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ClinicalTrials.gov public records Last synced Oct 23, 2026, 2:25 AM EDT

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Showing 505–528 of 788 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pain testing Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Water-friendly Virtual Reality and Brief Thermal Pain

NCT04245475
View directory record Official record
Conditions
Pain, Acute
Interventions
Virtual Reality psychological pain reduction
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Oct 23, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MusculRA: The Effects of Rheumatoid Arthritis on Skeletal Muscle Biomechanics

NCT04226131
View directory record Official record
Conditions
Rheumatoid Arthritis, Healthy Controls
Interventions
Blood Draw, Disease Activity (DAS-28) Assessment, Skeletal Muscle Mitochondrial Respiratory Capacity, Muscle Biopsy, Body Composition, Cardiopulmonary Exercise Test (CPET), Strength Testing, Questionnaires, Skeletal Muscle Biomechanical Property Assessment
Other
Lead sponsor
Duke University
Other
Eligibility
25 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Oct 23, 2026, 2:25 AM EDT
Withdrawn No phase listed Observational

An Investigation of the Association Between Helicobacter Pylori Infection and Abdominal Pain in Cystic Fibrosis Patients

NCT00765401
View directory record Official record
Conditions
Cystic Fibrosis, Abdominal Pain, Helicobacter Pylori Infection
Interventions
Not listed
Lead sponsor
Penn State University
Other
Eligibility
5 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 23, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Injury Prevention & Rehabilitation in Military Personnel

NCT02077413
View directory record Official record
Conditions
Muscle Injury
Interventions
Healthy Muscle Group, Stretch-Contract Pre-rehabilitation Group, Stretch-Contract Control Group, Muscle Atrophy
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 40 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 17, 2016 · Synced Oct 23, 2026, 2:25 AM EDT
Completed Not applicable Interventional

ProspEctive First Evaluation in Chest Pain Trial

NCT01604655
View directory record Official record
Conditions
Chest Pain, Shortness of Breath, Suspected Acute Coronary Syndrome
Interventions
Coronary CT Angiography, Stress Test
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
45 Years and older
Enrollment
411 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 8, 2016 · Synced Oct 23, 2026, 2:25 AM EDT
Completed Not applicable Interventional

Scrambler Therapy for the Reduction of Chemotherapy-Induced Neuropathic Pain

NCT04239976
View directory record Official record
Conditions
Chemotherapy-Induced Peripheral Neuropathy, Malignant Neoplasm
Interventions
FitBit, Gait Assessment Test, MC5-A Scrambler Therapy, Quality-of-Life Assessment, Quantitative Sensory Testing, Questionnaire Administration
Device · Other · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Oct 23, 2026, 2:25 AM EDT
Recruiting No phase listed Observational

Psychophysical Studies of Cancer Therapy Pain

NCT00515060
View directory record Official record
Conditions
Advanced Cancer, Pain
Interventions
Sensory Tests
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 23, 2026, 2:25 AM EDT
Completed Not applicable Interventional

Digital Behavioral Pain Medicine for Orthopedic Trauma Surgery Patients

NCT03764839
View directory record Official record
Conditions
Orthopedic Trauma Surgery Patients
Interventions
Perioperative Digital Behavioral Pian Medicine "My Surgical Success"
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2020 · Synced Oct 23, 2026, 2:25 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A118G SNP and OPRM1 Gene Opioid-Mediated Effects in Humans

NCT02360371
View directory record Official record
Conditions
Opioid Sensitivity, Individual Difference, Abuse Opioids
Interventions
Within-subject test of blinded study medication
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Oct 23, 2026, 2:25 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Football Players Health Study In Person Assessments Study

NCT03866564
View directory record Official record
Conditions
Cardiac Dysfunction, Neurocognitive Disease, Chronic Pain, Sleep Apnea
Interventions
Echocardiography, Neuropsychological Testing, Quantitative Sensory Testing, Nocturnal Polysomnography
Diagnostic Test
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
24 Years to 55 Years · Male only
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 23, 2026, 2:25 AM EDT
Completed Not applicable Interventional Results available

PROspective Multicenter Imaging Study for Evaluation of Chest Pain

NCT01174550
View directory record Official record
Conditions
Chest Pain
Interventions
Coronary Angiography, Stress Echocardiogram, Nuclear Stress Test, Exercise Electrocardiogram
Procedure
Lead sponsor
Duke University
Other
Eligibility
45 Years and older
Enrollment
10,003 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 29, 2016 · Synced Oct 23, 2026, 2:25 AM EDT
Not yet recruiting Not applicable Interventional

Arm Elevation for Prevention of Propofol Injection Pain

NCT07785674
View directory record Official record
Conditions
Propofol Injection Pain
Interventions
Passive arm elevation, Normal saline, Lidocaine, Propofol, Sham arm elevation
Procedure · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 23, 2026, 2:25 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Natural History of Shoulder Pathology in Manual Wheelchair Users

