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ClinicalTrials.gov public records Last synced Nov 13, 2026, 6:07 AM EST

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Showing 145–168 of 169 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Peripheral Nerve Blockade Clear all

Conditions: Total Knee Arthroplasty
Interventions: Peripheral nerve blocks with Bupivacaine, Intra articular injection with Ropivacaine, Intra articular injection with liposomal bupivacaine; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Drop Foot
Interventions: Infiltration of papaverine, Lidocaine infiltration; Drug
Lead sponsor: US Neuropathy Centers; Other
Eligibility: Not listed
Enrollment: 4 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Jasper, Indiana

Conditions: Umbilical Hernia, Obesity
Interventions: TAPB Group, RSB Group, conversion to general anesthesia; Procedure
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 99 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Pain, Postoperative
Interventions: Proximal placement, Short axis ultrasound, Long axis, Distal placement; Procedure
Lead sponsor: VA Palo Alto Health Care System; Federal
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Pain, Shoulder Injury
Interventions: Preemptive Interscalene Block - Single Shot, Postoperative Interscalene Block- Single Shot, Preemptive Interscalene Block - Catheter, Postoperative Interscalene Block - Catheter; Procedure
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 10 Years to 21 Years
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2025
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Cardiogenic Shock
Interventions: Interscalene Block, PECS II Block, Superficial Cervical Plexus Block; Procedure
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 60 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Upper-extremity Surgery, Post-operative Pain
Interventions: Supraclavicular vs. Infraclavicular ropivicaine infusion; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: San Diego, California

Conditions: Hip Arthroplasty, Hip Pain
Interventions: Femoral Nerve Block vs. Psoas Compartment Nerve Block; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: San Diego, California

Conditions: Total Knee Arthroplasty, Pain, Postoperative, Adductor Canal Block
Interventions: Multimodal Peripheral Nerve Block Injection, Single Shot Adductor Canal Block, Initial Bolus, Continuous infusion; Procedure · Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 90 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Phantom Limb Pain
Interventions: Perineural infusion [continuous peripheral nerve block(s)]; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2020
U.S. locations: 4
States / cities: Palo Alto, California • San Diego, California • Bethesda, Maryland + 1 more

Conditions: Postsurgical Pain Management, Postsurgical Pain, Chronic, Opioid Use After Surgery
Interventions: TPS-Select, Pharmacologic Pain Management, Interventional Pain Procedures, Psychological Management and Pain Education, Physical Therapy; Device · Drug · Procedure + 1 more
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 474 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Phantom Limb Pain, Chronic Pain, Prevention
Interventions: Sciatic name block; Procedure
Lead sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pain
Interventions: Pre-operative Erector Spinae Plane block prior to DIEP surgery, Pre-operative Transversus Abdominus Plane blocks prior to DIEP surgery; Procedure
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Peripheral Nerve Block, Anxiety, Preoperative Anxiety
Interventions: Music, Midazolam; Other · Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Shoulder Pain
Interventions: interscalene nerve catheter; Device
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Postoperative Pain, Breast Cancer
Interventions: Paravertebral nerve block: 4 mL ropivacaine 0.5% at each of six levels, 10 cc of 0.375% ropivacaine pectoral nerve block; Drug
Lead sponsor: Timothy R Petersen; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Postoperative Mobility
Interventions: Proximal Brachial Plexus vs Distal Forearm Block; Procedure
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Osteoarthritis, Knee
Interventions: Dexamethasone, Bupivacaine, Epinephrine, Saphenous Peripheral Nerve Block; Drug · Procedure
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 90 Years
Enrollment: 85 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Lower Extremity Fracture, Surgical Fracture Repair, Orthopaedic Trauma, Orthogeriatric Fractures
Interventions: Local anesthesia injections; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 50 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Phantom Limb Pain
Interventions: Lower extremity amputation; Procedure
Lead sponsor: North Texas Veterans Healthcare System; Federal
Eligibility: 18 Years and older
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Pain, Postoperative, Total Knee Arthroplasty (TKA)
Interventions: Continuous Femoral Nerve Block, Nerve Block, Continuous Adductor Canal, Continuous Sciatic Nerve Block, Bupivacaine; Procedure · Drug
Lead sponsor: Kevin King, DO; Other
Eligibility: 18 Years to 75 Years
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Anesthesia
Interventions: Not listed
Lead sponsor: Defense and Veterans Center for Integrative Pain Management; Other
Eligibility: 18 Years to 89 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Lower Extremity Surgical Amputation, Post-amputation Phantom Limb Pain
Interventions: Experimental continuous peripheral nerve blocks, Control continuous peripheral nerve blocks; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2026
U.S. locations: 8
States / cities: San Diego, California • Boston, Massachusetts • Cleveland, Ohio + 1 more

Conditions: Shoulder Pain, Postoperative Pain
Interventions: Bupivacaine liposome, Bupivacaine Hydrochloride; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Search by objective public record fields.

Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)

The Investigators Are Comparing Lidocaine and Papaverine Nerve Blocks to Determine Which Improves Blood Flow Better, Making the "Phoenix Sign" Clearer on Imaging. This Helps Accurately Diagnose Nerve Compression, Improving Patient Care

Abdominal Wall Block Study

Optimizing Catheter Insertion Technique for Ultrasound-guided Continuous Peripheral Nerve Blocks

Efficacy of Nerve Blockade Performed Prior to Surgical Intervention Versus Following Surgical Intervention

Awake Axillary Impella 5.5 Placement - A Feasibility Trial

Optimization of Catheter Insertion Site for Continuous Peripheral Nerve Blocks

Femoral Versus Psoas Continuous Peripheral Nerve Blocks Following Hip Arthroplasty

Single Injection Adductor Canal Block Versus Continuous Adductor Canal Infusion for Total Knee Arthroplasty

Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study

An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service

Prevention of Phantom Limb Pain After Transtibial Amputation

ESPBs vs TAPs for Satisfactory Analgesia Following DIEP Surgery

Music vs Midazolam During Preop Nerve Block Placement - Part 2 Study On Anxiolytic Options Before Peripheral Nerve Blocks

A Study Comparing Two Methods of Placing an Interscalene Nerve Catheter for Postoperative Pain Control in Patients Who Undergo Open Shoulder Surgery.

Pectoral Nerve Blockade in Mastectomy

DBRCT on the Effect of Grip Strength in Brachial Plexus vs Distal Forearm Nerve Blocks

Perineural Steroids for Peripheral Nerve Blocks

Pre-Incision Peripheral Nerve Blocks for Lower Extremity Fracture Surgery in Older Adults

Incidence of Phantom Limb Pain and Method of Anesthesia After Lower Extremity Amputation

Continuous Adductor Canal Blocks Vs. Low Dose Femoral Nerve Blocks For Early Rehabilitation After Total Knee Arthroplasty

Study Measuring Total Plasma Ropivacaine Levels During Continuous Peripheral Nerve Catheter Infusion

Improving Postamputation Functioning by Decreasing Phantom Pain With Perioperative Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study

Interscalene Single Shot With Plain Bupivacaine Versus Liposomal Bupivacaine for Arthroscopic Shoulder Surgery