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ClinicalTrials.gov public records Last synced Oct 19, 2026, 4:21 PM EDT

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Showing 169–192 of 7,138 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pain treatment Clear all
Terminated Not applicable Interventional

Wearable Therapeutic Ultrasound Study for Knee Osteoarthritis

NCT01993693
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Ultrasonic Diathermy Device, Sham Ultrasonic Diathermy Device
Device
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
35 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
East Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2015 · Synced Oct 19, 2026, 4:21 PM EDT
Completed Phase 3 Interventional

Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone

NCT00003884
View directory record Official record
Conditions
Hypercalcemia of Malignancy, Lung Cancer, Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
zoledronic acid, quality-of-life assessment
Drug · Procedure
Lead sponsor
Novartis
Industry
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2001
U.S. locations
55
States / cities
Birmingham, Alabama • Springdale, Arkansas • Gilroy, California + 48 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2013 · Synced Oct 19, 2026, 4:21 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Ultra-low Dose Oral Ketamine for Chronic Pain in the Primary Care Setting

NCT02303847
View directory record Official record
Conditions
Chronic Pain
Interventions
Ketamine
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Lacey, Washington
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Oct 19, 2026, 4:21 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality for Phantom Limb Pain

NCT02784548
View directory record Official record
Conditions
Phantom Limb Pain
Interventions
Virtual Reality
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2019 · Synced Oct 19, 2026, 4:21 PM EDT
Enrolling by invitation Not applicable Interventional

Comparing Two Moral Injury Treatments

NCT07710521
View directory record Official record
Conditions
Moral Injury
Interventions
Acceptance and Commitment Therapy for Moral Injury (ACT-MI), Present Centered Therapy for Moral Injury (PCT-MI)
Behavioral
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 89 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 19, 2026, 4:21 PM EDT
Completed Not applicable Interventional

Transcutaneous VNS to Treat Pediatric IBD

NCT03863704
View directory record Official record
Conditions
Crohn Disease, Ulcerative Colitis
Interventions
Transcutaneous Electrical Nerve Stimulation (TENS)
Device
Lead sponsor
Northwell Health
Other
Eligibility
10 Years to 21 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 19, 2026, 4:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trigger Point Dry Needling With and Without Electrical Stimulation in Healthy Subjects

NCT07384247
View directory record Official record
Conditions
People With Identified Painful Trigger Points (Tp) Within the Soleus and Gastrocnemius Muscles Complex, Healthy Subjects or Volunteers
Interventions
Dry needling with electrical stimulation, Dry needling, Electrical stimulation, Sham
Procedure
Lead sponsor
University of Rhode Island
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Kingston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 19, 2026, 4:21 PM EDT
Not listed Not applicable Interventional

E-STIM Trial: Comparing the Efficacy of the Empi Select TENS to a Control for the Treatment of Chronic Lower Back Pain

NCT00709748
View directory record Official record
Conditions
Lower Back Pain
Interventions
Empi Select TENS Device, Placebo
Device
Lead sponsor
Empi, A DJO Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
8
States / cities
Fair Oaks, California • Pensacola, Florida • St. Petersburg, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2008 · Synced Oct 19, 2026, 4:21 PM EDT
Not yet recruiting No phase listed Observational

Outcomes Registry After Ketamine Infusions for Chronic Pain: A Longitudinal Evaluation

NCT07648771
View directory record Official record
Conditions
Chronic Pain, Ketamine
Interventions
Ketamine (Ketalar)
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2034
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 19, 2026, 4:21 PM EDT
Completed Phase 3 Interventional Results available

4-drug Nerve Block Versus Plain Local Anesthetic for Knee and Hip Arthroplasty Analgesia in Veterans

NCT02891798
View directory record Official record
Conditions
Pain
Interventions
Bupivacaine + CBD (clonidine, buprenorphine, dexamethasone), Bupivacaine Only (control arm)
Drug
Lead sponsor
Brian Williams
Federal
Eligibility
18 Years to 85 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 14, 2022 · Synced Oct 19, 2026, 4:21 PM EDT
Terminated Phase 2 Interventional Results available

A Clinical Study To Investigate The Effectiveness And Safety Of Tanezumab In Treating Pain Associated With Endometriosis

NCT00784693
View directory record Official record
Conditions
Endometriosis
Interventions
Tanezumab, Placebo
Biological · Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 49 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
30
States / cities
Mobile, Alabama • Tucson, Arizona • San Diego, California + 20 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2021 · Synced Oct 19, 2026, 4:21 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Aspen™ Ultrasound System and Aspen Rehabilitation Technique in the Treatment of Capsular Contracture

NCT02840084
View directory record Official record
Conditions
Capsular Contracture of Breast, Grade III
Interventions
Aspen(TM) Ultrasound System
Device
Lead sponsor
Nina Naidu
Individual
Eligibility
22 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 15, 2021 · Synced Oct 19, 2026, 4:21 PM EDT
Completed No phase listed Interventional Results available