NCT02600910
View directory record Official record
Conditions
Paraplegia, Spinal Cord Injuries, Shoulder Pain, Tendinopathy
Interventions
Not listed
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
2
States / cities
Rochester, Minnesota • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 23, 2026, 2:25 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Exploring Pain Modulation With TMS and Repeated Pain Conditioning in Healthy Individuals

NCT06726018
View directory record Official record
Conditions
Healthy Adult
Interventions
Conditioned Pain Modulation (CPM)
Behavioral
Lead sponsor
Priyanka Rana, PT, MPT, PhD
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 23, 2026, 2:25 AM EDT
Terminated Phase 2 Interventional Results available

LCI-NOS-PAIN-001: A Prospective, Pharmacogenomic-Driven Study of Pain Management in Oncology Outpatients

NCT02542397
View directory record Official record
Conditions
Malignant Tumor of Ill-defined Site
Interventions
Pharmacogenomic Testing
Genetic
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 3, 2022 · Synced Oct 23, 2026, 2:25 AM EDT
Completed Phase 3 Interventional Results available

Study of Diclofenac Capsules to Treat Osteoarthritis Pain

NCT01461369
View directory record Official record
Conditions
Osteoarthritis
Interventions
Diclofenac, Placebo
Drug
Lead sponsor
Iroko Pharmaceuticals, LLC
Industry
Eligibility
40 Years and older
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
40
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Anaheim, California + 31 more
Source: ClinicalTrials.gov public record
Updated May 26, 2014 · Synced Oct 23, 2026, 2:25 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Trigger Point Injection for Myofascial Pain Syndrome in the Low Back: A Randomized Controlled Trial

NCT04704297
View directory record Official record
Conditions
Low Back Pain, Myofascial Pain Syndrome Lower Back
Interventions
Treatment of Myofascial Pain Syndrome in the low back. This intervention will be based on outcomes of the medications listed below., Evaluation of functional ability using a patient centered functional score known as the Modified Oswestry Disability Index (MODI). The intervention will be based on outcomes of medications below., Following up with participants 60-72 hours after treatment in the Emergency Department. This intervention will be based on outcomes of the medications listed below.
Drug
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 23, 2026, 2:25 AM EDT
Completed Phase 1 Interventional

The Pathophysiology of Orthostatic Hypotension

NCT00748059
View directory record Official record
Conditions
Autonomic Nervous System Diseases, Orthostatic Hypotension, Dopamine Beta-Hydroxylase Deficiency, Orthostatic Intolerance
Interventions
Standing or upright tilt, Microneurography, QSweat, neck cuff stimulation, phenylephrine,isoproterenol,nitroprusside,propranolol,edrophonium,atropine,tyramine, clonidine,yohimbine,metoclopramide,alpha-methyldopa, BodPod, Eye exam, Sleep study, Pain response testing, Metabolic chamber, Brain function studies, Bicycle Exercise Test
Procedure · Device · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
12 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Oct 23, 2026, 2:25 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Explosive Synchronization of Brain Network Activity in Chronic Pain

NCT04606095
View directory record Official record
Conditions
Fibromyalgia, Healthy Volunteers
Interventions
EEG, Neuroimaging EEG/fMRI (Aim 1), HD-tDCS treatments, Sham HD-tDCS treatments, Neuroimaging EEG/fMRI (Aim 3)
Diagnostic Test · Device
Lead sponsor
University of Michigan
Other
Eligibility
19 Years to 74 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 23, 2026, 2:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mirthful Laughter and Muscle Soreness / Pain

NCT02896075
View directory record Official record
Conditions
Pain
Interventions
30 Minute Comedy Video, 30 Minute Documentary Video
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
20 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 23, 2026, 2:25 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Stellate Ganglion Block for COVID-19-Induced Olfactory Dysfunction

NCT05445921
View directory record Official record
Conditions
Anosmia, Hyposmia, Parosmia, Olfactory Disorder
Interventions
Stellate Ganglion Block
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 23, 2026, 2:25 AM EDT
Completed Phase 1 Interventional

Study of the Treatment of Experimental Pain in Opioid Dependent Persons on Methadone or Buprenorphine Maintenance

NCT01642030
View directory record Official record
Conditions
Opioid Dependence, Pain, Addiction
Interventions
Placebo, Hydromorphone, Buprenorphine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Oct 23, 2026, 2:25 AM EDT
Withdrawn Phase 2Phase 3 Interventional

GetHealthy-OA: A Program to Improve Pain and Function for Patients With Knee Osteoarthritis, Obesity, and Depression

NCT05482672
View directory record Official record
Conditions
Knee Osteoarthritis, Obese, Depression
Interventions
Fisetin, GetHealthy-OA mind-body program, Placebo oral capsule, Health education booklet
Drug · Behavioral
Lead sponsor
Cale Andrew Jacobs, PhD
Other
Eligibility
40 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
2
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 1, 2023 · Synced Oct 23, 2026, 2:25 AM EDT
Recruiting Not applicable Interventional

A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy

NCT07224945
View directory record Official record
Conditions
Low Back Pain
Interventions
Embedded Emergency Department Physical Therapy, Usual Care
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 23, 2026, 2:25 AM EDT