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ClinicalTrials.gov public records Last synced Oct 11, 2026, 1:53 AM EDT

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Showing 217–240 of 861 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pain Education Clear all
Completed Not applicable Interventional

The Implementation of a Post-operative Communication App to Improve Pain Control and Opioid Use

NCT06124079
View directory record Official record
Conditions
Acute Pain
Interventions
OPY interactive messaging service, Standard care
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
3,442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional Results available

Pragmatic Comparative Effectiveness Trial of Evidence-based, On-demand, Digital Behavioral Treatments for Chronic Pain

NCT04933474
View directory record Official record
Conditions
Chronic Pain
Interventions
painTRAINER®, Skills-Based VR
Behavioral · Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
13 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 11, 2026, 1:53 AM EDT
Recruiting Not applicable Interventional

Improving Health for Patients With Chronic Low Back Pain in Rural Communities Through Telerehabilitation

NCT06471920
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Standardized Education, Telerehabilitation
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
434 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Salisbury, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional

A Personalized Self-Management Program for Older Adults With Chronic Pain and Negative Emotions

NCT03487822
View directory record Official record
Conditions
Pain, Chronic, Negative Emotions
Interventions
Path Pain
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 18, 2024 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional

Study of Yoga vs. Health Education for Chronic Pain in Persons Receiving Opioid Agonist Therapy

NCT03022890
View directory record Official record
Conditions
Opioid-Related Disorders, Pain, Chronic
Interventions
hatha yoga, health education
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Fall River, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 9, 2019 · Synced Oct 11, 2026, 1:53 AM EDT
Recruiting Not applicable Interventional

Responding With Evidence and Access for Childhood Headaches

NCT05889624
View directory record Official record
Conditions
Headache, Headache Disorders, Headache, Migraine, Migraine, Migraine Disorders, Migraine With Aura, Migraine Without Aura, Chronic Migraine
Interventions
CBT, Amitriptyline
Behavioral · Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 17 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
15
States / cities
Birmingham, Alabama • Phoenix, Arizona • San Francisco, California + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional Results available

Optimizing Psychotherapy for Older Veterans With Chronic Pain

NCT03918642
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Emotional Awareness and Expression Therapy, Cognitive Behavior Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 95 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2024 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Phase 3 Interventional

Hypnosis to Manage Pain and Symptoms in Patients With Sickle Cell Disease

NCT00393250
View directory record Official record
Conditions
Sickle Cell Disease, Pain Management
Interventions
Hypnosis, Control
Other
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 29, 2021 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional Results available

Reducing the Transition From Acute to Chronic Musculoskeletal Pain Among Older Adults

NCT04118595
View directory record Official record
Conditions
Acute Musculoskeletal Pain, Chronic Pain
Interventions
Educational Video, Telecare, Correspondence with Primary Care Provider
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
50 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 11, 2026, 1:53 AM EDT
Active, not recruiting Not applicable Interventional

Virtual Reality Treatment for Adults With Chronic Back Pain (VRNT)

NCT07033195
View directory record Official record
Conditions
Chronic Pain, Chronic Back Pain, Chronic Lower Back Pain (CLBP)
Interventions
Skills-based Virtual Reality Therapy, Distraction-based Virtual Reality Therapy
Device
Lead sponsor
CognifiSense Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional

Breast Cancer Pre-habilitation and Prospective Surveillance to Prevent, Detect, and Optimize Physical and Function

NCT06081127
View directory record Official record
Conditions
Breast Cancer
Interventions
MOve-ABC, Enhanced Usual Care
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional Results available

Digital Knee Osteoarthritis Mindset Intervention

NCT05698368
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Mindset intervention, Active comparator
Behavioral · Other
Lead sponsor
Stanford University
Other
Eligibility
45 Years and older
Enrollment
458 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Transcranial Direct Current Stimulation on Pain Perception

