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Showing 1–24 of 61 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Parkinson's Application Clear all
Completed Phase 4 Interventional Results available

Study to Evaluate the Efficacy of Rotigotine on Parkinson's Disease-Associated Pain

NCT01744496
View directory record Official record
Conditions
Advanced Idiopathic Parkinson's Disease
Interventions
Rotigotine, Placebo
Drug
Lead sponsor
UCB BIOSCIENCES GmbH
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
10
States / cities
Gilbert, Arizona • Sunnyvale, California • Tampa, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Sep 25, 2026, 9:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Novel Measurement Concept to Objectively Quantify Severity of Vocal and Speech Related Symptoms Associated With Parkinson's Disease

NCT05421832
View directory record Official record
Conditions
Parkinson Disease
Interventions
Digital Speech Application
Device
Lead sponsor
Northwestern University
Other
Eligibility
30 Years and older
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Sep 25, 2026, 9:05 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Mobile Application for Telerehabilitation in Parkinson's Disease

NCT03459586
View directory record Official record
Conditions
Parkinson Disease
Interventions
9zest app facilitated exercise
Other
Lead sponsor
9zest. Inc.
Industry
Eligibility
40 Years to 75 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Mar 8, 2018 · Synced Sep 25, 2026, 9:05 PM EDT
Not listed Phase 3 Interventional

Study of the Application of Magnetic Fields for the Treatment of Parkinson's Disease

NCT00863226
View directory record Official record
Conditions
Parkinson's Disease, Quality of Life
Interventions
Resonator Device
Device
Lead sponsor
pico-tesla Magnetic Therapies, LLC
Industry
Eligibility
30 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
6
States / cities
Aurora, Colorado • Denver, Colorado • Englewood, Colorado + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2011 · Synced Sep 25, 2026, 9:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biomarkers in Neural Disorders

NCT02761707
View directory record Official record
Conditions
Parkinson's Disease, Alzheimer's Disease, Progressive Supranuclear Palsy, Essential Tremor, Multiple System Atrophy, Drug Induced Parkinson's Disease, Diffuse Lewy Body Disease, Myasthenia Gravis, Spinal Cord Injuries
Interventions
Electrical Brainstem Responses, Olfactory Tests, Visual Deprivation, Peripheral Nerve Stimulation
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Sep 25, 2026, 9:05 PM EDT
Completed Phase 3 Interventional Results available

Trial to Assess Parkinson's Disease (PD) Symptom Control to Four Doses of Rotigotine in a Transdermal Patch

NCT00522379
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Rotigotine, Placebo
Drug · Other
Lead sponsor
UCB Pharma
Industry
Eligibility
30 Years and older
Enrollment
514 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
62
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Gilbert, Arizona + 59 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2014 · Synced Sep 25, 2026, 9:05 PM EDT
Completed Phase 2 Interventional

Treatment of Parkinson's Disease With a Transdermal Skin Patch

NCT00001931
View directory record Official record
Conditions
Parkinson Disease
Interventions
N-0923
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 25, 2026, 9:05 PM EDT
Suspended No phase listed Observational Accepts healthy volunteers

Sensory Filtering in the Human Basal Ganglia as a Mechanism of Parkinson's Disease

NCT05482126
View directory record Official record
Conditions
Parkinson Disease
Interventions
Intraoperative Behavioral Testing, Behavioral Testing
Diagnostic Test
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Sep 25, 2026, 9:05 PM EDT
Completed Not applicable Interventional

Blood Flow Restriction and Exercise in Parkinson's Disease

NCT07221994
View directory record Official record
Conditions
Parkinson' Disease
Interventions
Blood flow restriction (BFR) and aerobic exercise via recumbent stepping (Nu-Step)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 25, 2026, 9:05 PM EDT
Not listed Not applicable Interventional

Motivational Interviewing and Physical Activity Change in Parkinson's Disease

NCT03329833
View directory record Official record
Conditions
Parkinson Disease
Interventions
Motivational Interviewing, Web-based application
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Sep 25, 2026, 9:05 PM EDT
Terminated Phase 3 Interventional Results available

Effect of Rotigotine on Motor Symptoms in Patients With Advanced Parkinson's Disease (PD) With Motor Fluctuations and Symptoms of Gastrointestinal Dysfunction

NCT01536015
View directory record Official record
Conditions
Advanced Parkinson's Disease
Interventions
Rotigotine, Placebo
Drug
Lead sponsor
UCB Pharma
Industry
Eligibility
30 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
26
States / cities
Birmingham, Alabama • Gilbert, Arizona • Fountain Valley, California + 23 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2014 · Synced Sep 25, 2026, 9:05 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia

NCT07284290
View directory record Official record
Conditions
Dementia With Lewy Bodies, Parkinson Disease Dementia, Healthy Controls
Interventions
Syn-One skin biopsy, Multi modal MRI, Assessment of dynamic EEG features over 48-hour periods across all study aims, Plasma biomarkers, Galantamine HBr extended-release 8mg capsules (8mg ER).
Procedure · Diagnostic Test · Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
50 Years to 89 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 25, 2026, 9:05 PM EDT
Recruiting Not applicable Interventional

