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ClinicalTrials.gov public records Last synced Oct 20, 2026, 11:38 AM EDT

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Showing 481–504 of 7,138 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pain treatment Clear all
Completed Phase 2 Interventional Results available

OCS-01 in Treating Inflammation and Pain in Post-cataract Patients

NCT04130802
View directory record Official record
Conditions
Inflammation Corneal, Pain, Postoperative
Interventions
OCS-01 - Dexamethasone Cyclodextrin Nanoparticle Ophthalmic Suspension 1.5% mg/mL, Placebo
Drug
Lead sponsor
Oculis
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
4
States / cities
Petaluma, California • Roseburg, Oregon • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 20, 2026, 11:38 AM EDT
Recruiting Phase 3 Interventional

Prehospital Analgesia INtervention Trial (PAIN)

NCT05437575
View directory record Official record
Conditions
Traumatic Injury
Interventions
Ketamine Hydrochloride, Fentanyl Citrate
Drug
Lead sponsor
Jason Sperry
Other
Eligibility
18 Years and older
Enrollment
994 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
11
States / cities
San Diego, California • San Francisco, California • Camden, New Jersey + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of XT-150 for Facet Joint Osteoarthritis Pain

NCT05196919
View directory record Official record
Conditions
Facet Joint Pain, Back Pain, Inflammation
Interventions
XT-150, Placebo
Biological
Lead sponsor
Xalud Therapeutics, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Napa, California • Santa Monica, California • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Cryoanalgesia to Treat Post-Amputation Phantom Limb Pain: A Department of Defense Funded Multicenter Study

NCT03449667
View directory record Official record
Conditions
Post-Amputation Phantom Limb Pain
Interventions
Cryoneurolysis, Sham Comparator
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
6
States / cities
Palo Alto, California • San Diego, California • Gainesville, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2023 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Phase 4 Interventional Results available

Analgesia After Total Shoulder Arthroplasty

NCT01782872
View directory record Official record
Conditions
Total Shoulder Arthroplasty
Interventions
Interscalene Block (ISB) - 0.375% Ropivacaine + additives, Interscalene Block (ISB) - 0.2% Ropivacaine + additives, Interscalene Block (ISB) - 0.1% Ropivacaine + additives, Interscalene Block (ISB) - Systemic Control
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 18, 2016 · Synced Oct 20, 2026, 11:38 AM EDT
Terminated No phase listed Interventional Results available

Feasibility of Bridge for Post-Operative Pain Management in Hip Arthroplasty

NCT05017701
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Bridge device, Sham device
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Outcomes of CPM Usage Following Arthroscopic Acetabular Labral Repair

NCT03407612
View directory record Official record
Conditions
Femoro Acetabular Impingement, Pain, Postoperative, Hip Labral Tear
Interventions
Continuous Passive Motion
Device
Lead sponsor
Ohio State University
Other
Eligibility
14 Years to 50 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 20, 2026, 11:38 AM EDT
Recruiting Not applicable Interventional

Trial for Treating Painful Degenerative Disc Disease

NCT05287867
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Platelet-rich plasma (PRP), Platelet lysate (PL), and Platelet Poor Plasma (PPP), Sham procedure
Biological · Other
Lead sponsor
Regenexx, LLC
Industry
Eligibility
25 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Broomfield, Colorado • Lone Tree, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 20, 2026, 11:38 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study

NCT06036095
View directory record Official record
Conditions
Neurocognitive Disorders, Anesthesia, Post-operative Delirium, Post-operative Cognitive Dysfunction
Interventions
Sevoflurane, Propofol
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
70 Years to 110 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 8, 2024 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Brief Cognitive Behavioral Therapy for Chronic Pain

NCT03490981
View directory record Official record
Conditions
Chronic Pain, Musculoskeletal Pain
Interventions
Treatment as usual (TAU), Brief Cognitive Behavioral Therapy for Chronic Pain (Brief CBT-CP)
Other · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 79 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2021 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrating Patient Reported Outcomes (I-PRO) Study for Multidisciplinary Pain Care

NCT02188667
View directory record Official record
Conditions
Chronic Noncancer Pain
Interventions
Providers of Novel Care, Providers of Usual Care
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 89 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
4
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 30, 2016 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Duloxetine in Osteoarthritis (OA) Pain

