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ClinicalTrials.gov public records Last synced Sep 3, 2026, 8:41 AM EDT

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Showing 1–24 of 776 matching trials from the live ClinicalTrials.gov search.
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Recruiting Not applicable Interventional

Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)

NCT05792189
View directory record Official record
Conditions
Distal Femur Fracture
Interventions
Timed Up and Go Test on subjects with ORIF of distal femur fractures, Koos Jr assesment on subjects with ORIF of distal femur fractures, Timed Up and Go Test on subjects with DFR of distal femur fracture, Koos Jr assesment on subjects with DFR of distal femur fracture
Other
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 3, 2026, 8:41 AM EDT
Recruiting Not applicable Interventional

Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection Techniques

NCT06892496
View directory record Official record
Conditions
Mucosal Erosion, Gingival Recession
Interventions
Visual Analog scale (VAS) questionnaire, Vacuum-formed retainer (VFR) technique, 3-D printed acrylic resin stent (3DS) technique, Flowable resin composite stent (FRC) technique, Photographs of the patient's palate, Measuring graft dimensions, Chairside Polymer Stent
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 3, 2026, 8:41 AM EDT
Recruiting Not applicable Interventional

Online Social Learning Program for Parents With Irritable Bowel Syndrome: Raising Resilient Children

NCT05730491
View directory record Official record
Conditions
Irritable Bowel Syndrome, Abdominal Pain
Interventions
Social Learning and Cognitive Behavioral Therapy (SLCBT), Attention Education Control
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
18 Years and older
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 3, 2026, 8:41 AM EDT
Terminated Phase 4 Interventional

Effect of Perioperative Acetaminophen Dosing on Patients Undergoing Surgical Treatment of Basilar Thumb Arthritis

NCT05556356
View directory record Official record
Conditions
Carpometacarpal Osteoarthritis
Interventions
Acetaminophen, Placebo: Multivitamin
Drug · Other
Lead sponsor
Indiana Hand to Shoulder Center
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Sep 3, 2026, 8:41 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Teachable Moment Brief Intervention for Suicide Attempt Survivors in an Inpatient Setting

NCT03600532
View directory record Official record
Conditions
Suicide, Attempted
Interventions
Teachable Moment Brief Intervention (TMBI)
Behavioral
Lead sponsor
University of Tulsa
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Sep 3, 2026, 8:41 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

BRIDGE Device for Treatment of Opioid Withdrawal

NCT04162145
View directory record Official record
Conditions
Opioid Withdrawal, Pain, Craving
Interventions
Active BRIDGE device placement, Inactive BRIDGE device placement
Device
Lead sponsor
BrightView LLC
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Sep 3, 2026, 8:41 AM EDT
Completed Not applicable Interventional

Ear Electro-stimulation for Chronic Pelvic Pain

NCT01345331
View directory record Official record
Conditions
Endometriosis
Interventions
Real stimulation VS Sham
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 64 Years · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 1, 2011 · Synced Sep 3, 2026, 8:41 AM EDT
Completed Not applicable Interventional Results available

A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 3)

NCT04751526
View directory record Official record
Conditions
Pain Management
Interventions
BreEStim 240, EStim 240
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Sep 3, 2026, 8:41 AM EDT
Active, not recruiting Not applicable Interventional

Developing and Evaluating a Machine-Learning Opioid Overdose Prediction & Risk-Stratification Tool in Primary Care

NCT06810076
View directory record Official record
Conditions
Opiate Overdose, Opioid-Related Disorders, Narcotic-Related Disorders, Substance-related Disorders, Chemically-Induced Disorders, Mental Disorders
Interventions
Machine Learning-Based Clinical Decision Support: Overdose Prevention Alert (OPA) Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
674 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 3, 2026, 8:41 AM EDT
Recruiting Phase 2 Interventional

Combined THC and CBD for OUD and Chronic Pain

NCT06544291
View directory record Official record
Conditions
Chronic Pain, Opioid Use Disorder
Interventions
CBD 300mg, CBD 600mg, Placebo 0mg
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 3, 2026, 8:41 AM EDT
Not listed Not applicable Interventional

Opioid Counseling in Pain Management

NCT03985358
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Opioid counseling plus standard of care instructions
Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Sep 3, 2026, 8:41 AM EDT
Completed Phase 2 Interventional Results available

