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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Paravertebral Block Clear all
Completed Phase 3 Interventional Results available

Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data

NCT04606264
View directory record Official record
Conditions
Perioperative Optimization
Interventions
Neuraxial Analgesia, Regional Block 1: Paravertebral, Perphenazine, Aprepitant, Dimenhydrinate, Ondansetron 4 MG, Dexamethasone, Regional Block 2: QL1
Drug
Lead sponsor
Jennifer Holder-Murray
Other
Eligibility
18 Years and older
Enrollment
3,395 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 23, 2026, 10:35 PM EDT
Completed Phase 4 Interventional Results available

Pectoralis Block vs Paravertebral Nerve Blocks for Breast Surgery

NCT04742309
View directory record Official record
Conditions
Breast Surgery
Interventions
Pecs-2 block (single injection), Paravertebral block (single injection)
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 25, 2024 · Synced Sep 23, 2026, 10:35 PM EDT
Not listed Not applicable Interventional

Paravertebral Block for Percutaneous Nephrolithotomy

NCT01480102
View directory record Official record
Conditions
Post Operative Pain
Interventions
Group A-Paravertebral block, Group B- No block
Drug · Other
Lead sponsor
Loyola University
Other
Eligibility
18 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Sep 23, 2026, 10:35 PM EDT
Terminated Early Phase 1 Interventional

PVB vs Ketamine/Lidocaine in Rib Fracture Patients

NCT04413799
View directory record Official record
Conditions
Rib Fractures, Rib Trauma, Rib Fracture Multiple, Pain, Acute
Interventions
lidocaine, ketamine intravenous infusion, paravertebral block with ropivicaine
Combination Product · Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2025 · Synced Sep 23, 2026, 10:35 PM EDT
Terminated Not applicable Interventional Results available

TEA vs. PVB vs. PCA in Liver Resection Surgery

NCT02192879
View directory record Official record
Conditions
Pain Management Strategies in Liver Resection Surgery
Interventions
thoracic epidural, continuous paravertebral catheter, Patient-Controlled Analgesia
Device · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 23, 2016 · Synced Sep 23, 2026, 10:35 PM EDT
Not listed Not applicable Interventional

Ultrasound vs. Predetermined Distance Techniques for Paravertebral Nerve Block in Patients Having Breast Surgery

NCT01217593
View directory record Official record
Conditions
Mastectomy, Breast Neoplasms
Interventions
ultrasound, predetermined distance
Procedure
Lead sponsor
Ochsner Health System
Other
Eligibility
25 Years to 85 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 20, 2014 · Synced Sep 23, 2026, 10:35 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Continuous Erector Spinae Block Versus Continuous Paravertebral Block

NCT03768440
View directory record Official record
Conditions
Pain, Postoperative
Interventions
continuous erector spinae block (ESB), continuous paravertebral block (PVB), Ropivacaine
Procedure · Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Month to 12 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 23, 2026, 10:35 PM EDT
Terminated Not applicable Interventional

Chronic Post Breast Surgery Pain

NCT00847067
View directory record Official record
Conditions
Breast Cancer
Interventions
Paravertebral block, Sham injections
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2010 · Synced Sep 23, 2026, 10:35 PM EDT
Enrolling by invitation Phase 4 Interventional

A Study of Paravertebral Block in Thoracic Outlet Syndrome

NCT05544721
View directory record Official record
Conditions
Thoracic Outlet Syndrome
Interventions
Ropivacaine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 23, 2026, 10:35 PM EDT
Completed Phase 3 Interventional

Comparison of Paravertebral Block With General Anesthesia in Patients Undergoing Breast Cancer Surgery

NCT00645138
View directory record Official record
Conditions
Breast Cancer
Interventions
Paravertebral Block, General Anesthesia
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2011 · Synced Sep 23, 2026, 10:35 PM EDT
Completed Phase 4 Interventional Results available

Serratus Plane Versus Paravertebral Nerve Blocks for Breast Surgery

NCT03860974
View directory record Official record
Conditions
Breast Surgery
Interventions
Serratus Plane block (single injection), Paravertebral block (single injection)
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 20, 2022 · Synced Sep 23, 2026, 10:35 PM EDT
Terminated Not applicable Interventional

Study of the Effect of Regional Nerve Blocks on Pain and Inflammation After Video Assisted Thorascopic Lung Surgery

NCT00639795
View directory record Official record
Conditions
Pain
Interventions
Thoracic Paravertebral Nerve Block
Procedure
Lead sponsor
Memorial Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Johnstown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 2, 2013 · Synced Sep 23, 2026, 10:35 PM EDT
Completed Phase 2 Interventional Results available

Video-assisted Thoracoscopic Surgery - Exparel Study

NCT04864210
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Liposomal bupivacaine, Bupivacaine
Drug
Lead sponsor
Nada Sadek
Other
Eligibility
18 Years to 80 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 23, 2026, 10:35 PM EDT
Completed Not applicable Interventional

Paravertebral Blocks: Pilot Study to Compare Nerve Stimulation vs. Anatomic Landmarks in Inguinal Hernia Repair

NCT00587704
View directory record Official record
Conditions
Inguinal Hernia
Interventions
PVB using nerve stimulation, PVB using anatomic landmarks
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 22, 2010 · Synced Sep 23, 2026, 10:35 PM EDT
Completed No phase listed Observational

Nuss Procedure: Clinical Options in Pediatric Pain Management?

