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ClinicalTrials.gov public records Last synced Oct 4, 2026, 2:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 107 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Peripheral nerve stimulation (PNS) Clear all
Recruiting Not applicable Interventional

Exploring the Benefit of Peripheral Nerve Stimulation in Treating Pain From Chemo-induced Peripheral Neuropathy: A Longitudinal Single Center Feasibility Study

NCT06162403
View directory record Official record
Conditions
Peripheral Nerve Stimulation, Chemotherapy-induced Peripheral Neuropathy
Interventions
Peripheral Nerve Stimulation
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 4, 2026, 2:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biomarkers in Neural Disorders

NCT02761707
View directory record Official record
Conditions
Parkinson's Disease, Alzheimer's Disease, Progressive Supranuclear Palsy, Essential Tremor, Multiple System Atrophy, Drug Induced Parkinson's Disease, Diffuse Lewy Body Disease, Myasthenia Gravis, Spinal Cord Injuries
Interventions
Electrical Brainstem Responses, Olfactory Tests, Visual Deprivation, Peripheral Nerve Stimulation
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Oct 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Randomized Study of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery

NCT07052721
View directory record Official record
Conditions
Rotator Cuff Tears, Shoulder Injuries, Hallux Valgus, Ankle Arthropathy, Clavicle Fracture
Interventions
Experimental Treatment, Sham Comparator
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 4, 2026, 2:19 AM EDT
Not yet recruiting Not applicable Interventional

Hypersound Treatment for Chronic Neuropathic and Radicular Pain

NCT07831447
View directory record Official record
Conditions
Chronic Neuropathic Pain, Radiculopathy, Sciatica, Peripheral Neuropathic Pain
Interventions
Hypersound RF-PNS system, Sham Hypersound
Device
Lead sponsor
Hypersound Medical Inc
Industry
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 4, 2026, 2:19 AM EDT
Completed Phase 4 Interventional Results available

Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145)

NCT03346057
View directory record Official record
Conditions
Reversal of Neuromuscular Blockade
Interventions
Sugammadex 2 mg/kg, Sugammadex 4 mg/kg, Sugammadex 16 mg/kg, Neostigmine + Glycopyrrolate, Rocuronium, Vecuronium
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years and older
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
20
States / cities
Birmingham, Alabama • Tucson, Arizona • Loma Linda, California + 15 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 4, 2026, 2:19 AM EDT
Completed Phase 1 Interventional

Traumatic Brain Injury Peripheral Nerve Study

NCT01588691
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Eon-mini IPG (implantable pulse generator)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Poway, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation for the Treatment of Post-Amputation Pain Using the SPRINT System

NCT01996254
View directory record Official record
Conditions
Post-Amputation Pain, Phantom Limb Pain, Residual Limb Pain
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
10
States / cities
Scottsdale, Arizona • La Jolla, California • Denver, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Oct 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Multicenter Continuous Peripheral Nerve Block Surveillance Study

NCT00653133
View directory record Official record
Conditions
Postoperative Pain
Interventions
Ultrasound imaging, Peripheral nerve stimulator
Device
Lead sponsor
Halyard Health
Industry
Eligibility
18 Years and older
Enrollment
1,821 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
16
States / cities
Chandler, Arizona • San Jose, California • Louisville, Colorado + 13 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2018 · Synced Oct 4, 2026, 2:19 AM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Dose-finding Study of Selective Serotonin Reuptake Inhibitors to Enhance Neuroplasticity

NCT04221256
View directory record Official record
Conditions
Stroke, Ischemic
Interventions
Administration of SSRI escitalopram, Paired Associative stimulation, Administration of Placebo
Drug · Behavioral
Lead sponsor
Burke Medical Research Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2021 · Synced Oct 4, 2026, 2:19 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Neural Operant Conditioning

NCT06113965
View directory record Official record
Conditions
Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic, Walking, Difficulty
Interventions
Peripheral Nerve Stimulation
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 4, 2026, 2:19 AM EDT
Not listed Not applicable Interventional

Clinical Trial of the MiniStim PNS for Knee Pain- "FLEX" Study

NCT04580732
View directory record Official record
Conditions
Chronic Knee Pain
Interventions
MiniStim PNS
Device
Lead sponsor
MiniStim LLC
Industry
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Lewisville, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2023 · Synced Oct 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wearable Focused Ultrasound Stimulation for Peripheral Nerve Pain Management

NCT07160049
View directory record Official record
Conditions
Pain Management, Peripheral Neuropathic Pain
Interventions
Cold Pressor Task - Upper Limb, Algometry Pain Tests in the Upper Limb, Algometry Pain Tests in the Lower Limb
Device
Lead sponsor
Evan (Huiliang) Wang
Other
Eligibility
20 Years to 40 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Physiological Investigations of Movement Disorders

