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ClinicalTrials.gov public records Last synced Sep 11, 2026, 1:31 PM EDT

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Showing 1–24 of 85 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Percutaneous ablation Clear all
Completed Not applicable Interventional

Percutaneous Cryoablation in Treating Patients With Painful Bone Metastases

NCT00608855
View directory record Official record
Conditions
Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
questionnaire administration, cryosurgery, pain therapy, quality-of-life assessment
Other · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 120 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2013
U.S. locations
10
States / cities
Jacksonville, Florida • Ann Arbor, Michigan • Detroit, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Sep 11, 2026, 1:31 PM EDT
Completed Not applicable Interventional Results available

The EMPrint™ Ablate and RESect Study in Patients With Metastatic Lung Tumors (EMPRESS)

NCT02323854
View directory record Official record
Conditions
Lung Cancer
Interventions
Ablation, Surgical Resection
Device · Procedure
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
3
States / cities
Rochester, Minnesota • New York, New York • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 6, 2018 · Synced Sep 11, 2026, 1:31 PM EDT
Recruiting Not applicable Interventional

Computer Guided Microwave Liver Ablation

NCT07226869
View directory record Official record
Conditions
Hepatocellular Carcinoma (HCC)
Interventions
Computer-Assisted Microwave Liver Ablation
Device
Lead sponsor
NE Scientific INC
Industry
Eligibility
18 Years to 90 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Boston, Massachusetts • Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 11, 2026, 1:31 PM EDT
Terminated Not applicable Interventional

A Randomized Controlled Trial of Leg Length Discrepancy Techniques

NCT02260856
View directory record Official record
Conditions
Leg Length Discrepancy
Interventions
Tantalum Beads & Injector, Percutaneous Drill Epiphysiodesis, Percutaneous Screw Epiphysiodesis
Device · Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
7 Years to 18 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Sep 11, 2026, 1:31 PM EDT
Completed Not applicable Interventional Results available

Comparison of Percutaneous Closure to Manual Compression for Hemostasis

NCT04180540
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Percutaneous Closure, Manual Compression
Device · Other
Lead sponsor
Michael S. Lloyd
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 6, 2022 · Synced Sep 11, 2026, 1:31 PM EDT
Withdrawn Phase 1 Interventional

Phase-I Trial of Pembrolizumab and Percutaneous Cryoablation Combination Followed by Nephron-Sparing Surgery or Cytoreductive Nephrectomy in Locally Advanced and Metastatic Renal Cell Carcinomas

NCT03189186
View directory record Official record
Conditions
Renal Cell Carcinoma, Metastatic Kidney Cancer
Interventions
Pembrolizumab Injection [Keytruda], Cryoablation, Nephrectomy
Drug · Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Sep 11, 2026, 1:31 PM EDT
Enrolling by invitation No phase listed Observational

Measuring Symptom Relief After Radiofrequency Ablation of the Thyroid

NCT05501041
View directory record Official record
Conditions
Thyroid
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Sep 11, 2026, 1:31 PM EDT
Recruiting No phase listed Observational

A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy

NCT06859801
View directory record Official record
Conditions
Bone Cancer Metastatic
Interventions
Percutaneous Ablation, Radiation Therapy
Device · Radiation
Lead sponsor
Society of Interventional Oncology
Other
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
8
States / cities
San Diego, California • Miami, Florida • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 11, 2026, 1:31 PM EDT
Recruiting Phase 1Phase 2 Interventional

Prospective IR-led Sedation Feasibility

NCT07443254
View directory record Official record
Conditions
Anesthesia, Sedation and Analgesia, Interventional Radiology
Interventions
ketamine, Fentanyl (IV), Midazolam
Drug
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 11, 2026, 1:31 PM EDT
Enrolling by invitation Not applicable Interventional

Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Postoperative Pain After Mastectomy

NCT05444361
View directory record Official record
Conditions
Mastectomy; Lymphedema
Interventions
Cryoneurolysis, Sham Comparator
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
5
States / cities
Los Angeles, California • San Diego, California • Gainesville, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 11, 2026, 1:31 PM EDT
Terminated Not applicable Interventional Results available

Trial Comparing PLA to HIGRT (PROVE-HCC)

NCT03402607
View directory record Official record
Conditions
Hepatocellular Carcinoma
Interventions
Percutaneous Local Ablation, Hypofractionated Image Guided Radiation Therapy
Procedure · Radiation
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Sep 11, 2026, 1:31 PM EDT
Terminated Phase 1 Interventional

Local Ablative Strategies After Endovascular Radioembolization

NCT02611661
View directory record Official record
Conditions
Metastatic Colorectal Cancer
Interventions
PET/MRI, Percutaneous ablation, Stereotactic body radiotherapy
Device · Radiation
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Sep 11, 2026, 1:31 PM EDT
Terminated Phase 1 Interventional

