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Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Paired brain and nerve stimulation Clear all
Completed Not applicable Interventional

PCMS Task After Moderate-to-severe Stroke

NCT05736653
View directory record Official record
Conditions
Stroke
Interventions
Task-specific PCMS, Task-specific sham-PCMS, PCMS-rest
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 26, 2026, 2:05 AM EDT
Recruiting Not applicable Interventional

Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia

NCT07225582
View directory record Official record
Conditions
Spinal Cord Injury Cervical, Spinal Cord Injuries (Complete and Incomplete)
Interventions
Brain Computer Interface (BCI) - Functional Electrical Stimulation (FES) system
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
22 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 26, 2026, 2:05 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Memory & Conditioning Under Anesthesia

NCT04062123
View directory record Official record
Conditions
Anesthesia, Pain
Interventions
Dexmedetomidine, Propofol, Fentanyl, Peripheral Nerve Stimulation, Placebo
Drug · Device
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years to 39 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Sep 26, 2026, 2:05 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cervical Spinal Cord Associative Plasticity

NCT07539025
View directory record Official record
Conditions
Cervical Spinal Cord Plasticity
Interventions
SCAP, MagPro X100, Digitimer DS8R, Paired non-associative stimulation
Other · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 26, 2026, 2:05 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Brain State-dependent PCMS in Chronic Stroke

NCT04830163
View directory record Official record
Conditions
Stroke
Interventions
Brain state-dependent paired corticomotoneuronal stimulation (PCMS)
Combination Product
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 26, 2026, 2:05 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Noninvasive Brain Stimulation to Evaluate Neural Plasticity After Stroke

NCT02465034
View directory record Official record
Conditions
Cerebrovascular Stroke
Interventions
Transcranial Magnetic Stimulation, Traditional Paired Associative Stimulation, Median Nerve Stimulation, Corticocortical Paired Associative Stimulation, Sham Paired Associative Stimulation
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 85 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 25, 2021 · Synced Sep 26, 2026, 2:05 AM EDT
Recruiting Not applicable Interventional

Trigeminal Nerve Stimulation for Children With Prenatal Alcohol Exposure

NCT06847165
View directory record Official record
Conditions
Fetal Alcohol Spectrum Disorders, Attention Deficit Hyperactivity Disorder
Interventions
Trigeminal Nerve Stimulation (TNS)
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
8 Years to 12 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 26, 2026, 2:05 AM EDT
Recruiting Not applicable Interventional

Spinal Cord Associative Plasticity in Cerebral Palsy

NCT07607665
View directory record Official record
Conditions
Hemiplegic Cerebral Palsy
Interventions
Paired brain and nerve stimulation
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 26, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

VNS-induced Corticospinal Plasticity

NCT04088565
View directory record Official record
Conditions
Stroke
Interventions
Paired-Associative Stimulation (PAS), Vagus Nerve Stimulation (VNS), Sham Stimulation
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 75 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced Sep 26, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Physiological Investigations of Movement Disorders

NCT01019343
View directory record Official record
Conditions
Parkinson's Disease, Tourette's Syndrome, Tic Disorders, Dystonia, Movement Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Eye-tracking Device, Pulsed vibrator, Gait Trainer Treadmill (GTT), Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA, iMobility, QMAT, Treadmill Test, Arm Intellistretch Device, Transcranial Sonography (TCS), Behavioral tasks, TMS single/paired pulse, MEG, EEG, MRI techniques, Peripheral Nerve Stimulation, EMG, Trancutaneous spinal direct current stimulation (tsDCS)
Procedure · Device · Other + 1 more
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
1,273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Sep 26, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Brain and Nerve Stimulation for Hand Muscles in Spinal Cord Injury and ALS

NCT02469675
View directory record Official record
Conditions
Spinal Cord Injury (SCI), Amyotrophic Lateral Sclerosis (ALS)
Interventions
Transcranial magnetic stimulation, Median nerve stimulation, Cervical transcutaneous stimulation
Device
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
21 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2018 · Synced Sep 26, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Aerobic Exercise and Neuroplasticity in Depression

NCT02839837
View directory record Official record
Conditions
Depression, Depressive Disorder
Interventions
Aerobic Exercise, Paired Associative Stimulation
Behavioral · Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 50 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Sep 26, 2026, 2:05 AM EDT
Completed Early Phase 1 Interventional Results available

taVNS Paired With Bottle Feeding in Infants Failing Oral Feeds

NCT04643808
View directory record Official record
Conditions
Poor Feeding, Infant Development, Vagus Nerve Stimulation
Interventions
transcutaneous auricular vagus nerve stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
3 Weeks to 5 Months
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 29, 2023 · Synced Sep 26, 2026, 2:05 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Paired Stimulation Plasticity for Motor Recovery in Humans With and Without Spinal Cord Injury

NCT07814313
View directory record Official record
Conditions
Healthy Control, Spinal Cord Injury
Interventions
CST PAS, RST PAS, sham PAS
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
19 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 26, 2026, 2:05 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Assessing the Effects of Hormones on Noninvasive Transcranial Stimulation

NCT07635017
View directory record Official record
Conditions
Cortical Excitability, Healthy, TMS, Menstrual Cycle, Menopause
Interventions
Transcranial Electrical Stimulation, Transcranial Magnetic Stimulation, TES + TMS
Device
Lead sponsor
Carnegie Mellon University
Other
Eligibility
18 Years to 40 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 26, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing STDP After Spinal Cord Injury

NCT02701777
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
STDP, Training, Sham STDP, Multisite-STDP
Other · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 85 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Sep 26, 2026, 2:05 AM EDT