NCT02009267
View directory record Official record
Conditions
Pectus Excavatum
Interventions
Patient controlled analgesia, Continuous thoracic epidural infusions, Continuous paravertebral blockade
Device · Procedure
Lead sponsor
Ralph Beltran
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Sep 23, 2026, 10:35 PM EDT
Completed Not applicable Interventional Results available

A Pain Study Comparing Two Commonly Used Medications to Treat Pain After Bowel Surgery

NCT02849678
View directory record Official record
Conditions
Postoperative Pain
Interventions
Ropivacaine, Lidocaine
Drug
Lead sponsor
Jacques E. Chelly
Other
Eligibility
18 Years to 80 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Sep 23, 2026, 10:35 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Paravertebral Versus Pectoralis Block for Post Mastectomy Pain

NCT03656679
View directory record Official record
Conditions
Pain, Postoperative, Post-Mastectomy Chronic Pain Syndrome, Opioid Use
Interventions
Pectoralis Blockade (PECs), Paravertebral Blockade
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 2, 2021 · Synced Sep 23, 2026, 10:35 PM EDT
Terminated Phase 4 Interventional Results available

Paravertebral Block vs no Block in Open Pancreaticoduodenectomy

NCT05820997
View directory record Official record
Conditions
Pancreaticoduodenectomy
Interventions
Ropivacaine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Sep 23, 2026, 10:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of US-Guided Paravertebral and Proximal Intercostal Nerve Blocks

NCT02911168
View directory record Official record
Conditions
Pain
Interventions
Proximal Intercostal Block, Paravertebral Block
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Sep 23, 2026, 10:35 PM EDT
Terminated Phase 3 Interventional Results available

Pre-op Paravertebral Blocks to Decrease Post-op Pain Following Mastectomy With Immediate Tissue Expander (TE) Reconstruction

NCT02161705
View directory record Official record
Conditions
Postoperative Pain, Postoperative Nausea and Vomiting, Quality of Life
Interventions
Ropivacaine, Saline
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 15, 2020 · Synced Sep 23, 2026, 10:35 PM EDT
Completed Phase 3 Interventional Results available

Evaluate the Use of Paravertebral Block in Reconstructive Breast Surgery

NCT00542542
View directory record Official record
Conditions
Breast Cancer
Interventions
Paravertebral Block, Propofol, Fentanyl, Ropivacaine, Midazolam
Procedure · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 12, 2015 · Synced Sep 23, 2026, 10:35 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Enhanced Recovery Strategies in Elective Breast Surgery

NCT03187080
View directory record Official record
Conditions
Pain, Acute, Nausea, Vomiting, Postoperative, Opioid Use, Satisfaction
Interventions
Paravertebral block procedure using either local anesthetic (0.25% bupivacaine) or sterile saline, Enhanced recovery after breast surgery (ERABS) strategies, Sham paravertebral block using saline, Paravertebral block using local anesthetic
Procedure · Other · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Sep 23, 2026, 10:35 PM EDT
Completed Phase 3 Interventional Results available

Comparison of Three Different Pain Blocks for Subjects Undergoing VATS (Video Assisted Thoracoscopic Surgery) Procedure.

NCT03151434
View directory record Official record
Conditions
Video Assisted Thoracoscopic Surgery, Pain, Postoperative, Pain, Acute
Interventions
US Guided Single Shot Paravertebral Block (0.2% ropivicaine infusion), US Guided Paravertebral Catheter (0.2% ropivicaine bolus), Thoracic Epidural (0.125% bupivicaine/hydromorphone)
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Sep 23, 2026, 10:35 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Quadratus Lumborum vs Erector Spinae Supplementary Blocks With Lumbar Plexus Blocks for Hip PAO

NCT04481451
View directory record Official record
Conditions
Pain, Postoperative, Regional Anesthesia, Hip Dysplasia
Interventions
Erector spinae block with ropivacaine 0.2%, Quadratus lumborum block with ropivacaine 0.2%, Ropivacaine
Procedure · Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
15 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Sep 23, 2026, 10:35 PM EDT