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Conditions: Postpartum Pelvic Floor Function and Symptoms
Interventions: Digital therapeutic motion-based device; Device
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years and older · Female only
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Tampa, Florida • Columbus, Ohio

Conditions: Overactive Bladder, Urge Urinary Incontinence, Mixed Urinary Incontinence
Interventions: Leva device; Device
Lead sponsor: The Christ Hospital; Other
Eligibility: 18 Years to 85 Years · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Postpartum, Neuromuscular Adaptations, Abdominal Muscles, Pelvic Floor Dysfunctions, Physical Activity
Interventions: Progressive exercise, Active Straight Leg Raise Test, Active Straight Leg Raise Fatigue Task, Lower Extremity Strength Testing, Ultrasound imaging of abdominal wall, Pelvic Floor Muscle Strength Testing, Pelvic Floor Muscle Endurance Testing; Other · Diagnostic Test
Lead sponsor: Carroll University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Waukesha, Wisconsin

Conditions: Sexual Dysfunction, Pelvic Floor Disorders, Gynecologic Cancer
Interventions: Integrated Physical Therapy and Coping Skills Training; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Urinary Incontinence, Urge, Urinary Incontinence, Overactive Bladder, Incontinence, Urge, Incontinence, Urinary, Incontinence
Interventions: Tolterodine Tartrate ER, Mirabegron, Placebo; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 60 Years and older · Female only
Enrollment: 270 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 2
States / cities: Palo Alto, California • San Francisco, California

Conditions: Ventral Hernia, Ventral Incisional Hernia, Post Operative Pain
Interventions: PT Group, Usual Care; Other
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Pelvic Pain
Interventions: Yoga Therapy; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years and older · Female only
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Pelvic Floor Disfunction
Interventions: Osteopathic Manipulative Treatment (OMT); Procedure
Lead sponsor: Elizabeth Perrero; Other
Eligibility: 18 Years to 35 Years · Female only
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Cystitis, Interstitial
Interventions: ERICA; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older · Female only
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Myofacial Pain, Pelvic Pain, Myofascial Pelvic Pain, Chronic Pelvic Pain
Interventions: Near Infrared Imaging; Diagnostic Test
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Total Hip Arthroplasty, Osteoarthritis
Interventions: Functional Strength Integration (FSI), Control Group (CON); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years to 85 Years
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: No Disease or Condition is Being Directly Studied, The Focus of the Study in Healthy Volunteers
Interventions: Osteopathic manipulation, Sham; Other
Lead sponsor: Lake Erie College of Osteopathic Medicine; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Erie, Pennsylvania

Conditions: Multiple Sclerosis, Urinary Bladder, Overactive
Interventions: WeB, Standard pelvic floor physical therapy; Device · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Pelvic Pain
Interventions: Pelvic floor PT with biomarkers; Other
Lead sponsor: Kenneth Peters, MD; Other
Eligibility: 18 Years to 100 Years · Female only
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Dyspareunia
Interventions: Trigger Point Injections Triamcinolone Acetonide, Bupivacaine Hydrochloride, Pelvic Rehabilitation; Drug · Procedure
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older · Female only
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Low Anterior Resection Syndrome, Rectal Carcinoma
Interventions: Dietary Fiber, Enema Administration, Loperamide Hydrochloride, Physical Therapy, Questionnaire Administration, X-Ray Imaging; Dietary Supplement · Procedure · Drug + 1 more
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Localized Prostate Carcinoma, Locally Advanced Prostate Carcinoma, Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8, Stage II Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8
Interventions: Biospecimen Collection, Discussion, Exercise Intervention, Interview, Medical Device Usage and Evaluation, Physical Examination, Physical Performance Testing, Questionnaire Administration, Recreational Therapy; Procedure · Other
Lead sponsor: University of Southern California; Other
Eligibility: 55 Years to 85 Years · Male only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 2
States / cities: Los Angeles, California

Conditions: Levator Ani Syndrome
Interventions: Nifedipine, Placebo Ointment Base; Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Chronic Pelvic Pain
Interventions: Empowered Relief (ER) Therapy; Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Urinary Incontinence
Interventions: Multi-modal rehabilitation program, Pelvic Floor Physical therapy; Other
Lead sponsor: Howard University; Other
Eligibility: 65 Years and older · Female only
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Prostate Cancer, Urinary Incontinence, Erectile Dysfunction
Interventions: Sex Therapy, Pelvic Floor Physical Therapy, Vacuum Erection Device (VED); Behavioral · Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Prostate Cancer
Interventions: Radiation, Radical Prostatectomy; Radiation · Procedure
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 70 Years · Male only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2013
U.S. locations: 2
States / cities: Durham, North Carolina • Richmond, Virginia

Conditions: Low Back Pain
Interventions: Spinal Manipulation, Spinal Mobilization, Static Touch; Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 40 Years
Enrollment: 159 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Prostate Cancer
Interventions: Kegel exercises, Pelvic Floor Muscle Exercise Program with biofeedback, Questionnaires, Interviews; Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older · Male only
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 7
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

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Postpartum pElvic Assisted Recovery With Leva

Pelvic Floor Muscle Training With Leva System for Urge Incontinence

Postpartum Exercise Intervention

Improving Women's Function After Pelvic Radiation

TReating Incontinence for Underlying Mental and Physical Health

The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery

Program to Overcome Pelvic Pain With Yoga

The Impact of Osteopathic Manipulative Treatment on Pelvic Floor Dysfunction, Activity, and Gait in Female Runners

Smartphone-based Self-care Education Program for Women With Interstitial Cystitis: Educational Remote IC Aide

Measuring Pelvic Floor Muscle Fitness Before and After Treatment

Improving Rehabilitation Outcomes After Total Hip Arthroplasty

Optimizing Lymphatic Pumping for Influenza Vaccine Responses in Vulnerable Populations

Wearables for the Bladder: an In-home Treatment Feasibility Pilot Study

Pelvic Floor Physical Therapy-Biomarkers Project

Trigger Point Injections and Pelvic Rehabilitation for the Treatment of Pelvic Floor Myalgia and Sexual Pain

A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients

Golf Recreational Exercise for Enhanced Survivorship in Prostate Cancer Survivors

A Study Examining the Use of Vaginal Nifedipine With Pelvic Floor Physical Therapy for Levator Myalgia and Pelvic Pain

Empowered Relief for Chronic Pelvic Pain

Functional Assessment and Muscle Evaluation Through Exercise Trial

Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment

Preoperative Radiation Therapy for High Risk Prostate Cancer

Central Mechanisms of Intervention for Low Back Pain

A Study of a Pelvic Floor Muscle Exercise Program Before and After Radical Prostatectomy