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ClinicalTrials.gov public records Last synced Oct 10, 2026, 9:12 AM EDT

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Showing 97–120 of 236 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Perioperative surgical care Clear all
Completed Not applicable Interventional Results available

Decision Support for Intraoperative Low Blood Pressure

NCT02726620
View directory record Official record
Conditions
Hypotension
Interventions
Attending real-time decision support, In-room real-time decision support, Attending feedback emails, In-room provider feedback emails, Anesthesia Information Management System (AIMS), Perioperative Data Warehouse (PDW), General anesthesia, Pager system, Central neuraxial anesthesia, Non-cardiac surgery, Propofol, Sevoflurane, Desflurane, Isoflurane, Ephedrine, Phenylephrine, Norepinephrine, Epinephrine, Dobutamine, Dopamine, Isoproterenol, Milrinone, Atropine, Glycopyrrolate, Vasopressin, Terlipressin, Sodium Chloride 0.9%, Ringer's lactate, Hydroxyethyl starch solutions, Fresh Frozen Plasma, Packed Red Blood Cells, Albumin solutions, Plasma-Lyte, Lidocaine, Bupivacaine, Levobupivacaine, Ropivacaine, Mepivacaine, Tetracaine, Prilocaine, Procaine, Chloroprocaine, Benzocaine, Articaine
Procedure · Device · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years to 100 Years
Enrollment
22,435 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 16, 2019 · Synced Oct 10, 2026, 9:12 AM EDT
Completed No phase listed Observational

Preoperative Prehabilitation Program For Geriatric Patients in a Rural Healthcare Setting

NCT06518369
View directory record Official record
Conditions
Surgery
Interventions
Prehabilitation
Other
Lead sponsor
The Guthrie Clinic
Other
Eligibility
60 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Sayre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2025 · Synced Oct 10, 2026, 9:12 AM EDT
Recruiting Not applicable Interventional

INCLUDE Program: A Perioperative Wellness Program Tailored for Black Surgical Patients

NCT07283783
View directory record Official record
Conditions
Surgery
Interventions
Wellness Program
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 10, 2026, 9:12 AM EDT
Completed Not applicable Interventional

The Effects of Perioperative Music Therapy on Women Undergoing Breast Biopsy Surgery

NCT01669733
View directory record Official record
Conditions
Abnormal Breast Tissue
Interventions
Music, Standard of Care
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
19 Years and older · Female only
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 24, 2015 · Synced Oct 10, 2026, 9:12 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Impact of the Enhanced Recovery After Surgery System for Colorectal Surgery

NCT02997293
View directory record Official record
Conditions
ColoRectal Cancer and Inflammatory Bowel Disease
Interventions
Enhanced Recovery protocol
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2028
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 10, 2026, 9:12 AM EDT
Completed Not applicable Interventional Results available

Perioperative Palliative Care Surrounding Cancer Surgery for Patients & Their Family Members

NCT03611309
View directory record Official record
Conditions
Gastrointestinal Cancer
Interventions
Surgeon-palliative care team co management, Surgeon team alone management
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
379 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
5
States / cities
Stanford, California • Baltimore, Maryland • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 10, 2026, 9:12 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Risk Factors for Post-Operative Respiratory Complications in Patients at Risk for OSA

NCT02729077
View directory record Official record
Conditions
Respiratory Complications
Interventions
Pulse Oximetry
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 75 Years
Enrollment
324 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2021 · Synced Oct 10, 2026, 9:12 AM EDT
Completed Not applicable Interventional Results available

A Pilot Study Investigating the nCAP Signal Relief Patch in Subjects Undergoing Primary Hip or Knee Replacement Surgery

NCT05252858
View directory record Official record
Conditions
Opioid Use, Pain, Post Operative
Interventions
nCAP Signal Relief Patch, Standard of Care
Device · Other
Lead sponsor
Jacques E. Chelly
Other
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 10, 2026, 9:12 AM EDT
Recruiting Phase 2 Interventional

Telehealth Intervention for Ostomy Self-Management

NCT06528990
View directory record Official record
Conditions
Colorectal Cancer, Bladder Cancer
Interventions
Telehealth Intervention, Standard of care
Behavioral · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 10, 2026, 9:12 AM EDT
Completed Not applicable Interventional

Hypnosis for Symptom Management in Elective Orthopedic Surgery

NCT03308071
View directory record Official record
Conditions
Hypnosis, Perioperative Care, Knee Arthroplasty, Total, Postoperative Pain, Postoperative Complications
Interventions
Hypnosis
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 10, 2026, 9:12 AM EDT
Terminated Not applicable Interventional

Does Prehabilitation Improve Outcomes in Patients Undergoing Complex Spine Fusion Surgery?

