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ClinicalTrials.gov public records Last synced Oct 25, 2026, 7:56 AM EDT

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Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Pears Clear all
Completed Phase 2 Interventional

The Health-Promoting Role of Pears in Men and Women With Metabolic Syndrome

NCT02228837
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Pear, Placebo
Dietary Supplement
Lead sponsor
Florida State University
Other
Eligibility
45 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Dec 8, 2016 · Synced Oct 25, 2026, 7:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Activity Levels, Inflammatory Markers, and Overall Wellness.

NCT03619265
View directory record Official record
Conditions
Range of Motion
Interventions
Prickly pear juice, Pear-flavored juice
Dietary Supplement
Lead sponsor
Natural Immune Systems Inc
Other
Eligibility
35 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Klamath Falls, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 12, 2020 · Synced Oct 25, 2026, 7:56 AM EDT
Completed Not applicable Interventional Results available

Promoting Health Through Parent Empowerment and the Activation of Routines (PrO-PEAR)

NCT05020366
View directory record Official record
Conditions
Down Syndrome
Interventions
Promoting Health through Parent Empowerment and the Activation of Routines, Enhanced Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Months and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced Oct 25, 2026, 7:56 AM EDT
Completed Not applicable Interventional Results available

reSET-O RCT (Randomized Controlled Trial)

NCT04129580
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
reSET-O app
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Harrisburg, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Oct 25, 2026, 7:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Nopales (Opuntia Spp.) on Lipoprotein Profile and Oxidative Stress in Moderately Hypercholesterolemic Adults

NCT02209493
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Food supplementation: nopales, Food supplementation: cucumber
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 70 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 7, 2014 · Synced Oct 25, 2026, 7:56 AM EDT
Completed Phase 4 Interventional Results available

Pharmacogenomic Evaluation of Antihypertensive Responses

NCT00246519
View directory record Official record
Conditions
Hypertension
Interventions
Hydrochlorothiazide, Atenolol
Drug
Lead sponsor
University of Florida
Other
Eligibility
17 Years to 65 Years
Enrollment
1,701 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
3
States / cities
Gainesville, Florida • Atlanta, Georgia • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Oct 25, 2026, 7:56 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Adipose Tissue and Polycystic Ovary Syndrome (PCOS)(EIFFEL)

NCT01745471
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Metabolic Diseases, Overweight
Interventions
Not listed
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 25, 2026, 7:56 AM EDT
Completed Phase 2 Interventional Results available

Study of Efficacy of PEAR-004 in Schizophrenia

NCT03751280
View directory record Official record
Conditions
Schizophrenia
Interventions
PEAR-004, Sham
Device
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
6
States / cities
Garden Grove, California • Oakland, California • Torrance, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 25, 2026, 7:56 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

An Examination of Infants' Microbiome, Nutrition, and Development Study.

NCT03229863
View directory record Official record
Conditions
Microbial Colonization, Infant Development
Interventions
Sweet Potatos, Pears
Other
Lead sponsor
University of California, Davis
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 25, 2026, 7:56 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Transcriptional and Epigenetic Program of PCOS Women

NCT04034706
View directory record Official record
Conditions
PCOS
Interventions
DEXA, Magnetic Resonance (MR) Assessment of the Abdomen, MR assessment of Whole Body Fat, Adipose tissue biopsy, Oral glucose tolerance test
Other · Procedure
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Oct 25, 2026, 7:56 AM EDT
Enrolling by invitation Not applicable Interventional

Parent-Educator Action Response

NCT07203014
View directory record Official record
Conditions
Attention Deficit and Disruptive Behavior Disorders
Interventions
Parent-Educator Action Response (PEAR), Daily Report Card
Behavioral
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Not listed
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 25, 2026, 7:56 AM EDT
Completed Not applicable Interventional

Pediatric Early Autism Recognition System: PEARS

NCT05153551
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Play-based assessment (RITA-T)
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Months and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Ann Arbor, Michigan • Brighton, Michigan • Northville, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 20, 2022 · Synced Oct 25, 2026, 7:56 AM EDT
Completed No phase listed Observational Results available

Antihypertensive Medication Exposure as Risk for Impaired Glucose Tolerance: A PEAR Sub-Study

NCT01099397
View directory record Official record
Conditions
Prediabetic State
Interventions
Oral glucose tolerance test
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 3, 2018 · Synced Oct 25, 2026, 7:56 AM EDT
Completed No phase listed Observational

Pharmacogenomic Evaluation of Antihypertensive Responses in Induced Pluripotent Stem (iPS) Cells Study

NCT01943383
View directory record Official record
Conditions
Hypertension
Interventions
iPSC
Genetic
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced Oct 25, 2026, 7:56 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Epigenetic Regulation of Human Adipose Tissue Distribution

NCT02728635
View directory record Official record
Conditions
Obesity
Interventions
Dual-energy X-ray absorptiometry (DEXA)/ Magnetic resonance imaging (MRI) and Magnetic resonance spectroscopy (MRS), Adipose tissue biopsies, FSIGTT/ RMR
Other · Procedure
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
18 Years to 45 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 25, 2026, 7:56 AM EDT
Completed Not applicable Interventional

Comprehensive CBT (Cognitive Behavioral Therapy) Via reSET App

NCT03826966
View directory record Official record
Conditions
Addiction, Opioid-use Disorder
Interventions
reSET
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Harrisburg, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 25, 2026, 7:56 AM EDT
Completed Phase 4 Interventional Results available

Long Term Antihypertensive Exposure and Adverse Metabolic Effects: PEAR Follow-Up Study

NCT01409434
View directory record Official record
Conditions
Drug Induced Hyperglycemia, Secondary Hyperlipidemia
Interventions
Oral Glucose Tolerance Test
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 16, 2014 · Synced Oct 25, 2026, 7:56 AM EDT