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ClinicalTrials.gov public records Last synced Oct 27, 2026, 5:57 PM EDT

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Showing 25–48 of 185 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pain Information Control Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Migraine in Adolescents

NCT05654012
View directory record Official record
Conditions
Migraine
Interventions
MRI, Thermal Stimuli, Pressure stimuli, Pain ratings, Pressure pain thresholds (PPT), Conditioned pain modulation (CPM) efficiency, Hormonal assessment, Migraine-related measures, Neural assessments, Pubertal status
Device · Behavioral · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
10 Years to 13 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 27, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional

Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain

NCT06991205
View directory record Official record
Conditions
Orthopedic Disorder, Nontraumatic Injury, Upper Extremity Pain, Risky Substance Use
Interventions
Web-TIRELESS, Web-MEUC
Behavioral · Other
Lead sponsor
Jafar Bakhshaie
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 27, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

VibraCool Device to Reduce Pain and Opioid Use After Anterior Cruciate Ligament Reconstruction (ACLR)

NCT06456268
View directory record Official record
Conditions
ACL, Opioid Use, Cryotherapy Effect, Vibration; Exposure, Pain, Postoperative
Interventions
VibraCool mechanical stimulation and neuromodulatory therapeutic device, Cryocompression (Game Ready, Bregs) device, Standard ice packs
Device
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Cardiac Rehabilitation Program in Peripheral Arterial Disease

NCT03251391
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Cardiac Rehabilitation Program, Conventional Therapy
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Physiatrist Ergonomic Intervention on Work Related Musculoskeletal Pain in Surgeons

NCT05946018
View directory record Official record
Conditions
Musculoskeletal Pain, Work Related Stress, Quality of Life, Grip
Interventions
Educational video on ergonomics, Verbal physical therapy coaching sessions
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Phase 2 Interventional

Managing Recurrent Abdominal Pain

NCT00494260
View directory record Official record
Conditions
Abdominal Pain
Interventions
Social Learning and Cognitive Behavioral Therapy (SLCBT), Education Support (ES)
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
7 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
2
States / cities
Morristown, New Jersey • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 31, 2016 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional Results available

Visualizations to Improve Pain Communication Between Patients, Interpreters, and Providers

NCT04975789
View directory record Official record
Conditions
Communication, Pain
Interventions
InfoViz
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
13 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 7, 2024 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional Results available

Advancing Symptom Alleviation With Palliative Treatment

NCT02713347
View directory record Official record
Conditions
Heart Failure, Pulmonary Disease, Chronic Obstructive, Emphysema, Pulmonary Fibrosis, Interstitial Lung Disease
Interventions
ADAPT Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
2
States / cities
Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 9, 2024 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Management of Pain in Persons With Multiple Sclerosis

NCT00621374
View directory record Official record
Conditions
Multiple Sclerosis, Pain
Interventions
Cognitive Behavioral Therapy (CBT) +Hypnosis (HYP), Cognitive Behavioral Therapy (CBT), Self-Hypnosis Training (HYP), Education Control (CONT)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 16, 2013 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional Results available

Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33)

NCT04533711
View directory record Official record
Conditions
Osteoarthritis
Interventions
OA-PCP Intervention, Attention Control
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Chest Pain Observation Unit Risk Reduction Trial

NCT00536224
View directory record Official record
Conditions
Chest Pain
Interventions
Full counseling, Minimal counseling
Behavioral
Lead sponsor
David A Katz
Other
Eligibility
30 Years to 100 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 26, 2018 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional

The Pain App Study: A Novel Shared Decision Making Tool for People With Chronic Pain

NCT03425266
View directory record Official record
Conditions
Chronic Pain
Interventions
Interactive decision support tool
Other
Lead sponsor
Shared Decision Making Resources
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Georgetown, Maine
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Single Session Pain Psychology Treatment: Comparative Efficacy & Mechanisms

