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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:49 AM EDT

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Showing 121–144 of 183 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Percocet Clear all
Terminated Phase 4 Interventional Results available

Opioid Free vs. Standard Perioperative Pain Regimen for Anterior Cervical Discectomy and Fusion (ACDF) Surgery

NCT04990804
View directory record Official record
Conditions
Opioid Use, Spinal Diseases, Surgery--Complications, Surgery, Postoperative Pain
Interventions
Opioid Analgesic, Opioid-Free Postoperative Pain Regimen
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Oct 21, 2026, 4:49 AM EDT
Withdrawn Phase 4 Interventional

Pilot Study: Effect of Dexamethasone vs Vicodin in Reducing Post-operative Pain

NCT04008043
View directory record Official record
Conditions
Oral Surgery
Interventions
Vicodin, Dexamethasone
Drug
Lead sponsor
Boston University
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Phase 4 Interventional

Open-Label Study of Oxycodone/APAP to Treat Post-Operative Pain Following Arthroscopic Knee Surgery

NCT02391844
View directory record Official record
Conditions
Disorder of Knee
Interventions
Oxycodone
Drug
Lead sponsor
International Clinical Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2016 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Phase 2 Interventional Results available

Analgesic Efficacy of (MSIR)/Acetaminophen vs. Oxycodone/Acetaminophen (Percocet)

NCT03088826
View directory record Official record
Conditions
Pain Management
Interventions
Morphine Sulfate, Oxycodone, Acetaminophen
Drug
Lead sponsor
Antonios Likourezos
Other
Eligibility
18 Years to 64 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy of COV795 in Moderate to Severe Post-Operative Bunionectomy Pain With an Open-label Extension

NCT01484652
View directory record Official record
Conditions
Pain, Postoperative, Bunion
Interventions
COV795, Placebo
Drug
Lead sponsor
Mallinckrodt
Industry
Eligibility
18 Years to 75 Years
Enrollment
329 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
5
States / cities
Bakersfield, California • Pasadena, California • Pasadena, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2016 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Phase 2 Interventional Results available

Celecoxib After Tonsillectomy

NCT02934191
View directory record Official record
Conditions
Tonsillectomy
Interventions
Celecoxib, Placebo, Acetaminophen, Oxycodone
Drug · Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
3 Years to 11 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Phase 3 Interventional Results available

Study of COV795 in Subjects With Osteoarthritis or Chronic Low Back Pain

NCT01451385
View directory record Official record
Conditions
Osteoarthritis, Low Back Pain
Interventions
COV795
Drug
Lead sponsor
Mallinckrodt
Industry
Eligibility
18 Years and older
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
42
States / cities
Tucson, Arizona • Anaheim, California • Buena Park, California + 33 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2020 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Not applicable Interventional

Acupuncture for Vasectomy Pre-procedural Anxiety and Pain Control in the Primary Care Setting

NCT03938415
View directory record Official record
Conditions
Acupuncture, Pain, Postoperative, Vasectomy
Interventions
Acupuncture, Standardized pre-procedure medications
Procedure · Other
Lead sponsor
Matthew Snyder
Federal
Eligibility
25 Years and older · Male only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Early Phase 1 Interventional

NSAIDS Versus Opioids in Acute SER II Ankle Fractures

NCT02373254
View directory record Official record
Conditions
Ankle Fracture
Interventions
Ibuprofen, Acetaminophen/hydrocodone
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 60 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2017 · Synced Oct 21, 2026, 4:49 AM EDT
Recruiting No phase listed Observational

Continuous Observational Monitoring Program for Allay™ Hydrogel Cap Safety and Success Study

NCT07246980
View directory record Official record
Conditions
Peripheral Nerve Injuries
Interventions
Nerve Cap
Device
Lead sponsor
Tulavi Therapeutics,Inc.
Industry
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
5
States / cities
Redwood City, California • Englewood, Colorado • Orlando, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 21, 2026, 4:49 AM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Effect of Postoperative Ketorolac on Bone Healing After Joint Fusion

NCT04872283
View directory record Official record
Conditions
Ketorolac, Joint Fusion
Interventions
great toe (1st metatarsophalangeal joint) fusion, IV Ketorolac, Ketorolac Pill, 5/325mg Oxycodone-Acetaminophen, Aspirin 81Mg Ec Tab
Procedure · Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2021 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Not applicable Interventional

Non-opioid Based Pain Control After Thyroidectomy

NCT03988075
View directory record Official record
Conditions
Pain, Thyroidectomy
Interventions
Acetaminophen and hydrocodone based pain control, Acetaminophen and ibuprofen based pain control
Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Oct 21, 2026, 4:49 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Green Light Effect on Sleep

