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ClinicalTrials.gov public records Last synced Sep 7, 2026, 2:42 PM EDT

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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Pain Experience Measures Clear all
Enrolling by invitation Not applicable Interventional

Pilot Study to Evaluate Changes in Intra-Epidermal Nerve Fiber Density (IENFD) in Patients With Small-Fiber Neuropathy

NCT07704931
View directory record Official record
Conditions
Small Fiber Neuropathy
Interventions
Evoke SCS system
Device
Lead sponsor
TriCity Research Center
Industry
Eligibility
19 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Grand Island, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 7, 2026, 2:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Ultrasonic Neuroma Size With Residual Limb Pain in Above-Knee Amputees

NCT00686764
View directory record Official record
Conditions
Neuroma Amputation
Interventions
Observational
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 99 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Sep 7, 2026, 2:42 PM EDT
Completed Not applicable Interventional

Maintenance of Shoulder Health and Function After Spinal Cord Injury

NCT02135978
View directory record Official record
Conditions
Spinal Cord Injury, Shoulder Pain
Interventions
Shoulder home exercise program
Other
Lead sponsor
Rancho Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Downey, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Sep 7, 2026, 2:42 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Multisegmented Foot Motion in Patients With Lateral Ankle Sprains and Chronic Ankle Instability

NCT02697461
View directory record Official record
Conditions
Injuries, Ankle, Sprain of Foot
Interventions
Intrinsic Foot Strengthening, Joint Mobilization
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 50 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Sep 7, 2026, 2:42 PM EDT
Completed No phase listed Observational

The Reproducibility and Consistency of Instrument-assisted Soft Tissue Manipulation

NCT04923633
View directory record Official record
Conditions
Massage
Interventions
Quantifiable Soft Tissue Manipulation (QSTM)
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 75 Years
Enrollment
106 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Sep 7, 2026, 2:42 PM EDT
Not listed Not applicable Interventional

Pain and Opioid Management in Older Adults

NCT05037682
View directory record Official record
Conditions
Pain, Chronic, Opioid Use Disorder
Interventions
Dissemination and Implementation Research
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
1,035 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Sep 7, 2026, 2:42 PM EDT
Completed Not applicable Interventional Results available

Mobile-Based Contingency Management to Promote Daily Self-monitoring in Primary Care Patients

NCT03962491
View directory record Official record
Conditions
Pain, Chronic
Interventions
Daily Self-Monitoring Surveys + Contingency Management, Daily Self-Monitoring Surveys
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 6, 2022 · Synced Sep 7, 2026, 2:42 PM EDT
Enrolling by invitation No phase listed Observational

Enhancing Patient Experience of Pain and Sleep Through Non-Pharmacological Strategies

NCT04428164
View directory record Official record
Conditions
Comfort
Interventions
The Richards-Campbell Sleep Questionnaire (R-CSQ), Revised American Pain Society Outcome Questionnaire (APS-POQ-R)
Other
Lead sponsor
Methodist Health System
Other
Eligibility
20 Years and older
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Sep 7, 2026, 2:42 PM EDT
Recruiting Phase 4 Interventional

Endogenous Opioid Response to Injections

NCT06666621
View directory record Official record
Conditions
Low Back Pain, Zygapophyseal Joint Arthritis
Interventions
Normal saline infusion, Naloxone infusion
Drug
Lead sponsor
Middle Tennessee Research Institute
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 17, 2025 · Synced Sep 7, 2026, 2:42 PM EDT
Completed Not applicable Interventional Results available

Surgical Treatment of Post-surgical Mastectomy Pain Utilizing the Regenerative Peripheral Nerve Interface

NCT04530526
View directory record Official record
Conditions
Post-Mastectomy Chronic Pain Syndrome
Interventions
Regenerative Peripheral Nerve Interface
Procedure
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 7, 2026, 2:42 PM EDT
Not yet recruiting Not applicable Interventional

Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain

NCT06987786
View directory record Official record
Conditions
Spine, Low Back Pain, Neck Pain
Interventions
Massage, Talk-based therapy
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 7, 2026, 2:42 PM EDT
Completed Not applicable Interventional

Management of Pain in Persons With Multiple Sclerosis

NCT00621374
View directory record Official record
Conditions
Multiple Sclerosis, Pain
Interventions
Cognitive Behavioral Therapy (CBT) +Hypnosis (HYP), Cognitive Behavioral Therapy (CBT), Self-Hypnosis Training (HYP), Education Control (CONT)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Sep 7, 2026, 2:42 PM EDT
Recruiting Not applicable Interventional

