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ClinicalTrials.gov public records Last synced Oct 9, 2026, 3:04 AM EDT

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Showing 73–96 of 107 matching trials from the live ClinicalTrials.gov search.
Conditions
Amputation; Lower Extremity, Pain, Persistent Postsurgical
Interventions
Surgical Implantation
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
PTSD, Post Traumatic Stress Disorder PTSD, PTSD - Post Traumatic Stress Disorder, Post Traumatic Stress Disorder, Post Traumatic Stress Disorders, Post-traumatic Stress Disorder (PTSD), Post-Traumatic Stress Disorder, PTSD
Interventions
non-invasive vagus nerve stimulation
Device
Lead sponsor
Acacia Clinics
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sunnyvale, California
Conditions
Low Back Pain, Back Pain
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System, Standard interventional management of low back pain
Device · Procedure
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years to 75 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
18
States / cities
Little Rock, Arkansas • Walnut Creek, California • Greenwood Village, Colorado + 14 more
Conditions
Total Knee Replacement, Total Knee Arthroplasty, Pain, Postoperative Pain, Orthopedic Disorder
Interventions
SPRINT Beta System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years to 90 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
5
States / cities
La Jolla, California • Durham, North Carolina • Cleveland, Ohio + 2 more
Conditions
Chronic Knee Pain
Interventions
MiniStim PNS
Device
Lead sponsor
MiniStim LLC
Industry
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Lewisville, Texas
Completed Not applicable Interventional Results available

Peripheral Nerve Stimulation for Shoulder Pain: Dose Response

NCT02928055
Conditions
Stroke, Shoulder Pain
Interventions
Peripheral Nerve Stimulation
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 89 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Early Phase 1 Interventional Accepts healthy volunteers

Sevoflurane's Effect on Neurocognition Study

NCT06044740
Conditions
Anesthesia, Pain, Amnesia
Interventions
Sevoflurane, Peripheral Nerve Stimulation
Drug · Device
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years to 59 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Stroke
Interventions
PAS true, PAS sham
Behavioral
Lead sponsor
Burke Medical Research Institute
Other
Eligibility
19 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
White Plains, New York
Conditions
Rotator Cuff Tears, Shoulder Injuries, Hallux Valgus, Ankle Arthropathy, Clavicle Fracture
Interventions
Experimental Treatment, Sham Comparator
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Conditions
Knee Arthropathy
Interventions
Percutaneous peripheral nerve stimulation
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
La Jolla, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Regeneration of Acutely Injured Nerves With Temporary Electrical Stimulation

NCT05721261
Conditions
Nerve Injury
Interventions
Temporary Peripheral Nerve Stimulation System, Sham Temporary Peripheral Nerve Stimulation System
Device
Lead sponsor
Epineuron Technologies Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
6
States / cities
Gainesville, Florida • Orlando, Florida • New Orleans, Louisiana + 3 more
Conditions
Injury; Nerve, Peripheral, Multiple, Chronic Post-Procedural Pain, Total Knee Arthroplasty, Surgery, Knee Injuries, Knee Pain Chronic, Postoperative Pain, Chronic Postoperative Pain
Interventions
SPRINT® Peripheral Nerve Stimulation (PNS) System (510k Cleared)
Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Redwood City, California
Conditions
Stroke
Interventions
Peripheral nerve stimulation (PNS), Intensive upper extremity motor training
Device · Behavioral
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Peripheral Nerve Stimulation, Genicular Nerves, Chronic Knee Pain
Interventions
PNS therapy, Triamcinolone, Bupivacaine, Placebo
Other · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Conditions
Motor Function of Healthy Physiology
Interventions
TMS, tDCS, tACS, CPNS
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 120 Years
Enrollment
976 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Restless Legs Syndrome
Interventions
NTX100
Device
Lead sponsor
Noctrix Health, Inc.
Industry
Eligibility
21 Years and older
Enrollment
325 participants
Timeline
2023 – 2027
U.S. locations
7
States / cities
Downey, California • San Ramon, California • Newton, Massachusetts + 4 more
Conditions
Unilateral Carpal Tunnel Syndrome
Interventions
StimRouter System
Device
Lead sponsor
Bioness Inc
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Charleston, West Virginia
Conditions
Rotator Cuff Injuries, Shoulder Disease, Hallux Valgus, Ankle Arthropathy
Interventions
Experimental Treatment
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
La Jolla, California
Completed Not applicable Interventional Results available

Multimodal Treatment for Hemiplegic Shoulder Pain

NCT02893267
Conditions
Stroke, Shoulder Pain
Interventions
Peripheral Nerve Stimulation, Physical Therapy, Sham-PT, Sham-PNS
Device · Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 89 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
3
States / cities
Chicago, Illinois • Charlotte, North Carolina • Cleveland, Ohio
Withdrawn Not applicable Interventional Accepts healthy volunteers

Investigation of Embodiment for Upper Limb Amputees

NCT04578327
Conditions
Amputation
Interventions
Prosthetic hand, Peripheral Nerve Interface
Device · Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Thoracolumbar Compression Fractures
Interventions
SPRINT PNS modulation system
Device
Lead sponsor
Saint Peters University Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Avenel, New Jersey • Morganville, New Jersey • Somerset, New Jersey
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Rebuilding Inter-limb Transfer in Cervical SCI

NCT06440538
Conditions
Cervical Spinal Cord Injury
Interventions
PCMS + Contralateral Motor Training, PCMS + Rest, Sham PCMS + Contralateral Motor Training
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Restless Legs Syndrome
Interventions
Noninvasive Peripheral Nerve Stimulation (NPNS)
Device
Lead sponsor
Noctrix Health, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Downey, California • Dublin, Ohio
Not listed No phase listed Observational Accepts healthy volunteers

SPR PNS for Chronic Shoulder Pain

NCT05649917
Conditions
Shoulder Pain, Shoulder Injuries, Shoulder Arthritis
Interventions
Not listed
Lead sponsor
International Spine, Pain and Performance Center
Other
Eligibility
21 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Arlington, Virginia