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ClinicalTrials.gov public records Last synced Oct 22, 2026, 8:09 PM EDT

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Showing 913–936 of 7,141 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pain treatment Clear all
Recruiting Not applicable Interventional

Stepped-Care Intervention of Music and Imagery to Assess Relief (SCIMITAR) Trial

NCT07217821
View directory record Official record
Conditions
Chronic Musculoskeletal Pain, Veterans, Music Therapy
Interventions
Stepped-care
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Assessment of Abuse Potential of Cebranopadol in Humans

NCT05256108
View directory record Official record
Conditions
Human Abuse Potential
Interventions
Oxycodone 40 mg, Tramadol 600 mg, Placebo, Cebranopadol 600 µg, Cebranopadol 1000 µg
Drug
Lead sponsor
Tris Pharma, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 27, 2022 · Synced Oct 22, 2026, 8:09 PM EDT
Recruiting Phase 4 Interventional

Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease

NCT06665997
View directory record Official record
Conditions
Sickle Cell Disease (SCD), Vaso-Occlusive Pain Episode in Sickle Cell Disease
Interventions
Depot medroxyprogesterone acetate (DMPA)
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Atlanta, Georgia • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 22, 2026, 8:09 PM EDT
Not yet recruiting Not applicable Interventional

Online Pain Education for Crohn's Disease and Ulcerative Colitis

NCT07671313
View directory record Official record
Conditions
Crohn's Disease, Ulcerative Colitis (UC), Inflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis)
Interventions
Empowered Relief, Living Better with Chronic Pain
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Not applicable Interventional

Psychosocial Pain Management During Addictions Treatment to Improve Outcomes

NCT01372267
View directory record Official record
Conditions
Pain
Interventions
Psychoeducation for substance abuse, CBT for pain in Substance abuse
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
510 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Waterford, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Not applicable Interventional

Physical Therapy on Non-structural Medial Elbow Pain

NCT05537636
View directory record Official record
Conditions
Elbow Injuries and Disorders, Neuritis, Ulnar, Neuritis, Brachial, Neuritis; Nerve Root, Neuritis Median Nerve
Interventions
Rehabiltiation using exercise and manual therapy
Other
Lead sponsor
Timothy Uhl
Other
Eligibility
15 Years to 50 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 22, 2023 · Synced Oct 22, 2026, 8:09 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Phase 3 Study of Local Administration of SKY0402 for Postoperative Analgesia in Subject Undergoing Breast Augmentation

NCT00813111
View directory record Official record
Conditions
Pain
Interventions
SKY0402, Bupivacaine HCl
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
15
States / cities
Birmingham, Alabama • Mobile, Alabama • La Jolla, California + 10 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2014 · Synced Oct 22, 2026, 8:09 PM EDT
Recruiting Not applicable Interventional

Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia

NCT07644221
View directory record Official record
Conditions
Fibromyalgia (FM)
Interventions
Primary Motor Cortex Stimulation, Occipital Lobe Stimulation
Device
Lead sponsor
Pulkit Grover
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Combined Effect of TENS and TaVNS on Pressure and Heat Pain Thresholds in Pain-Free Subjects

NCT06361381
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Active Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS), Placebo Transcutaneous Auricular Vagus Nerve Stimulation (TaVNS), Transcutaneous Electrical Nerve Stimulation
Device
Lead sponsor
University of Hartford
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 22, 2026, 8:09 PM EDT
Terminated Not applicable Interventional

Manipulation Under Anesthesia Versus Arthroscopic Capsular Release in the Treatment of Adhesive Capsulitis

NCT01961219
View directory record Official record
Conditions
Adhesive Capsulitis of the Shoulder
Interventions
Manipulation Under Anesthesia, Arthroscopic capsular release
Procedure
Lead sponsor
Akin Cil
Other
Eligibility
18 Years to 75 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Investigation of ReNu™ Knee Injection in Patients With Osteoarthritis

NCT02318511
View directory record Official record
Conditions
Osteoarthritis
Interventions
Knee injection, ReNu amniotic allograft, placebo saline, Hyaluronic Acid
Procedure · Other · Device
Lead sponsor
NuTech Medical, Inc
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
12
States / cities
Birmingham, Alabama • Los Angeles, California • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Phase 3 Interventional Results available