NCT01860950
View directory record Official record
Conditions
Pain
Interventions
anodal tDCS, cathodal tDCS, sham tDCS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 4, 2018 · Synced Oct 11, 2026, 1:53 AM EDT
Recruiting Not applicable Interventional

A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy

NCT07224945
View directory record Official record
Conditions
Low Back Pain
Interventions
Embedded Emergency Department Physical Therapy, Usual Care
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional Results available

Preventing Persistent Post-Surgical Pain and Opioid Use In At-Risk Veterans: Effect of ACT

NCT02437188
View directory record Official record
Conditions
Persistent Post-surgical Pain, Acceptance and Commitment Therapy, Substance Use Disorder
Interventions
ACT (Acceptance and Commitment Therapy)
Behavioral
Lead sponsor
Barbara A Rakel
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional

Web-MAP Intervention for Youth With Sickle Cell Disease

NCT02511769
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
WEB-MAP Educational Control Group, WEB-MAP CBT
Behavioral
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
11 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional

Meditation Utilizing Signals From Electroencephalography in Chronic Pain (MUSE-PAIN) Study

NCT04944459
View directory record Official record
Conditions
Chronic Pain
Interventions
Muse-S headband; InteraXon Inc., RRID:SCR_014418
Device
Lead sponsor
Center For Interventional Pain and Spine
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Santa Rosa, California • Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Phase 3 Interventional Results available

Efficacy of Web-based Pain Self-management for Adolescents With Juvenile Idiopathic Arthritis

NCT01541917
View directory record Official record
Conditions
Juvenile Idiopathic Arthritis
Interventions
Web-based coping skills training, Online disease education
Behavioral
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
12 Years to 18 Years
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
10
States / cities
San Francisco, California • Chicago, Illinois • Indianopolis, Indiana + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2017 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Phase 1Phase 2 Interventional

Improving Functioning in Persons With Chronic Pain Post-SCI Through Virtual Classroom Education

NCT02561676
View directory record Official record
Conditions
Chronic Pain, Spinal Cord Injuries
Interventions
Education Program Type 1, Education Program Type 2
Other
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Oct 11, 2026, 1:53 AM EDT
Completed No phase listed Observational

Pain Management Protocol for Pediatric Sickle Cell Disease

NCT00386048
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Brief Cognitive-Behavioral Pain Management Training
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
8 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neuroimaging Effects of Cognitive Behavioral Therapy in Fibromyalgia

NCT01345344
View directory record Official record
Conditions
Fibromyalgia
Interventions
Cognitive Behavioral Therapy, Disease Education
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
2
States / cities
Charlestown, Massachusetts • Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 10, 2023 · Synced Oct 11, 2026, 1:53 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Interactions Between Placebo Effects and Mindful Awareness State

NCT07108101
View directory record Official record
Conditions
Placebo Effect, Mindfulness, Pain, Transcranial Direct Current Stimulation (tDCS)
Interventions
tDCS stimulation (sham), tDCS stimulation (real), Mindful state induction, No minfulness induction
Behavioral
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
18 Years to 55 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2029
U.S. locations
1
States / cities
Hanover, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional

Maladaptive Psychosocial Beliefs and Adolescents With Patellofemoral Pain

NCT04752501
View directory record Official record
Conditions
Patellofemoral Pain Syndrome, Knee Pain Chronic, Patellofemoral Syndrome, Anterior Knee Pain Syndrome
Interventions
Psychologically Informed Education, Biomedical Education (Control)
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Oct 11, 2026, 1:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Automatic Multimodal Assessment of Occurrence and Intensity of Pain for Research and Clinical Use

NCT04833244
View directory record Official record
Conditions
Rotator Cuff Injuries
Interventions
Triangular Forearm Support, Placebo
Behavioral
Lead sponsor
Manhattan Physical Medicine and Rehabilitation, LLP
Other
Eligibility
21 Years and older
Enrollment
198 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 11, 2026, 1:53 AM EDT