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ClinicalTrials.gov public records Last synced Sep 4, 2026, 11:36 PM EDT

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Showing 1–24 of 64 matching trials from the live ClinicalTrials.gov search.
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Conditions
Opioid Use Disorder
Interventions
PRC supported text + AI driven CSDH-enhanced text, AI driven CSDH-enhanced text only, Treatment as Usual (TAU)
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years to 99 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Mental Health, Substance Use Disorders, Co-occurring Mental and Substance Use Disorders
Interventions
Full MISSION-CJ, Peer Linkage Support
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Northampton, Massachusetts • West Boylston, Massachusetts
Conditions
Substance Use Disorder, Mental Health Disorder, Homelessness
Interventions
Employing Peer Outreach and Whole Health in Recovery (EMPOWER)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Palo Alto, California
Recruiting No phase listed Observational Accepts healthy volunteers

Emergency Medicine Peer Outreach Worker Engagement for Recovery

NCT06320015
Conditions
Substance Use Disorders, Overdose, Opioid Use Disorder, Alcohol Use Disorder
Interventions
Substance Misuse Assistance Response Team (SMART), Usual Care Group
Behavioral · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Not applicable Interventional Results available

The Health Access and Recovery Peer Program

NCT01725815
Conditions
Hypertension, Arthritis, Coronary Artery Disease, Hepatitis, Diabetes, Asthma, Hyperlipidemia, HIV
Interventions
HARP Intervention
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Psychotic Disorders, Substance Use
Interventions
Peer Approach to Substances in Early Psychosis Programs, Usual Care Peer Services
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
15 Years to 32 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
15
States / cities
Austin, Texas • Beaumont, Texas • Big Spring, Texas + 12 more
Not listed Not applicable Interventional Accepts healthy volunteers

Reducing Opioid Mortality in Illinois

NCT04925427
Conditions
Opioid Use, Opioid-use Disorder
Interventions
Case Management and Peer Recovery, Naloxone-Only
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
5
States / cities
Chicago, Illinois • Murphysboro, Illinois • Ottawa, Illinois + 2 more
Conditions
Mental Disorder
Interventions
Care Management
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Columbia, South Carolina
Conditions
Opiate Abuse, Opiate Overdose, Opioid-use Disorder
Interventions
Peer Addiction Counseling
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Greenville, South Carolina
Conditions
Suicidal Ideation, Suicide Attempt, Anxiety, Depression Disorders
Interventions
Peer Support Services Recovery
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 27 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Substance Use, Substance Abuse, Suicide, Adolescent
Interventions
WisePath for Teens, Peer Support Services (PSS), Control
Other · Behavioral · Device
Lead sponsor
Evidence-Based Practice Institute, Seattle, WA
Industry
Eligibility
13 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Baltimore, Maryland • Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers

Impact on Opioid Use of Bundling Medication-assisted Treatment With mHealth

NCT02712034
Conditions
Opioid Use Disorder
Interventions
MAT + A-CHESS, MAT
Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
417 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Polysubstance Addiction, Opioid Medication Assisted Treatment, Treatment Adherence, Retention in Care, Substance-Related Disorders
Interventions
Peer-Delivered Behavioral Activation ("Peer Activate")
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • College Park, Maryland + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

Supporting the Mental Health Workforce

NCT03709537
Conditions
Mental Health
Interventions
Mental Health Peer Workforce Support
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
366 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Culver City, California
Conditions
Substance Use Disorder, Mental Health Disorder, Homelessness
Interventions
Maintaining Maintaining Independence and Sobriety through Systems Integration Outreach and Networking- Criminal Justice, Maintaining Maintaining Independence and Sobriety through Systems Integration Outreach and Networking Peer Support
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Little Rock, Arkansas • Palo Alto, California • Bedford, Massachusetts
Conditions
Mental Health Disorders, Substance Use Disorders
Interventions
Full MISSION, Linkage Only Delivered by a Peer Specialist
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Worcester, Massachusetts
Conditions
Alcohol Use Disorder
Interventions
Peer recovery coaching (PRC), Brief Intervention (SBIRT)
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
18 Years to 75 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Greenville, South Carolina • Seneca, South Carolina
Conditions
Substance Use Disorders
Interventions
Contingency management, Usual Care
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Detroit, Michigan
Completed Not applicable Interventional Results available

Randomized Controlled Trial of Wellness Recovery Action Planning

NCT01024569
Conditions
Mental Disorders
Interventions
Wellness Recovery Action Planning (WRAP)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
555 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Peer Recovery Support for Opioid Use Disorder Treatment Retention

NCT07620171
Conditions
Opioid Use Disorder, Peer Recovery Supporters, Peer Recovery Coaching, Primary Care, Buprenorphine
Interventions
Peer Support
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Depression
Interventions
CBHH+AT, CBHH+SMT, CBHH
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Conditions
Opioid Use Disorder
Interventions
Certified Peer Support Specialist Intervention
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Greenville, South Carolina
Conditions
Clinical High Risk for Psychosis (CHR), Suicidal Ideation, Psychosis, Suicidal Behavior
Interventions
Suicide Prevention Intervention, Standard Care (in control arm)
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
12 Years to 30 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Los Angeles, California • San Diego, California
Conditions
Substance-Related Disorders
Interventions
SBIRT/eIntervention for those with moderate risk drug or alcohol use, SBIRT/eIntervention those assessed with high risk., SBIRT/TAU for those with moderate risk drug or alcohol use, SBIRT/TAU for those assessed with high risk.
Device · Other
Lead sponsor
Chess Mobile Health
Industry
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Kalamazoo, Michigan