Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 6, 2026, 1:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–37 of 37 matching trials from the live ClinicalTrials.gov search.
Conditions
Periodontitis, Diabetes Mellitus Type 2
Interventions
local antibiotic application of topical minocycline, Scaling and Root Planing
Drug · Procedure
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Role of Infected Blood Dendritic Cells in Heart Disease Risk

NCT01568944
Conditions
Chronic Periodontitis
Interventions
Oral Antibiotic and Oral Rinse, Standard Treatment
Drug · Procedure
Lead sponsor
Augusta University
Other
Eligibility
40 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Periodontitis
Interventions
SRP + MM, Scaling and Root Planing (SRP)
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Morgantown, West Virginia
Conditions
Moderate to Advanced Chronic Periodontitis
Interventions
locally-applied minocycline HCl (1 mg), scaling and root planing (Sc/RP)
Drug · Procedure
Lead sponsor
University of Nebraska
Other
Eligibility
40 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Lincoln, Nebraska • Omaha, Nebraska
Conditions
Periodontitis (Stage 3)
Interventions
Emanate Perio PODS
Device
Lead sponsor
McGuire Institute
Industry
Eligibility
30 Years to 75 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
8
States / cities
Fullerton, California • New London, Connecticut • Boston, Massachusetts + 5 more
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Scaling and Root Planing (SRP) With and Without Minocycline HCl Microspheres, 1 mg

NCT03762915
Conditions
SRP, Minocycline HCl Microspheres, Biomarkers
Interventions
minocycline HCl microspheres
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Cardiovascular Diseases, Diabetes Type 2
Interventions
Subgingival chlorhexidine irrigation, Dental Supplies, Periodonal Treatment
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
786 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Kannapolis, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Utilization of a Periodontal Endoscope in Nonsurgical Periodontal Therapy

NCT05293301
Conditions
Periodontitis, Adult
Interventions
Use of Periodontal Endoscope (Perioscopy®) to enhance visualization while performing teeth deep cleaning, Use of traditional loupes to enhance magnification to enhance visualization while performing teeth deep cleaning
Device
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
Periodontitis, Periodontal Diseases
Interventions
metronidazole
Drug
Lead sponsor
The Forsyth Institute
Other
Eligibility
35 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Periodontitis, Chronic Kidney Disease
Interventions
Scaling root planing, Supragingival Prophylaxis
Procedure
Lead sponsor
UConn Health
Other
Eligibility
21 Years to 85 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Chronic Periodontitis
Interventions
PeriZone PerioPatch, Scaling and root planing alone
Device · Procedure
Lead sponsor
MIS Implant Technologies, Ltd
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Norfolk, Virginia
Conditions
Periodontal Bone Loss
Interventions
Enamel Matrix Proteins Derivative, Saline
Drug · Other
Lead sponsor
University of Nebraska
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lincoln, Nebraska
Conditions
Periodontal Diseases, Periodontitis, Apical, Chronic Nonsuppurative, Suppuration of Gingival Crevice
Interventions
Scaling and Root Planing, Diode Laser + Scaling and Root Planing
Procedure
Lead sponsor
University of Nebraska
Other
Eligibility
30 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Lincoln, Nebraska