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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Percutaneous Nephrolithotomy Clear all
Terminated Phase 4 Interventional

Regional Erector Spinae Analgesic Block vs Standard of Care Undergoing Percutaneous Nephrolithotomy

NCT04663269
View directory record Official record
Conditions
Kidney Stone, Surgery
Interventions
4mg PF Dexamethasone, Control Test
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Sep 2, 2026, 5:35 PM EDT
Completed No phase listed Observational

Asymptomatic Renal Calculi in Recurrent Urinary Tract Infections

NCT04495699
View directory record Official record
Conditions
Urinary Tract Infections, Kidney Stone
Interventions
None - observational
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
5
States / cities
Phoenix, Arizona • San Diego, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Sep 2, 2026, 5:35 PM EDT
Completed Phase 4 Interventional Results available

Intravenous Ketorolac for Postoperative Pain in Percutaneous Nephrolithotomy

NCT00765128
View directory record Official record
Conditions
Renal Calculus, Kidney Stones
Interventions
Ketorolac, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 26, 2012 · Synced Sep 2, 2026, 5:35 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy

NCT02579161
View directory record Official record
Conditions
Kidney Stones
Interventions
cephalosporins, Fluoroquinolones, Clindamycin, Ampicillin/Gentamicin
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
2
States / cities
Manhasset, New York • New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Sep 2, 2026, 5:35 PM EDT
Not listed Phase 4 Interventional

Struvite Stones Antibiotic Study

NCT02375295
View directory record Official record
Conditions
Kidney Stones
Interventions
ciprofloxacin, cotrimoxazole-trimethoprim, macrodantin
Drug
Lead sponsor
University of British Columbia
Other
Eligibility
19 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
11
States / cities
Scottsdale, Arizona • San Diego, California • Baltimore, Maryland + 8 more
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Sep 2, 2026, 5:35 PM EDT
Completed Not applicable Interventional Results available

Intraoperative Cone-beam CT for Percutaneous Nephrolithotomy

NCT04556396
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Cone beam CT
Diagnostic Test
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Sep 2, 2026, 5:35 PM EDT
Active, not recruiting No phase listed Observational

Feasibility of Radiation-Free Percutaneus Nephrolithotomy for Kidney Stones

NCT06922006
View directory record Official record
Conditions
Kidney Stones
Interventions
Percutaneus nephrolithotomy (PCNL)
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
Not listed
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Sep 2, 2026, 5:35 PM EDT
Completed Phase 3 Interventional Results available

Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery.

NCT03584373
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Ketorolac Oral Tablet [Toradol], Acetaminophen, Oxycodone Acetaminophen
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 17, 2023 · Synced Sep 2, 2026, 5:35 PM EDT
Completed No phase listed Observational

Percutaneous Nephrolithotomy: A Registry and Database

NCT00159393
View directory record Official record
Conditions
Nephrolithiasis
Interventions
registry and database
Other
Lead sponsor
Indiana Kidney Stone Institute
Other
Eligibility
18 Years and older
Enrollment
1,697 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2018
U.S. locations
2
States / cities
Carmel, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Sep 2, 2026, 5:35 PM EDT
Completed Not applicable Interventional

Renogram Study With Percutaneous Nephrolithotomy (PERC): Alterations in Renal Blood Flow as a Consequence of PERC

NCT00169741
View directory record Official record
Conditions
Renal Calculi
Interventions
Renogram
Other
Lead sponsor
Indiana Kidney Stone Institute
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 22, 2016 · Synced Sep 2, 2026, 5:35 PM EDT
Not yet recruiting Not applicable Interventional

The LARC Robot Simplifies Renal Access In Percutaneous Nephrolithotomy

NCT07211555
View directory record Official record
Conditions
Renal Stone Disease, Kidney Calculi, Refractory Kidney Stones, Kidney Stones
Interventions
LARC Robotic System (Micromate™ Version 3.0)
Device
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Celebration, Florida
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Sep 2, 2026, 5:35 PM EDT
Recruiting Not applicable Interventional

HoYAG vs TFL in miniPCNL With ClearPetra

NCT07087977
View directory record Official record
Conditions
Nephrolithiasis, Kidney Stone
Interventions
HoYAG laser, TFL laser platform
Device
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 2, 2026, 5:35 PM EDT
Recruiting No phase listed Observational

Serum Endotoxin Assay to Predict the Development of Postoperative Infectious Complications and Systemic Inflammatory Response Following Percutaneous Nephrolithotomy.