NCT01019343
View directory record Official record
Conditions
Parkinson's Disease, Tourette's Syndrome, Tic Disorders, Dystonia, Movement Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Eye-tracking Device, Pulsed vibrator, Gait Trainer Treadmill (GTT), Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA, iMobility, QMAT, Treadmill Test, Arm Intellistretch Device, Transcranial Sonography (TCS), Behavioral tasks, TMS single/paired pulse, MEG, EEG, MRI techniques, Peripheral Nerve Stimulation, EMG, Trancutaneous spinal direct current stimulation (tsDCS)
Procedure · Device · Other + 1 more
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
1,273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 4, 2026, 2:19 AM EDT
Recruiting Phase 3 Interventional

Mechanisms of Stimulation for Pain Alleviation

NCT06741579
View directory record Official record
Conditions
Peripheral Nerve Stimulation, Chronic Neuropathic Pain, Chronic Neuropathic Pain (Below the Shoulders)
Interventions
Peripheral Nerve Stimulation, Conventional Care Regimen
Device · Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Palo Alto, California • Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 4, 2026, 2:19 AM EDT
Recruiting Not applicable Interventional

Uncovering the Mechanism of Pain Relief by Peripheral Transcutaneous Magnetic Stimulation

NCT07199361
View directory record Official record
Conditions
Post-Surgical Pain, Chronic, Post-traumatic Pain, Chronic
Interventions
Peripheral Transcutaneous Magnetic Stimulation from MagVenture
Device
Lead sponsor
Florida International University
Other
Eligibility
19 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 4, 2026, 2:19 AM EDT
Terminated Not applicable Interventional

Activity-Dependent Transspinal Stimulation in SCI

NCT03669302
View directory record Official record
Conditions
Spinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, Spastic
Interventions
Robotic gait training, Robotic gait training and low-frequency transspinal stimulation, Robotic gait training and high-frequency transspinal stimulation
Other · Device
Lead sponsor
City University of New York
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Staten Island, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2022 · Synced Oct 4, 2026, 2:19 AM EDT
Active, not recruiting No phase listed Observational

Retrospective PNS Study

NCT06832449
View directory record Official record
Conditions
Chronic Pain
Interventions
PNS
Device
Lead sponsor
Curonix LLC
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Oct 4, 2026, 2:19 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Neural Correlates of Lidocaine Analgesia

NCT05501600
View directory record Official record
Conditions
Anesthesia, Pain
Interventions
Peripheral Nerve Stimulation, Lidocaine IV
Device · Drug
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 24, 2024 · Synced Oct 4, 2026, 2:19 AM EDT
Recruiting Not applicable Interventional

Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study

NCT06004882
View directory record Official record
Conditions
Peripheral Nerve Stimulation, Genicular Nerves, Chronic Knee Pain
Interventions
PNS therapy, Triamcinolone, Bupivacaine, Placebo
Other · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 4, 2026, 2:19 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Paired Stimulation Plasticity for Motor Recovery in Humans With and Without Spinal Cord Injury

NCT07814313
View directory record Official record
Conditions
Healthy Control, Spinal Cord Injury
Interventions
CST PAS, RST PAS, sham PAS
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
19 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 4, 2026, 2:19 AM EDT
Withdrawn Not applicable Interventional

Feasibility of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Knee Surgery

NCT07336355
View directory record Official record
Conditions
Knee Arthropathy
Interventions
Percutaneous peripheral nerve stimulation
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 4, 2026, 2:19 AM EDT
Not yet recruiting Not applicable Interventional

Altius Peripheral Nerve Stimulation in Amputees After TMR/RPNI

NCT07571239
View directory record Official record
Conditions
Amputation; Lower Extremity, Pain, Persistent Postsurgical
Interventions
Surgical Implantation
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 4, 2026, 2:19 AM EDT
Active, not recruiting Not applicable Interventional

The MONARCH Case Series Study: SPRINT® Peripheral Nerve Stimulation for the Treatment of Head Pain

NCT05491915
View directory record Official record
Conditions
Cervicogenic Headache, Occipital Neuralgia
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
10
States / cities
Santa Rosa, California • Waltham, Massachusetts • Rochester, Minnesota + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 4, 2026, 2:19 AM EDT
Not listed No phase listed Observational

Treatment of Shoulder Osteoarthritis

NCT05657587
View directory record Official record
Conditions
Chronic Shoulder Pain
Interventions
SPRINT PNS
Device
Lead sponsor
Gramercy Pain Center
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Holmdel, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 27, 2023 · Synced Oct 4, 2026, 2:19 AM EDT