Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 12, 2026, 7:38 PM EDT

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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Conditions
Sickle Cell Disease, Vaso-occlusive Pain Episode in Sickle Cell Disease, Acute Pain
Interventions
Virtual Reality Headset and Hand-Held Controllers, Blindfolding and Noise Cancelling
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Chronic Pain, Chronic Back Pain, Chronic Lower Back Pain (CLBP)
Interventions
Skills-based Virtual Reality Therapy, Distraction-based Virtual Reality Therapy
Device
Lead sponsor
CognifiSense Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boulder, Colorado
Conditions
Anxiety Fear, Pain
Interventions
Take-Pause virtual reality, Passive Distraction
Device
Lead sponsor
Antonios Likourezos
Other
Eligibility
13 Years to 17 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Brooklyn, New York
Not yet recruiting Not applicable Interventional

Virtual Reality for SCD VOC

NCT07674277
Conditions
Sickle Cell Disease
Interventions
Sham 2D Headset Control, Passive Immersive 3D Virtual Reality, Active Immersive Interactive 3D Virtual Reality
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 89 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Multiple Sclerosis, Frailty
Interventions
Multimodal Exercise Group, Waitlist
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
40 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Burns, Wound Care, Pain
Interventions
Virtual Reality, Passive Distraction
Device · Other
Lead sponsor
University of Arkansas
Other
Eligibility
10 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Pain
Interventions
Active Virtual Reality, Passive Virtual Reality
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
8 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers

Water-friendly Virtual Reality and Brief Thermal Pain

NCT04245475
Conditions
Pain, Acute
Interventions
Virtual Reality psychological pain reduction
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Chronic Illness, Hematologic Malignancy, Bone Marrow Transplant Infection, Oncology, Sickle Cell Disease
Interventions
Guided Imagery, Virtual Reality
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
8 Years to 25 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Milwaukee, Wisconsin • Wauwatosa, Wisconsin
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Healthy Children and Virtual Reality Mediation of Simulated Pain

NCT06854991
Conditions
Acute Pain, Experimental Pain in Healthy Human Participants, Children, Adolescents
Interventions
Active VR-PAT, Passive VR-PAT, iPad
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
End Stage Kidney Disease, Depressive Symptoms
Interventions
Joviality(TM), Inert Virtual Reality
Behavioral · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ice Immersion Using Virtual Reality & Augmented Reality

NCT04196686
Conditions
Pain, Neuropathic, Pain, Acute
Interventions
VR/AR, Ice Bath
Device · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Stanford, California
Conditions
Pain, Anxiety, Chronic Rhinosinusitis (CRS), Nasal Obstruction, Nasal Polyp, Eustachian Tube Dysfunction, Dysphonia, Subglottic Stenosis (SGS)
Interventions
Passive virtual reality headset or goggles, Active virtual reality headset or goggles
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Gastroparesis
Interventions
Oculus Go VR headset, Sham Oculus Go VR headset
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Jacsonville, Florida
Completed Not applicable Interventional Accepts healthy volunteers

VR Usage in Non-Invasive Surgical Sub-Specialty Procedures

NCT03464955
Conditions
Stress, Emotional, Stress, Psychological, Behavioral Symptoms
Interventions
Technology Based Distractions
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
2 Years to 18 Years
Enrollment
291 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Pain, Burns
Interventions
VR-based Pain Alleviation Tool (VR-PAT)
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Binge-Eating Disorder
Interventions
Circadian Reset Technology, VR Headset
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Pain, Anxiety
Interventions
Virtual Reality, Standard Procedure Thyroid Biopsy, Standard Procedure PICC Placement
Device · Procedure
Lead sponsor
Temple University
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Pain, Anxiety
Interventions
Oculus Go headset without active intervention, Oculus Go headset with active intervention, Oculus Go headset without immersive virtual reality experience, Oculus Go headset with immersive virtual reality experience
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 99 Years
Enrollment
265 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Stanford, California
Completed Not applicable Interventional Accepts healthy volunteers

Technology-Based Distractions During Minor Procedures

NCT03628989
Conditions
Pain, Anxiety, Procedural Anxiety
Interventions
Use of Virtual Technology
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
Up to 17 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Stroke
Interventions
Home Telerehabilitation using HoVRS
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
40 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Newark, New Jersey