NCT04828473
View directory record Official record
Conditions
Sleep
Interventions
Allay Lamp
Device
Lead sponsor
The Green Light Study Center
Other
Eligibility
40 Years to 95 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Mar 15, 2022 · Synced Oct 21, 2026, 4:49 AM EDT
Terminated Phase 4 Interventional Results available

NSAIDs vs Opioids for Post-op Pain in Supracondylar Humerus Fractures

NCT04905563
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Acetaminophen-Hydrocodone, Acetaminophen and Ibuprofen
Drug
Lead sponsor
Le Bonheur Children's Hospital
Other
Eligibility
4 Years to 13 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 8, 2024 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Phase 4 Interventional Results available

Postoperative Pain Control in Septum and Sinus Surgery

NCT04149964
View directory record Official record
Conditions
Post-operative Pain, Sinus Surgery
Interventions
Acetaminophen 325 mg Oral Tablet, Acetaminophen 650 mg Oral Tablet, OxyCODONE 5 mg Oral Tablet, Acetaminophen/Hydrocodone 325 mg/7.5 mg oral tablet
Drug
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Farmington Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Oct 21, 2026, 4:49 AM EDT
Not listed Not applicable Interventional

Green Light Effects on Anxiety

NCT04871087
View directory record Official record
Conditions
Anxiety
Interventions
Green Light
Device
Lead sponsor
The Green Light Study Center
Other
Eligibility
18 Years to 95 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Delray Beach, Florida
Source: ClinicalTrials.gov public record
Updated Mar 15, 2022 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Phase 4 Interventional Results available

Supracondylar Humerus Fracture (SCHF) Post-Op Study Between Opioid and Non-Opioid Pain Management

NCT06187584
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Hydrocodone/acetaminophen, Acetaminophen, Ibuprofen
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
5 Years to 9 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Phase 3 Interventional Results available

Comparing the Efficacy of Oral Opioids for Outpatient Acute Pain Management After ED Discharge Discharge

NCT01402375
View directory record Official record
Conditions
Analgesia After ED Discharge for Extremity Injuries
Interventions
Hydrocodone (first trial), Codeine (first trial), Oxycodone (for second trial), Codeine (for second trial), Oxycodone (third trial), Hydrocodone (third trial)
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
21 Years to 64 Years
Enrollment
720 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Phase 4 Interventional Results available

Pharmacokinetic Study of Hydrocodone/APAP in Chronic Pain Patients

NCT01517295
View directory record Official record
Conditions
Chronic Pain
Interventions
Hydrocodone
Drug
Lead sponsor
NEMA Research, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
2
States / cities
Naples, Florida • Leawood, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2016 · Synced Oct 21, 2026, 4:49 AM EDT
Withdrawn Phase 2Phase 3 Interventional

Opioid-Free Pain Control Regiment Following Robotic Radical Prostatectomy

NCT04939987
View directory record Official record
Conditions
Radical Prostatectomies
Interventions
Tramadol, Gabapentin, Hydrocodone-Acetaminophen, Oxycodone-Acetaminophen, Ketorolac, Acetaminophen, Ketorolac tromethamine, Ketamine
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years to 75 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 6, 2022 · Synced Oct 21, 2026, 4:49 AM EDT
Recruiting Not applicable Interventional

Alleviant ALLAY-HF Study

NCT05685303
View directory record Official record
Conditions
Heart Failure
Interventions
Alleviant ALV1 System, Sham-Control
Device · Other
Lead sponsor
Alleviant Medical, Inc.
Industry
Eligibility
40 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
56
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 50 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 21, 2026, 4:49 AM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Effect of Ropivacaine During Popliteal Nerve Block in Foot and Ankle Surgery

NCT04872322
View directory record Official record
Conditions
Popliteal Nerve Block, Foot Surgery, Ankle Surgery
Interventions
Ropivacaine 0.5% Injectable Solution, Ropivacaine 0.25% Injectable Solution, Percocet Pill, Norco Pill, Foot/Ankle Surgery
Drug · Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2021 · Synced Oct 21, 2026, 4:49 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic Meniscus Surgery

NCT04246541
View directory record Official record
Conditions
Meniscus Tear, Tibial, Pain, Postoperative, Postoperative Complications, Ketorolac Adverse Reaction, Opioid Use
Interventions
Ketorolac, Oxycodone-Acetaminophen
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Oct 21, 2026, 4:49 AM EDT
Terminated Phase 4 Interventional Results available

Post-operative Pain Management in Children With Supracondylar Humerus Fractures

NCT05640674
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Ibuprofen, Hydrocodone/acetaminophen, Acetaminophen
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
3 Years to 12 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 21, 2026, 4:49 AM EDT