A Single-arm Study to Evaluate Safety and Effectiveness of VX-548 for Acute Pain

NCT05661734
View directory record Official record
Conditions
Pain
Interventions
Suzetrigine
Drug
Lead sponsor
Vertex Pharmaceuticals Incorporated
Industry
Eligibility
18 Years to 80 Years
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
14
States / cities
Anaheim, California • Bakersfield, California • Miami, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 22, 2026, 8:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Labor Pain and Postpartum Behavioral Health Outcomes Study

NCT02692404
View directory record Official record
Conditions
Depression, Postpartum, Pregnancy, Child Development, Pain, Labor Pain
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 22, 2026, 8:09 PM EDT
Terminated Phase 4 Interventional Results available

Needle-free Delivery of Intralesional Triamcinolone for Pediatric Alopecia Areata

NCT05278858
View directory record Official record
Conditions
Alopecia Areata
Interventions
MedJet Device with intralesional triamcinolone
Combination Product
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
6 Years to 17 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Not applicable Interventional Results available

A Pilot Study Investigating the nCAP Signal Relief Patch in Subjects Undergoing Primary Hip or Knee Replacement Surgery

NCT05252858
View directory record Official record
Conditions
Opioid Use, Pain, Post Operative
Interventions
nCAP Signal Relief Patch, Standard of Care
Device · Other
Lead sponsor
Jacques E. Chelly
Other
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Not applicable Interventional Results available

Lidocaine and Prevention of Chronic Pain

NCT01619852
View directory record Official record
Conditions
Surgery
Interventions
.9 normal saline placebo, Group L (lidocaine)
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 27, 2019 · Synced Oct 22, 2026, 8:09 PM EDT
Terminated Phase 4 Interventional

Liposomal Bupivacaine Infiltration vs Continuous Perineural Ropivacaine Infusion for Post-operative Pain After Total Shoulder Arthroplasty

NCT02787226
View directory record Official record
Conditions
Postoperative Pain, Shoulder Arthritis
Interventions
Liposomal Bupivacaine Infiltration, Continuous Perineural Ropivicaine Infusion
Drug
Lead sponsor
Eric Shepard
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 9, 2018 · Synced Oct 22, 2026, 8:09 PM EDT
Completed No phase listed Observational

Sleep/Wake Protocol Implementation to Improve Sleep Quality in the ICU

NCT03313115
View directory record Official record
Conditions
Sleep Deprivation, Delirium
Interventions
Sleep/Wake Protocol
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
685 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Oct 22, 2026, 8:09 PM EDT
Recruiting Phase 1Phase 2 Interventional

Medical Herbs Inhibit Inflammation Directing T Cells to Kill the COVID-19 Virus (COVID)

NCT04790240
View directory record Official record
Conditions
Covid19 Virus Infection
Interventions
Inflammation (I), Inflammation (II), Inflammation (III), Standard of care
Dietary Supplement · Drug
Lead sponsor
All Natural Medicine Clinic, LLC
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Phase 1 Interventional

Efficacy of Music Therapy Protocols for Burn Debridement

NCT00822497
View directory record Official record
Conditions
Pain Management
Interventions
Music-Based Imagery (MBI), Music Alternate Engagement (MAE)
Behavioral
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
7 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 23, 2010 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Not applicable Interventional

Comparing the Effectiveness of 2 Diets for Patients With Irritable Bowel Syndrome

NCT01624610
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Dietary intervention
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 31, 2016 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Not applicable Interventional

The Confounding Burden of Psychological Impairments in Cervical Spine Surgery

NCT03183713
View directory record Official record
Conditions
Cervical Spine Disease, Psychological Impairment
Interventions
Cognitive Behavioral Therapy, Sham Therapy
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pain Control in Hip Arthroscopy: Comparing Lumbar Plexus Versus Peri-capsular Injection

NCT03244631
View directory record Official record
Conditions
Nerve Block, Hip Arthroscopy
Interventions
Lumbar Plexus BLock, Pericapsular injection
Procedure
Lead sponsor
Washington Orthopaedics and Sports Medicine
Other
Eligibility
25 Years to 60 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Chevy Chase, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Oct 22, 2026, 8:09 PM EDT
Completed Phase 2 Interventional Results available

Study of Diclofenac Capsules to Treat Dental Pain

NCT00985439
View directory record Official record
Conditions
Dental Pain
Interventions
Diclofenac Test (lower dose), Diclofenac Test (upper dose), Celecoxib 400 mg, Placebo
Drug
Lead sponsor
Iroko Pharmaceuticals, LLC
Industry
Eligibility
18 Years to 50 Years
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2012 · Synced Oct 22, 2026, 8:09 PM EDT