External Post-Operative Skull Prosthesis to Prevent Sunken Flap Syndrome in Craniectomy Patients

NCT06899711
View directory record Official record
Conditions
Craniectomy, Trephined Syndrome, Traumatic Brain Injury (TBI) Patients, Ischemic Stroke
Interventions
External Cranial Prosthesis
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 7, 2026, 2:42 PM EDT
Completed Not applicable Interventional

MS Symptom Management Study

NCT02474940
View directory record Official record
Conditions
Multiple Sclerosis, Chronic Pain, Fatigue
Interventions
Intervention #1, Intervention #2, Intervention #3
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 25, 2017 · Synced Sep 7, 2026, 2:42 PM EDT
Completed Not applicable Interventional

Feasibility of Video Gaming Technology for Arm Recovery Early Post-stroke

NCT06691880
View directory record Official record
Conditions
Subacute Stroke, Acute Stroke
Interventions
MindPod Dolphin VGT, Bimanual Arm Trainer VGT
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 90 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 7, 2026, 2:42 PM EDT
Completed Not applicable Interventional

The Effect of Music Therapy Intervention on Pain and Anxiety in Adult Patients Undergoing Total Shoulder Arthroplasty

NCT02692768
View directory record Official record
Conditions
Arthritis
Interventions
Live Music Therapy, Recorded Music Therapy, Control
Other
Lead sponsor
April Armstrong
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Sep 7, 2026, 2:42 PM EDT
Completed Not applicable Interventional

Distracting Through Procedural Pain and Distress

NCT04892160
View directory record Official record
Conditions
Chronic Illness, Hematologic Malignancy, Bone Marrow Transplant Infection, Oncology, Sickle Cell Disease
Interventions
Guided Imagery, Virtual Reality
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
8 Years to 25 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Milwaukee, Wisconsin • Wauwatosa, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 18, 2021 · Synced Sep 7, 2026, 2:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Internet-Based Pain Coping Skills Training for Patients With Lupus

NCT03933839
View directory record Official record
Conditions
Lupus Erythematosus, Systemic
Interventions
PainCOACH
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Sep 7, 2026, 2:42 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

COA-APTIC Cognitive Interview Study of Caregiver and Clinician Assessment of Acute Pain in Infants and Young Children

NCT06164028
View directory record Official record
Conditions
Acute Pain
Interventions
cognitive interview
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 7, 2026, 2:42 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Multimodal Sleep Pathway for Shoulder Arthroplasty

NCT03269760
View directory record Official record
Conditions
Sleep Disturbance, Shoulder Arthritis, Arthroplasty Complications, Perioperative/Postoperative Complications
Interventions
Zolpidem
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 26, 2020 · Synced Sep 7, 2026, 2:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Methods for Ascertainment of Gout Flares -A Pilot Study

NCT02855437
View directory record Official record
Conditions
Gout
Interventions
IVR (Phone call), RheumPro (Smartphone application)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 27, 2019 · Synced Sep 7, 2026, 2:42 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Muscle Function After Childbirth

NCT05073224
View directory record Official record
Conditions
Postpartum, Muscle Fatigue, Force Steadiness, Nulligravid, Muscle Weakness
Interventions
Active Straight Leg Raise Test, Active Straight Leg Raise Fatigue Task, Lower Extremity Strength Testing, Ultrasound imaging of abdominal wall
Diagnostic Test · Other
Lead sponsor
Carroll University
Other
Eligibility
20 Years to 35 Years · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Waukesha, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 7, 2026, 2:42 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Quality Improvement re: Choosing Wisely Back Pain Measures

NCT05413070
View directory record Official record
Conditions
Back Pain, Low, Back Pain, Back Pain Lower Back Chronic
Interventions
Multimodal approach to QI for Low-Value Care
Behavioral
Lead sponsor
Carilion Clinic
Other
Eligibility
Not listed
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Sep 7, 2026, 2:42 PM EDT
Completed Not applicable Interventional Results available

PROMIS Measures in Primary Care Practice

NCT02383862
View directory record Official record
Conditions
Sleep, Pain, Anxiety, Depression, Fatigue
Interventions
Feedback Group
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 15, 2017 · Synced Sep 7, 2026, 2:42 PM EDT