NCT01558700
View directory record Official record
Conditions
Osteoarthritis
Interventions
Duloxetine, Sugar pill
Drug
Lead sponsor
Northwestern University
Other
Eligibility
40 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 29, 2014 · Synced Oct 20, 2026, 11:38 AM EDT
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

NCT06096597
View directory record Official record
Conditions
Interstitial Cystitis, Painful Bladder Syndrome, Painful Bladder Syndrome (PBS)
Interventions
Clarix Flo, Placebo
Drug
Lead sponsor
David Sheyn
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Clevleand, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Phase 2 Interventional Results available

Mesalamine Granules for Irritable Bowel Syndrome (IBS) With Diarrhea

NCT01177410
View directory record Official record
Conditions
Irritable Bowel Syndrome With Diarrhea
Interventions
Placebo, Mesalamine Granules 750 mg, Mesalamine Granules 1500 mg
Drug
Lead sponsor
Bausch Health Americas, Inc.
Industry
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
20
States / cities
Sherwood, Arkansas • Anaheim, California • Sacramento, California + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2019 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

M-gCBT for Women With Provoked Localized Vulvodynia

NCT02919813
View directory record Official record
Conditions
Provoked Localized Vulvodynia
Interventions
Mindfulness Based Group Cognitive BehaviorTherapy, Educational Seminars
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 6, 2022 · Synced Oct 20, 2026, 11:38 AM EDT
Terminated Phase 2 Interventional Results available

A Placebo-controlled Crossover Trial Using Cyproheptadine To Treat Children With Functional Abdominal Pain

NCT01675050
View directory record Official record
Conditions
Functional Abdominal Pain
Interventions
Cyproheptadine, sugar pill
Drug
Lead sponsor
University of Michigan
Other
Eligibility
8 Years to 18 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Naproxen for Pain Control With Intrauterine Device Insertion

NCT02388191
View directory record Official record
Conditions
Contraception
Interventions
Naproxen sodium, Placebo tablet
Drug · Other
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 22, 2017 · Synced Oct 20, 2026, 11:38 AM EDT
Recruiting Early Phase 1 Interventional

Psilocybin-facilitated Treatment for Chronic Pain

NCT05068791
View directory record Official record
Conditions
Fibromyalgia, Primary
Interventions
Psilocybin, Dextromethorphan
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
25 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Transcutaneous Electrical Stimulation for Spasticity in Patients With Primary Lateral Sclerosis

NCT06012110
View directory record Official record
Conditions
Primary Lateral Sclerosis
Interventions
Transcutaneous electrical stimulation
Device
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Davie, Florida
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Manual Therapy Provide Immediate Improvement in Lumbar Range of Motion?

NCT05926674
View directory record Official record
Conditions
N/A Healthy Individuals
Interventions
Myofascial Release, Light Touch Contact
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of B. Adolescentis iVS-1 Probiotic on Gastrointestinal Outcomes

NCT07408518
View directory record Official record
Conditions
Digestive Disease, Gut Health
Interventions
Probiotic, Placebo
Dietary Supplement · Other
Lead sponsor
Synbiotic Health
Industry
Eligibility
18 Years to 75 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 20, 2026, 11:38 AM EDT
Recruiting Not applicable Interventional

Autonomic Neural Blockade in Bariatric Surgery

NCT07104825
View directory record Official record
Conditions
Bariatric Surgery Candidate, Pain, Postoperative, Nausea and Vomiting, Postoperative, Opioid Use
Interventions
Intraoperative autonomic neural blockade (ANB), Laparoscopic Standard of Care Abdominal Wall Block
Procedure
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 90 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 20, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Physical Activity for Older Adults Chronic Low Back Pain

NCT02327325
View directory record Official record
Conditions
Low Back Pain
Interventions
Physical Activity, Cognitive Behavioral Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Oct 20, 2026, 11:38 AM EDT
Terminated Phase 4 Interventional Results available

Drug Concentration and Volume on Adequate Labor Analgesia With PIEB

NCT03553576
View directory record Official record
Conditions
Pain, Anesthesia, Labor Pain
Interventions
Low volume bolus, High volume bolus
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Oct 20, 2026, 11:38 AM EDT