NCT05034341
View directory record Official record
Conditions
Lumbar Spine Injury, Spinal Fusion, Frailty, Prehabilitation, Nutritional Supplementation, Functional Outcome
Interventions
Multimodal Prehabilitation, Standard Pre-Surgical Clinical Care
Other
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Oct 10, 2026, 9:12 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Assessing Pyridium for Post-Sling Urinary Retention

NCT03302936
View directory record Official record
Conditions
Urinary Retention
Interventions
Phenazopyridine
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 29, 2019 · Synced Oct 10, 2026, 9:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Goblet Cell Response and Dry Eye Symptoms After PRK and LASIK

NCT00411827
View directory record Official record
Conditions
Keratoconjunctivitis Sicca
Interventions
PRK with conjunctival impression cytology before and after surgery, LASIK with conjunctival impression cytology before and after surgery
Procedure
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
21 Years to 40 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 20, 2024 · Synced Oct 10, 2026, 9:12 AM EDT
Active, not recruiting Not applicable Interventional

A Study Comparing Mindfulness Apps to Decrease Anxiety in People With Lung Cancer

NCT06008574
View directory record Official record
Conditions
Lung Cancer
Interventions
AmDTx-PCSP, AmDTx-2048, Questionnaires
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 10, 2026, 9:12 AM EDT
Completed Not applicable Interventional

Role of Steroids and 10% Hypertonic Sodium Chloride in Adhesiolysis in Post Lumbar Surgery Syndrome Patients

NCT01053572
View directory record Official record
Conditions
Low Back Pain
Interventions
Adhesiolysis
Procedure
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Oct 10, 2026, 9:12 AM EDT
Completed Phase 4 Interventional Results available

Perioperative Insulin Glargine Dosing Study

NCT00309465
View directory record Official record
Conditions
Diabetes, Surgery
Interventions
Lantus, Insulin
Drug · Other
Lead sponsor
Tamra Dukatz
Other
Eligibility
18 Years and older
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
2
States / cities
Royal Oak, Michigan • Troy, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 3, 2012 · Synced Oct 10, 2026, 9:12 AM EDT
Recruiting Phase 4 Interventional

Methadone in the Management of Post-Operative Pain in Total Knee Replacement

NCT07485803
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Methadone
Drug
Lead sponsor
AdventHealth
Other
Eligibility
21 Years to 75 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 10, 2026, 9:12 AM EDT
Terminated Phase 4 Interventional Results available

Erector Spinae Plane Block (ESPB): in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.

NCT03691935
View directory record Official record
Conditions
Nephrectomy, Partial Nephrectomy, Incision Site Discomfort
Interventions
Ropivacaine, Normal saline
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 10, 2026, 9:12 AM EDT
Terminated Not applicable Interventional Results available

The Effect of Convective Pre-warming on Intra-operative Thermoregulatory Capabilities

NCT03876808
View directory record Official record
Conditions
Temperature Change, Body
Interventions
Bair Hugger™ Temperature Management Unit Model 750, 3M™ Bair Paws™ Flex Gown
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 2, 2023 · Synced Oct 10, 2026, 9:12 AM EDT
Completed Phase 3 Interventional

Nevanac 3-Month Safety Study With QID Dosing

NCT00332774
View directory record Official record
Conditions
Cataract
Interventions
Nepafenac ophthalmic solution 0.1%, Ketorolac Tromethamine ophthalmic solution 0.4%, Nepafenac ophthalmic suspension vehicle
Drug · Other
Lead sponsor
Alcon Research
Industry
Eligibility
10 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2012 · Synced Oct 10, 2026, 9:12 AM EDT
Active, not recruiting Not applicable Interventional

PREPARE: Patient Centered Perioperative Experience

NCT04472117
View directory record Official record
Conditions
Minimally Invasive Surgery (MIS) Hysterectomy
Interventions
usual care, Educational video
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
7
States / cities
Middletown, New Jersey • Montvale, New Jersey • Commack, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 10, 2026, 9:12 AM EDT
Completed Phase 2 Interventional Results available

S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery

NCT02562716
View directory record Official record
Conditions
Pancreatic Adenocarcinoma, Resectable Pancreatic Carcinoma
Interventions
Fluorouracil, Gemcitabine Hydrochloride, Irinotecan Hydrochloride, Oxaliplatin, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Pancreatectomy
Drug · Procedure
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
18 Years to 75 Years
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
807
States / cities
Birmingham, Alabama • Mobile, Alabama • Anchorage, Alaska + 515 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Oct 10, 2026, 9:12 AM EDT
Active, not recruiting Not applicable Interventional

PAtient-centered mUltidiSciplinary Care for vEterans Undergoing Surgery (PAUSE)

NCT05037292
View directory record Official record
Conditions
Frailty
Interventions
PAUSE Intervention
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
35,015 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Palo Alto, California • Nashville, Tennessee • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 10, 2026, 9:12 AM EDT
Recruiting Phase 4 Interventional

Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

NCT06962306
View directory record Official record
Conditions
Cleft Palate, Pain, Postoperative Care, Perioperative Care, Children
Interventions
Methadone hydrochloride, Fentanyl/Hydromorphone
Drug
Lead sponsor
Duke University
Other
Eligibility
6 Months to 4 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 10, 2026, 9:12 AM EDT