Effects of Osteopathic Manipulative Treatment Protocol on Sleep Quality in Parkinson's Disease Subjects

NCT06671600
View directory record Official record
Conditions
Parkinsons Disease, Sleep
Interventions
Osteopathic Manipulative Treatment, Sham (No Treatment)
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 25, 2026, 9:05 PM EDT
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation for Freezing of Gait

NCT02266004
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Transcranial Direct Current Stimulation (tDCS), locomotor training
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 80 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 29, 2020 · Synced Sep 25, 2026, 9:05 PM EDT
Not listed Not applicable Interventional

Augmenting Treatment Effects of Voice Therapy in Parkinson Disease

NCT02265315
View directory record Official record
Conditions
Parkinson Disease
Interventions
Transcranial Magnetic Stimulation, Lee Silverman Voice Treatment
Other · Behavioral
Lead sponsor
Le Bonheur Children's Hospital
Other
Eligibility
45 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Sep 25, 2026, 9:05 PM EDT
Recruiting Not applicable Interventional

Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease

NCT07110376
View directory record Official record
Conditions
Parkinson Disease
Interventions
Nighttime Deep Brain Stimulation with Varying Amplitude Settings
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 25, 2026, 9:05 PM EDT
Completed Phase 2 Interventional

Development of Imaging, Clinical and Biochemical Bio-Markers for Parkinson's Disease

NCT00315250
View directory record Official record
Conditions
Parkinson's Disease, Parkinsonian Syndrome
Interventions
[123I]β-CIT
Drug
Lead sponsor
Institute for Neurodegenerative Disorders
Other
Eligibility
22 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 8, 2014 · Synced Sep 25, 2026, 9:05 PM EDT
Completed Not applicable Interventional

ParkinStim: Transcranial Direct Current Stimulation for Parkinson's Disease

NCT02125383
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Active tDCS, Sham tDCS
Procedure
Lead sponsor
Great Lakes NeuroTechnologies Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 9, 2015 · Synced Sep 25, 2026, 9:05 PM EDT
Completed Not applicable Interventional Results available

Investigating Central Neurophysiologic Correlates of Non-Motor Symptoms of Parkinson's Disease

NCT05205772
View directory record Official record
Conditions
Parkinson Disease, Autonomic Dysfunction, Depression
Interventions
transcranial magnetic stimulation
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
50 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Sep 25, 2026, 9:05 PM EDT
Not listed Not applicable Interventional

Effects of Osteopathic Manipulative Treatment (OMT) on Gait Biomechanics in Parkinson's Disease

NCT03616145
View directory record Official record
Conditions
Parkinson Disease
Interventions
Osteopathic Manipulative Treatment (OMT), Light Touch
Procedure · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 25, 2026, 9:05 PM EDT
Completed No phase listed Observational Results available

Airway Protective Mechanisms in PD (R01)

NCT03321019
View directory record Official record
Conditions
Parkinson Disease
Interventions
Capsaicin, Resistive respiratory loads, Event-related evoked potential using electroencephalography (EEG)., Fluoroscopic swallow evaluation
Drug · Device · Other + 1 more
Lead sponsor
University of Florida
Other
Eligibility
45 Years to 85 Years
Enrollment
119 participants
Timeline
2017 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Sep 25, 2026, 9:05 PM EDT
Terminated Not applicable Interventional Results available

Parkinson's Disease Inpatient Clinical Knowledge and Management

NCT03888287
View directory record Official record
Conditions
Parkinson Disease
Interventions
Watch Rx system, Parkinson's Disease Inpatient Clinical Knowledge and Management Program
Device · Other
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
22 Years and older
Enrollment
477 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Sep 25, 2026, 9:05 PM EDT
Completed Phase 4 Interventional Results available

Study to Evaluate the Impact of Using Wearable Devices in Addition to Standard Clinical Practice on Parkinson´s Subject Symptoms Management

NCT03103919
View directory record Official record
Conditions
Parkinson´s Disease
Interventions
Kinesia-ONE™, Kinesia-360™, Rotigotine
Device · Drug
Lead sponsor
UCB Biopharma S.P.R.L.
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
8
States / cities
Fountain Valley, California • Boca Raton, Florida • Winfield, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Sep 25, 2026, 9:05 PM EDT
Completed Phase 2 Interventional

Study of Individuals With Parkinson's Symptoms But in Whom There is Diagnostic Uncertainty

NCT00129675
View directory record Official record
Conditions
Parkinsonian Syndrome
Interventions
[123I]ß CIT
Drug
Lead sponsor
Institute for Neurodegenerative Disorders
Other
Eligibility
21 Years and older
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 15, 2014 · Synced Sep 25, 2026, 9:05 PM EDT