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ClinicalTrials.gov public records Last synced Nov 11, 2026, 11:40 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 169 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Peripheral Nerve Blockade Clear all

Conditions: Amputation, Phantom Limb Pain, Stump Pain
Interventions: perineural ropivicaine; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2017
U.S. locations: 1
States / cities: San Diego, California

Conditions: Peripheral Nerve Stimulation, Genicular Nerves, Chronic Knee Pain
Interventions: PNS therapy, Triamcinolone, Bupivacaine, Placebo; Other · Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Shoulder Surgery, Obesity
Interventions: Ultrasound-Guided Interscalene Brachial Plexus Block, Phrenic-Sparing Block Combination (Experimental), Bupivacaine HCl 0.5% Injectable Solution, Dexamethasone 4mg; Procedure · Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Rotator Cuff Injuries, Shoulder Disease, Hallux Valgus, Ankle Arthropathy
Interventions: Experimental Treatment; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Umbilical Hernia, Obesity
Interventions: TAPB Group, RSB Group, conversion to general anesthesia; Procedure
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 99 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Prostate CA
Interventions: Dexamethasone, TAP block; Drug · Procedure
Lead sponsor: Steward St. Elizabeth's Medical Center of Boston, Inc.; Other
Eligibility: 18 Years to 85 Years · Male only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Lower Extremity Surgery, Upper Extremity Surgery, Post-operative Pain
Interventions: Sciatic catheter left 0-1cm past needle tip vs. 5-6cm past needle tip; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: San Diego, California

Conditions: Surgery, Neuromuscular Blockade
Interventions: TetraGraph; Device
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 1 Month and older
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Ultrasound Imaging of Anatomical Structures
Interventions: Ultrasound scans; Device
Lead sponsor: IntelligentUltrasound Limited; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Continuous Femoral Nerve Blocks in Healthy Volunteers
Interventions: Catheter Anterior to the Femoral Nerve, Catheter Posterior to the Femoral Nerve; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: San Diego, California

Conditions: Injury of Anterior Cruciate Ligament
Interventions: bupivacaine, continuous perineural infusion catheter; Drug · Device
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 14 Years to 18 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: ACL, Anterior Cruciate Ligament Injuries
Interventions: Genicular Nerve Block with bupivacaine and preservative free dexamethasone; Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 80 Years
Enrollment: 192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Osteoarthritis of Hip, Regional Anesthesia, Other Acute Postoperative Pain, Total Hip Arthroplasty, Peripheral Nerve Block, Lumbar Plexus Nerve Block, Parasacaral (Sciatic) Nerve Block
Interventions: Continuous Lumbar Plexus Block, Parasacral Nerve Block, Ropivacine 0.2%, Bupivacaine 0.0625%; Procedure · Drug
Lead sponsor: Rita Merman; Other
Eligibility: 18 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Pain, Postoperative
Interventions: Single injection peripheral nerve block with liposomal bupivacaine (Exparel), Single injection peripheral nerve block with 0.25% bupivacaine and subsequent peripheral nerve catheter with 0.2% bupivacaine infusion via onQ pain pump; Procedure
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Surgery
Interventions: Tetragraph (TM) NMT Monitor; Device
Lead sponsor: Joseph D. Tobias; Other
Eligibility: 2 Years to 18 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Distal Radius Fracture
Interventions: Standardized Preoperative Education, Standard of care, Preoperative and postoperative questionnaires; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Pain, Postoperative, Cardiac Surgery
Interventions: PECS2 block, Ropivacaine 0.5% Injectable Solution, Lidocaine Epinephrine, Dexmedetomidine 0.004 MG/ML; Procedure · Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 19 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Mineola, New York

Conditions: Anesthesia, Local
Interventions: Survey; Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Stanford, California

Conditions: Lower Extremity Surgical Amputation, Post-amputation Phantom Limb Pain
Interventions: Experimental continuous peripheral nerve blocks, Control continuous peripheral nerve blocks; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2026
U.S. locations: 8
States / cities: San Diego, California • Boston, Massachusetts • Cleveland, Ohio + 1 more

Conditions: Chronic Pain
Interventions: Office-based procedure indicated for chronic pain with music, Office-based procedure indicated for chronic pain without music; Procedure
Lead sponsor: Lake Erie College of Osteopathic Medicine; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Wesley Chapel, Florida • Zephyrhills, Florida

Conditions: Ankle Block, Foot Surgery
Interventions: Mepivacaine, Bupivacaine; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Anesthesia
Interventions: Morphine Sulfate 150 mcg, Morphine Sulfate 50mcg; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: Female only
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Total Hip Arthroplasty, Postoperative Pain
Interventions: 0.1% or 0.2% ropivacaine nerve blocks; Drug
Lead sponsor: Sylvia Wilson; Other
Eligibility: 18 Years to 75 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Total Knee Arthroplasty, Pain, Postoperative, Adductor Canal Block
Interventions: Multimodal Peripheral Nerve Block Injection, Single Shot Adductor Canal Block, Initial Bolus, Continuous infusion; Procedure · Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 90 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Search by objective public record fields.

Prevention of Phantom Limb and Stump Pain Using Ambulatory Continuous Peripheral Nerve Blocks: A Pilot Study

Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study

Interscalene vs Phrenic-sparing Blocks in Obesity and Effect of Maximum Inspiratory Pressure

Feasibility of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery

Abdominal Wall Block Study

Evaluation of Addition of Dexamethasone to Transversus Abdominis Plane (TAP) Peripheral Nerve Block

Perineural Catheter Insertion Distance for Continuous Peripheral Nerve Blocks

TetraGraph to Evaluate Onset and Recovery Times of Rocuronium

A Study to Collect Imaging Data for the Validation of the Intelligent Ultrasound's ScanNav Anatomy Peripheral Nerve Block (PNB) - US v1.0

Effects of Catheter Tip Location Relative to the Femoral Nerve on Sensory and Motor Function

Opioid Use in Single Shot Nerve Block vs Continuous Peripheral Nerve Infusion in Anterior Cruciate Ligament (ACL) Repair

Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery

Continuous Lumbar Plexus Block With and Without Parasacral Block in Patients Undergoing Total Hip Replacement

Interscalene Catheter vs. Interscalene Liposomal Bupivacaine for Arthroscopic Rotator Cuff Repair

Train-of-four Monitoring Using the Tetragraph

Preoperative Education in Hand and Wrist Surgery

Pectoral Nerves Block to Relieve Post-sternotomy Pain After Cardiac Surgery

The CIA Score: a Learner's Tool

Improving Postamputation Functioning by Decreasing Phantom Pain With Perioperative Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study

Effects of Musical Intervention on Patient Pain and Anxiety for Office-based Procedures

Mepivacaine Versus Bupivacaine Onset Time in Ultrasound-guided Ankle Blocks

Decreased Neuraxial Morphine After Cesarean Delivery

A Comparison of Postoperative Analgesic Nerve Block Ropivacaine Concentrations

Single Injection Adductor Canal Block Versus Continuous Adductor Canal Infusion for Total Knee Arthroplasty