NCT04669886
View directory record Official record
Conditions
Nephrolithiasis, Urosepsis
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 2, 2026, 5:35 PM EDT
Completed Not applicable Interventional

Trial Comparing Relapse Rates Between Standard Ureteroscopic Removal Of Ureteral Stone And Standard Removal With Additional Ureterorenic Clearing Of Non-Symptomatic Stones In The Kidney

NCT02210650
View directory record Official record
Conditions
Ureteral Stones, Kidney Stones
Interventions
Symptomatic stone removal, Asymptomatic kidney stones and ureteral stone removed
Procedure
Lead sponsor
Indiana Kidney Stone Institute
Other
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
4
States / cities
Indianapolis, Indiana • Minneapolis, Minnesota • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Sep 2, 2026, 5:35 PM EDT
Completed Not applicable Interventional

Quality of Life in Kidney Stone Patients Undergoing Surgery

NCT02625051
View directory record Official record
Conditions
Kidney Calculi, Quality of Life
Interventions
Ureteroscopy, Percutaneous nephrolithotomy
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Sep 2, 2026, 5:35 PM EDT
Not listed Not applicable Interventional

Paravertebral Block for Percutaneous Nephrolithotomy

NCT01480102
View directory record Official record
Conditions
Post Operative Pain
Interventions
Group A-Paravertebral block, Group B- No block
Drug · Other
Lead sponsor
Loyola University
Other
Eligibility
18 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Sep 2, 2026, 5:35 PM EDT
Completed No phase listed Observational

Simulated Rehearsal for Percutaneous Nephrolithotomy

NCT03272529
View directory record Official record
Conditions
Nephrolithotomy
Interventions
Patient-specific simulated rehearsals, Idealized simulated rehearsals, Standard simulation
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Sep 2, 2026, 5:35 PM EDT
Enrolling by invitation Not applicable Interventional

Comparison of Holmium Laser and Thulium Laser for Mini PCNL

NCT06266793
View directory record Official record
Conditions
Nephrolithiasis, Percutaneous Nephrolithotomy
Interventions
Holmium Laser, Thulium Laser
Device
Lead sponsor
MaineHealth
Other
Eligibility
21 Years to 90 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Sep 2, 2026, 5:35 PM EDT
Recruiting Not applicable Interventional

ESP Block vs Control for Pain Control Following Percutaneous Nephrolithotomy

NCT05024344
View directory record Official record
Conditions
Nephrolithotomy, Percutaneous
Interventions
Erector Spinae Plane Block, Ropivacaine 0.5% Injectable Solution, Dexamethasone
Procedure · Drug
Lead sponsor
University of Tennessee Medical Center
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 2, 2026, 5:35 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])

NCT02384200
View directory record Official record
Conditions
Nephrolithiasis, Urinary Tract Infections
Interventions
nitrofurantoin monohydrate/macrocrystalline capsules, ampicillin, gentamicin, vancomycin, ceftriaxone
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
7
States / cities
Phoenix, Arizona • San Diego, California • San Francisco, California + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Sep 2, 2026, 5:35 PM EDT
Recruiting Not applicable Interventional

Tract Closure in PCNL

NCT07668817
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Floseal, Surgicel, Surgiflo, Balloon Tamponade
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 2, 2026, 5:35 PM EDT
Not listed Not applicable Interventional

Ambulatory Versus Inpatient Percutaneous Nephrolithotomy

NCT04690010
View directory record Official record
Conditions
Kidney Calculi
Interventions
Ambulatory tubeless PCNL, Inpatient PCNL with nephrostomy tube
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Sep 2, 2026, 5:35 PM EDT
Completed Phase 3 Interventional

Standard Percutaneous Nephrolithotomy Percutaneous Nephrolithotomy (PNL) Versus Tubeless PNL Versus Tubeless Stentless PNL

NCT01548196
View directory record Official record
Conditions
Nephrolithotomy
Interventions
Standard Percutaneous nephrolithotomy
Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 16, 2015 · Synced Sep 2, 2026, 5:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy

NCT00873054
View directory record Official record
Conditions
Kidney Stones
Interventions
Not listed
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years to 90 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Feb 2, 2014 · Synced Sep 2, 2026, 5:35 PM EDT