Safety and Efficacy of Cryoablation for Abdominal Pain Associated With Pancreatic Cancer

NCT01335945
View directory record Official record
Conditions
Pain, Pancreatic Cancer
Interventions
Cryoablation
Procedure
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
3
States / cities
Detroit, Michigan • Stony Brook, New York • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 15, 2021 · Synced Sep 11, 2026, 1:31 PM EDT
Terminated Phase 4 Interventional Results available

Percutaneous HydroDiscectomy Compared to TESI for Radiculopathy

NCT02414698
View directory record Official record
Conditions
Lumbar Herniated Disc
Interventions
Percutaneous Hydrodiscectomy, TESI
Procedure · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2020 · Synced Sep 11, 2026, 1:31 PM EDT
Withdrawn Not applicable Interventional

Evaluation of the XACT Robotic System for Image-guided Percutaneous Lung Procedures

NCT04612985
View directory record Official record
Conditions
CT-guided Minimally Invasive Procedures e.g. Biopsies
Interventions
XACT Robotic System
Device
Lead sponsor
Xact Robotics Ltd.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Sep 11, 2026, 1:31 PM EDT
Withdrawn Phase 1 Interventional

Radiofrequency Ablation for Liver Abscesses From Chronic Granulomatous Disease

NCT01851460
View directory record Official record
Conditions
Chronic Granulomatous Diseases (CGD) and Liver Lesions
Interventions
Cool-tip RF Ablation System
Device
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Sep 11, 2026, 1:31 PM EDT
Recruiting Not applicable Interventional

Prospective Evaluation of the Pulse Biosciences nPulse™ Vybrance™ Percutaneous Electrode System

NCT07287176
View directory record Official record
Conditions
Thyroid Nodule, Thyroid Goiter, Ablation
Interventions
nPulse Vybrance Percutaneous Electrode System
Device
Lead sponsor
Pulse Biosciences, Inc.
Industry
Eligibility
22 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Sarasota, Florida • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 11, 2026, 1:31 PM EDT
Terminated Not applicable Interventional Results available

TAE and MWA Combination Therapy in Early-stage Hepatocellular Carcinoma

NCT02704130
View directory record Official record
Conditions
Hepatocellular Carcinoma, Hepatoma, Liver Cancer, Adult, Liver Cell Carcinoma, Liver Cell Carcinoma, Adult
Interventions
Transarterial embolization, Microwave Ablation
Device · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Sep 11, 2026, 1:31 PM EDT
Completed Not applicable Interventional

Evaluation of the Safety, Effectiveness & Usability of the XACT Robotic System for Image Guided Percutaneous Procedures

NCT03008603
View directory record Official record
Conditions
CT-guided Minimally Invasive Procedures e.g., Biopsies
Interventions
XACT Robotic System
Device
Lead sponsor
Xact Robotics Ltd.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Sep 11, 2026, 1:31 PM EDT
Completed No phase listed Observational

Radiofrequency Ablation of Painful Soft Tissue Neoplasms

NCT00041886
View directory record Official record
Conditions
Soft Tissue Neoplasms
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 11, 2026, 1:31 PM EDT
Recruiting Not applicable Interventional

Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients

NCT04933435
View directory record Official record
Conditions
Liver Cancer
Interventions
Quality of life questionnaires
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Sep 11, 2026, 1:31 PM EDT
Completed No phase listed Observational

Radiofrequency Nerve Ablation Versus Sham to Treat Chronic Low Back Pain Caused by Sacroiliac Joint Dysfunction

NCT01104051
View directory record Official record
Conditions
Sacroiliac Joint Dysfunction
Interventions
Not listed
Lead sponsor
Coastal Orthopedics & Sports Medicine
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Jul 28, 2015 · Synced Sep 11, 2026, 1:31 PM EDT
Recruiting Not applicable Interventional

Nanosecond Pulsed Field Ablation in the Management of T1N0M0 Papillary Thyroid Carcinoma

NCT07218315
View directory record Official record
Conditions
Thyroid Carcinoma
Interventions
CellFX nsPFA Percutaneous Electrode System
Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
2
States / cities
Sarasota, Florida • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 11, 2026, 1:31 PM EDT
Enrolling by invitation No phase listed Observational

Patient-reported Outcomes Following Percutaneous Ablation of Desmoid Tumors

NCT07755176
View directory record Official record
Conditions
Desmoid Tumor, Aggressive Fibromatoses
Interventions
Desmoid tumor ablation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 11, 2026, 1:31 PM EDT