Study of Diclofenac Capsules to Treat Dental Pain

NCT00985439
View directory record Official record
Conditions
Dental Pain
Interventions
Diclofenac Test (lower dose), Diclofenac Test (upper dose), Celecoxib 400 mg, Placebo
Drug
Lead sponsor
Iroko Pharmaceuticals, LLC
Industry
Eligibility
18 Years to 50 Years
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2012 · Synced Sep 3, 2026, 8:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise-induced Hypoalgesia After Comparative Forms of Exercise

NCT01883895
View directory record Official record
Conditions
Pain
Interventions
Forgionei-Barber pressure-pain stimulator, Concentric Exercise, isometric exercise
Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 23, 2017 · Synced Sep 3, 2026, 8:41 AM EDT
Completed Not applicable Interventional

MUSic Therapy to Improve Quality Of Life in Sickle Cell Disease (MUSIQOLS)

NCT03556657
View directory record Official record
Conditions
Sickle Cell Disease, Chronic Pain
Interventions
Music Therapy
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 5, 2019 · Synced Sep 3, 2026, 8:41 AM EDT
Completed Not applicable Interventional Results available

Intraoperative Echocardiography in Low-Risk CABG Surgery

NCT06154265
View directory record Official record
Conditions
Heart Diseases, Coronary Artery Disease, Chest Pain, Stenosis Coronary, STEMI
Interventions
TEE probe
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 100 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 3, 2026, 8:41 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

ED90 of Bupivacaine After Lidocaine Test Dose With DPE and EPL

NCT06146842
View directory record Official record
Conditions
Labor Pain
Interventions
Bupivacaine Hydrochloride
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 3, 2026, 8:41 AM EDT
Active, not recruiting Not applicable Interventional

CYP2D6 Genotype-guided Management of Opioid Analgesics in Patients Undergoing Elective Ventral Hernia Repairs

NCT06565546
View directory record Official record
Conditions
Ventral Hernia
Interventions
Opioid pain medication prescribed based on CYP2D6 genotype testing PLUS Acetaminophen and Gabapentin, Acetaminophen and Gabapentin: standard postoperative pain medications
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 3, 2026, 8:41 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transdiagnostic Cognitive Biomarkers

NCT04864080
View directory record Official record
Conditions
Pain, Depression
Interventions
Computer game/task, Health surveys online
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 3, 2026, 8:41 AM EDT
Completed No phase listed Observational

Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES)

NCT01117506
View directory record Official record
Conditions
Coronary Artery Disease, Chest Pain, Cardiovascular Diseases, Coronary Heart Disease, Angina Pectoris, CAD, CVD, CHD
Interventions
Corus CAD (ASGES)
Diagnostic Test
Lead sponsor
CardioDx
Industry
Eligibility
35 Years to 90 Years
Enrollment
581 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
7
States / cities
Long Beach, California • Roseville, California • Boulder, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2019 · Synced Sep 3, 2026, 8:41 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Virtual Physical Therapy Support for Runners

NCT05994833
View directory record Official record
Conditions
Musculoskeletal Complication
Interventions
VPT
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 3, 2026, 8:41 AM EDT
Completed Not applicable Interventional Results available

Randomized Investigation of Chest Pain Diagnostic Strategies

NCT01035047
View directory record Official record
Conditions
Acute Coronary Syndrome, Chest Pain
Interventions
Clinical decision unit care, coupled with cardiac MRI
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2018 · Synced Sep 3, 2026, 8:41 AM EDT
Completed Phase 2 Interventional Results available

Sumatriptan as Treatment for Post-traumatic Headache

NCT01854385
View directory record Official record
Conditions
Post-traumatic Headache
Interventions
Sumatriptan 100 mg
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Sep 3, 2026, 8:41 AM EDT
Completed Phase 2 Interventional Results available

Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers

NCT01740414
View directory record Official record
Conditions
Opioid Abuse, Opioid Dependence
Interventions
MN-166 (50 mg) First, Placebo First
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 55 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 16, 2017 · Synced Sep 3, 2026, 8:41 AM EDT
Completed No phase listed Observational Results available

Congenital Sucrase-Isomaltase Deficiency (CSID) Genetic Prevalence Study (GPS)

NCT01914003
View directory record Official record
Conditions
Congenital Sucrase-isomaltase Deficiency (CSID)
Interventions
Not listed
Lead sponsor
QOL Medical, LLC
Industry
Eligibility
Up to 18 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
19
States / cities
Los Angeles, California • Oakland, California • Aurora, Colorado + 16 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 3, 2026, 8:41 AM EDT