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Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees

NCT05267639
Conditions
Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Above Knee (Injury), Amputation; Traumatic, Leg: Thigh, Between Hip and Knee
Interventions
Power Knee
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Holliston, Massachusetts • Austin, Texas
Conditions
Amputation
Interventions
Hybrid Leg, Prescribed Passive Prosthesis
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 95 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Trans-tibial Amputation
Interventions
Not listed
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Amputation; Traumatic, Hand
Interventions
Point Powered partial hand prosthetic system
Device
Lead sponsor
Point Designs
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Aurora, Colorado • Broomfield, Colorado • Lafayette, Colorado
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Wearing a Powered Ankle-Foot Prosthesis on Amputee Walking

NCT00869947
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Powered ankle-foot prosthesis, No device
Device · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Motorized Prostheses for Lower-limb Amputees

NCT07486063
Conditions
Lower-Limb Amputation
Interventions
Powered and passive lower limb prosthesis and control
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2032
U.S. locations
1
States / cities
Salt Lake City, Utah
Recruiting Not applicable Interventional Accepts healthy volunteers

The Influence of 3D Printed Prostheses on Neural Activation Patterns

NCT04110730
Conditions
Amniotic Band Syndrome, Upper Extremity Deformities, Congenital
Interventions
3D Printed Upper-limb Prosthesis, Home Intervention
Device · Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
3 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Prosthesis User, Lower Limb Amputation Below Knee (Injury)
Interventions
Caesar Foot
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Austin, Texas
Completed Not applicable Interventional Results available

BCI-FES Therapy for Stroke Rehabilitation

NCT04279067
Conditions
Ischemic Stroke, Hemorrhagic Stroke
Interventions
BCI-FES dorsiflexion therapy, Physiotherapy one hour, Physiotherapy two hours
Device · Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 80 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Irvine, California
Conditions
Amputation; Traumatic, Hand, Amputation, Congenital
Interventions
Point Mini
Device
Lead sponsor
Point Designs
Industry
Eligibility
3 Years to 17 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Lafayette, Colorado • Atlanta, Georgia
Not listed Not applicable Interventional Accepts healthy volunteers

Comparing Intact and Residual Amputated Muscle

NCT06182202
Conditions
Amputation
Interventions
Powered Prosthesis
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 64 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Investigation of Motorized Lower-limb Prostheses

NCT07584707
Conditions
Ambulation With the "Take Home" or Passive Prosthesis, Ambulation With the Motorized Prosthesis in the "Off" Configuration, Ambulation With the Motorized Prosthesis in the "Transparent" Condition, Ambulation With the Motorized Prosthesis in the "Powered" Condition
Interventions
Passive prosthesis, Motorized prosthesis
Device
Lead sponsor
Northern Arizona University
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Flagstaff, Arizona
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating Mobility Interventions in the Real World

NCT04275973
Conditions
Lower Limb Amputation, Drop Foot
Interventions
Lower limb prostheses, Orthoses for Drop-foot
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Amputation
Interventions
Fillauer Slope Adaptive Foot, Fillauer Motion Foot SLX
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Upper Limb Amputation at the Hand, Upper Limb Amputation at the Wrist, Amputation, Amputation; Traumatic, Limb
Interventions
Commercially available device, Non FDA registered device
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 95 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Above Knee (Injury), Amputation; Traumatic, Leg: Thigh, Between Hip and Knee
Interventions
Ossur Power Knee, Reboocon Intuy Knee
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Austin, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Design, Prototyping, and Testing of a Robotic Prosthetic Leg

NCT04616378
Conditions
Amputation; Traumatic, Leg, Lower
Interventions
Phase 2 Prescribed Prosthesis, Phase 2 Robotic Prosthetic Leg, Phase 3 No Prosthesis, Phase 3 Robotic Prosthetic Leg, Phase 3 Prescribed Prosthesis
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Loma Linda, California
Conditions
Transtibial Amputation - Unilateral
Interventions
MIT Variable Stiffness Prosthesis v1, MIT Variable Equilibrium Angle Prosthesis v1, MIT Sliding Beam Passive Prosthesis, Ossur Pro-Flex XC, Blatchford Elan Variable-Dampening Prosthesis, Ossur Proprio Variable Angle Prosthesis, MIT Variable Stiffness Prosthesis v2, MIT Variable Equilibrium Angle Prosthesis v2
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Burlington, Massachusetts • Cambridge, Massachusetts
Conditions
Lower Limb Amputation Below Knee (Injury)
Interventions
direct EMG controlled prosthetic ankle, PT guided prosthetic training
Device · Behavioral
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Raleigh, North Carolina
Completed No phase listed Observational Accepts healthy volunteers Results available

Does Walking Performance Improve When Veterans With Leg Amputations Are Given Visual Feedback?

NCT03974945
Conditions
Amputation
Interventions
Passive-elastic prosthetic foot, Powered ankle-foot prosthesis
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 67 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Withdrawn Not applicable Interventional Accepts healthy volunteers

Investigation of Embodiment for Upper Limb Amputees

NCT04578327
Conditions
Amputation
Interventions
Prosthetic hand, Peripheral Nerve Interface
Device · Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Results available

EmPOWERing Active Seniors With Energy

NCT02958553
Conditions
Amputation
Interventions
emPOWER Ankle, Subject's own passive prosthesis
Device
Lead sponsor
Otto Bock Healthcare Products GmbH
Industry
Eligibility
55 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houston, Texas
Conditions
Amputation, Amputation, Traumatic, Amputation of Knee, Amputation; Traumatic, Limb
Interventions
Ottobock CLeg4 + Ottobock foot, SRALAB Hybrid Knee + Polycentric Ankle, SRALAB Hybrid Knee + Passive Ankle, Ottobock CLeg 4 + Polycentric Ankle
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 95 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Vestibular Disorder, Vestibular Ataxia, Vestibular Loss, Bilateral
Interventions
Vestibular prosthesis/implant, Vestibular Implant Stimulation
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts • Columbus, Ohio