NCT03167086
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
"Empowered Relief" (ER), Cognitive Behavioral Therapy (CBT), Health Education (HE)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2020 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of the Avulux® Lenses as an Aid in Reducing the Impact of Migraine Headaches

NCT04341298
View directory record Official record
Conditions
Migraine
Interventions
11-point pain scale, Headache diary, Avulux®, Sham Avulux®
Other · Device
Lead sponsor
Avulux, Inc.
Industry
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
3
States / cities
Minneapolis, Minnesota • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 9, 2023 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mind-body Interventions for Healthy Aging

NCT03626532
View directory record Official record
Conditions
Aging
Interventions
Mindfulness-Based Stress Reduction (MBSR), Lifestyle Education (LifeEd)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
65 Years to 85 Years
Enrollment
173 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional

Collaborative Care to Alleviate Symptoms and Adjust to Illness in Chronic Heart Failure (CASA) Trial

NCT01739686
View directory record Official record
Conditions
Chronic Heart Failure
Interventions
CASA Intervention
Other
Lead sponsor
Denver Research Institute
Other
Eligibility
18 Years and older
Enrollment
317 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
3
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional Results available

Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents

NCT01118988
View directory record Official record
Conditions
Irritable Bowel Syndrome (IBS), Functional Abdominal Pain, Fibromyalgia, Complex Regional Pain Syndrome (CRPS), Myofacial Pain, Chronic Daily Headaches, Migraine Headaches, Chronic Pain
Interventions
Mentorship
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 18 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Postoperative Opt-In Narcotic Treatment Study

NCT04710069
View directory record Official record
Conditions
Postoperative Pain, Narcotic Use, Analgesia, Endocrine Surgery, Opioid Use, Opioid Abuse
Interventions
POINT
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2021 · Synced Oct 27, 2026, 5:57 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Chia on Overweight/Obese Women

NCT03233906
View directory record Official record
Conditions
Obesity, Eating Behavior, Mood, Glucose, Dietary Modification
Interventions
Chia Seeds- Salvia Hispanica
Dietary Supplement
Lead sponsor
California State Polytechnic University, Pomona
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated May 11, 2018 · Synced Oct 27, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional

Weight Management After Cancer for Survivors in Rural Communities

NCT07426952
View directory record Official record
Conditions
Breast Cancer Survivorship, Weight Management, Cardiovascular (CV) Risk, Breast Cancer
Interventions
WeCan-Rural Program
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
5
States / cities
Durham, North Carolina • Henderson, North Carolina • Laurinburg, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 27, 2026, 5:57 PM EDT
Not listed Not applicable Interventional

Virtual Reality for Alleviation of Peripheral IV Placement-Associated Discomfort

NCT03740607
View directory record Official record
Conditions
Procedural Anxiety, Procedural Pain, Perioperative Care
Interventions
Virtual reality, Peripheral intravenous catheter placement
Device · Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2021 · Synced Oct 27, 2026, 5:57 PM EDT
Completed Not applicable Interventional

HOnest Placebos With Explanations: Evaluating Open-Label Placebos for Chronic Pain

NCT06931158
View directory record Official record
Conditions
Chronic Low-back Pain, Chronic Pain
Interventions
Open-label Placebo, Standard Rationale, Mindfulness, Control Rationale
Drug · Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 89 Years
Enrollment
327 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 27, 2026, 5:57 PM EDT
Terminated Not applicable Interventional

Preoperative Education in Hand and Wrist Surgery

NCT05237531
View directory record Official record
Conditions
Distal Radius Fracture
Interventions
Standardized Preoperative Education, Standard of care, Preoperative and postoperative questionnaires
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 27, 2026, 5:57 PM EDT
Recruiting Not applicable Interventional

Brief Digitally-Enhanced Intervention for Reducing Alcohol Use During MOUD

NCT06718491
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Managing Physical Reactions to Overwhelming Emotions (IMPROVE), Health Education Training (HET)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 27, 2026, 5:57 PM EDT