Evaluation of Erchonia PPL Laser as a Pretreatment Adjunct to Enhance Standard Erchonia Red Laser for the Relief of Pain

NCT07121933
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Erchonia® PPL blue laser therapy, followed sequentially with the standard Erchonia red laser therapy
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
22 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
West Covina, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 19, 2026, 4:21 PM EDT
Completed Not applicable Interventional Results available

Combined Application of Electrical Stimulation and Volitional Contractions for Muscle Strengthening and Knee Pain Inhibition (Seated Study)

NCT02802878
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Hybrid Training using Electrodes and Joint Motion Sensors, Isokinetic Training with Isokinetic Dynamometer
Device
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
40 Years to 85 Years · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 18, 2018 · Synced Oct 19, 2026, 4:21 PM EDT
Terminated Phase 4 Interventional Results available

Two Dose Epidural Morphine for Post-cesarean Analgesia

NCT01844206
View directory record Official record
Conditions
Pain, Morphine Adverse Reaction
Interventions
Epidural Morphine, Epidural Saline
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 23, 2015 · Synced Oct 19, 2026, 4:21 PM EDT
Withdrawn No phase listed Observational

Post-Breast Procedure Pain Syndrome Study

NCT01114984
View directory record Official record
Conditions
Breast, Mastectomy, Segmental
Interventions
Not listed
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2015 · Synced Oct 19, 2026, 4:21 PM EDT
Withdrawn Not applicable Interventional

Mindfulness Meditation and Bariatric Surgery

NCT04167852
View directory record Official record
Conditions
Opioid Use, Bariatric Surgery Candidate, Pain, Postoperative
Interventions
Daily text message, Mindfulness intervention
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 23, 2021 · Synced Oct 19, 2026, 4:21 PM EDT
Withdrawn Phase 2Phase 3 Interventional

Functional Microarray Augmentation of Skin Treatment With Lidocaine

NCT01145326
View directory record Official record
Conditions
Pain Perception, Phlebotomy
Interventions
4% lidocaine gel application with sham microneedle device, Microneedle-facilitated lidocaine application
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 16, 2017 · Synced Oct 19, 2026, 4:21 PM EDT
Completed Phase 2 Interventional

BG00010 (Neublastin) Phase 2 Multiple Dose Adaptive Design in Participants With Painful Lumbar Radiculopathy

NCT01873404
View directory record Official record
Conditions
Painful Lumbar Radiculopathy, Sciatica, Radiculopathy
Interventions
BG00010, Placebo
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years and older
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
25
States / cities
Phoenix, Arizona • Fresno, California • Lomita, California + 22 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2015 · Synced Oct 19, 2026, 4:21 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Veteran Affairs Osteoarthritis Knee Study

NCT04698733
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
BEST™ HVPC microcurrent electrical stimulation Pro-Sport Ultra® device
Device
Lead sponsor
Avazzia, Inc
Industry
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2021 · Synced Oct 19, 2026, 4:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hand & Foot Nocturnal Enuresis TENS Study

NCT02747849
View directory record Official record
Conditions
Bedwetting
Interventions
TENS
Device
Lead sponsor
Rajeev Chaudhry
Other
Eligibility
5 Years to 18 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 21, 2023 · Synced Oct 19, 2026, 4:21 PM EDT
Completed Phase 3 Interventional Results available

Tapentadol IR vs Oxycodone IR vs Placebo in Acute Pain From Vertebral Compression Fracture Associated With Osteoporosis

NCT00771758
View directory record Official record
Conditions
Back Pain
Interventions
oxycodone IR, placebo, tapentadol IR
Drug
Lead sponsor
Ortho-McNeil Janssen Scientific Affairs, LLC
Industry
Eligibility
50 Years to 85 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
37
States / cities
Haleyville, Alabama • Tallassee, Alabama • Peoria, Arizona + 34 more
Source: ClinicalTrials.gov public record
Updated May 9, 2014 · Synced Oct 19, 2026, 4:21 PM EDT
Not yet recruiting Not applicable Interventional

E-MOHS Trial of TENS and Vibration During Local Anesthesia

NCT07852455
View directory record Official record
Conditions
Pain, Procedural Pain, Local Anesthesia, Mohs Surgery, Skin Cancer
Interventions
Active Vibration:TENS, Sham TENS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
3
States / cities
Maple Grove, Minnesota • Minneapolis, Minnesota • Wyoming, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 19, 2026, 4:21 PM EDT
Completed Phase 4 Interventional Results available

A Novel Analgesia Technique for ACL Reconstruction

NCT03292926
View directory record Official record
Conditions
Anterior Cruciate Ligament Injury
Interventions
Bupivacaine, Ultrasound, Dexamethasone
Drug · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
13 Years to 80 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 19, 2026, 4:21 PM EDT