sayre, Pennsylvania • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 15, 2026, 8:03 AM EDT
Not yet recruiting Not applicable Interventional

Early Feasibility Study of 3830 Lead Implantation Via the Middle Cardiac Vein in Patients With Prior or Planned Tricuspid Valve Intervention

NCT07805525
View directory record Official record
Conditions
Cardiac Conduction Disorders Requiring Permanent Pacing in Patients With Prior or Planned Tricuspid Valve Intervention
Interventions
Pacemaker
Device
Lead sponsor
Minneapolis Heart Institute Foundation
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 15, 2026, 8:03 AM EDT
Completed Phase 2 Interventional Results available

Post-Myocardial Infarction Remodeling Prevention Therapy

NCT01213251
View directory record Official record
Conditions
Acute Myocardial Infarction, Pacing Therapy, Cardiac Remodeling, Heart Failure
Interventions
Single Site Pacing, Dual Site Pacing
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
17
States / cities
Scottsdale, Arizona • Los Angeles, California • Atlanta, Georgia + 14 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2016 · Synced Sep 15, 2026, 8:03 AM EDT
Completed Not applicable Interventional

Functional Outcomes in CondUction System Pacing and Right Ventricular Synchrony (FOCUS-Right)

NCT06601322
View directory record Official record
Conditions
Left Branch Bundle Block, RV - Right Ventricular Abnormality
Interventions
Pacemaker Interrogation and Electrocardiogram (ECG):, Cardiopulmonary Exercise Test (CPET) and Exercise Stress Cardiac Magnetic Resonance (ExeCMR, Continuous pacemaker telemetry (CPT)
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 15, 2026, 8:03 AM EDT
Active, not recruiting Not applicable Interventional

REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT)

NCT05652218
View directory record Official record
Conditions
Left Ventricular Ejection Fraction, Heart Failure (HF), Left Bundle-Branch Block
Interventions
LB-CRT, BIV-CRT
Device
Lead sponsor
Inova Health Care Services
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Durham, North Carolina • Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 15, 2026, 8:03 AM EDT
Not listed Not applicable Interventional

Multi-lead ECG to Effectively Optimize Resynchronization Devices: New CRT Recipients

NCT04083690
View directory record Official record
Conditions
Heart Failure, Systolic
Interventions
Reprogramming of CRT Device Settings to Optimal Electrical Synchrony
Device
Lead sponsor
Allina Health System
Other
Eligibility
18 Years to 100 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Minneapolis, Minnesota • Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Sep 15, 2026, 8:03 AM EDT
Terminated Not applicable Interventional

Use of 3-D Blood Pool Scintigraphy to Guide Left Ventricular Pacing Lead Placement in Patients Requiring Cardiac Resynchronization Therapy

NCT02669290
View directory record Official record
Conditions
Heart Failure, Left Ventricular Dysfunction, Cardiac Resynchronization Therapy
Interventions
Guided, Non-guided
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2020 · Synced Sep 15, 2026, 8:03 AM EDT
Completed Not applicable Interventional Results available

Conduction System Pacing Optimized Therapy

NCT04905290
View directory record Official record
Conditions
Heart Failure
Interventions
Left ventricular coronary sinus (BiV) configuration, Conduction system pacing-only configuration, Conduction System Pacing Optimized Therapy (CSPOT) configuration
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
7
States / cities
Tampa, Florida • Chicago, Illinois • Houma, Louisiana + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2025 · Synced Sep 15, 2026, 8:03 AM EDT
Completed No phase listed Observational

iBeat Wristwatch Validation Study

NCT03711695
View directory record Official record
Conditions
Arrythmia, Cardiac
Interventions
iBeat wristwatch device
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 85 Years
Enrollment
55 participants
Timeline
2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2019 · Synced Sep 15, 2026, 8:03 AM EDT
Recruiting Not applicable Interventional

His-Bundle Corrective Pacing in Heart Failure

NCT05265520
View directory record Official record
Conditions
Right Bundle-Branch Block, Heart Failure, His-bundle Pacing, Cardiac Resynchronization Therapy
Interventions
His-CRT implantation, BIV-CRT implantation
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
14
States / cities
Phoenix, Arizona • Los Angeles, California • Tampa, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 15, 2026, 8:03 AM EDT
Completed No phase listed Observational

Incidence & Predictors of Mechanical Abnormalities of QuickSite® and QuickFlex® Left Ventricular Pacing Leads

NCT01636804
View directory record Official record
Conditions
Left Ventricular Pacing Leads
Interventions
Quicksite, Quickflex
Device
Lead sponsor
Dhanunjaya Lakkireddy, MD, FACC
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2013 · Synced Sep 15, 2026, 8:03 AM EDT
Completed No phase listed Observational

OptiSense™ Performance in Detecting Atrial Episodes

NCT00870324
View directory record Official record
Conditions
Tachyarrhythmias, Atrial Fibrillation
Interventions
OptiSense Lead, Tendril Lead
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Akron, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Sep 15, 2026, 8:03 AM EDT
Completed Phase 2Phase 3 Interventional

EASYTRAK 3 Downsize Lead

NCT00384722
View directory record Official record
Conditions
Heart Failure
Interventions
EASYTRAK 3 Downsize Lead
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 23, 2009 · Synced Sep 15, 2026, 8:03 AM EDT
Recruiting Not applicable Interventional

Mechanistic Clinical Trial of Advanced Imaging for CRT

NCT03398369
View directory record Official record
Conditions
Heart Failure, Systolic
Interventions
CMR/CTA Guidance for CRT
Diagnostic Test
Lead sponsor
University of Virginia
Other
Eligibility
20 Years to 90 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Sep 15, 2026, 8:03 AM EDT
Enrolling by invitation No phase listed Observational

Lead Evaluation for Defibrillation and Reliability Post Approval Study

NCT07005232
View directory record Official record
Conditions
Tachyarrhythmia
Interventions
defibrillation lead
Device
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
52
States / cities
Birmingham, Alabama • Stanford, California • Torrance, California + 45 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 15, 2026, 8:03 AM EDT
Completed Not applicable Interventional

The Effect of Low LEVel TrAgus STimulation on the Electrophysiological Substrate of Patients With Ischemic CardioMyopathy Substrate of Subjects With Ischemic CardioMyopathy

NCT03549468
View directory record Official record
Conditions
Ischemic Cardiomyopathy
Interventions
Low level tragus stimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 90 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Sep 15, 2026, 8:03 AM EDT
Not listed Not applicable Interventional

Electrically Guided Bachmann's Bundle Pacing: A Lead Placement Strategy With Potential Antiarrhythmic Benefits

NCT05153291
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Bachmann's bundle lead placement, Right atrial appendage lead placement
Procedure
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Mar 8, 2022 · Synced Sep 15, 2026, 8:03 AM EDT
Withdrawn Not applicable Interventional

Short Atrioventricular Delay Pacing

NCT01233661
View directory record Official record
Conditions
Chronically (i.e. Implanted for at Least Six Months) Dual-chamber Pacemaker, Stable Cardiac Status (i.e. no Hospitalizations or Cardiac Medication Changes Within 3 Months)
Interventions
short AVD pacing ; prior (stable) programming
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 15, 2026, 8:03 AM EDT