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ClinicalTrials.gov public records Last synced Oct 18, 2026, 5:59 AM EDT

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Showing 1–24 of 73 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Phacoemulsification Clear all
Completed Not applicable Interventional Results available

Clareon Toric vs Eyhance Toric

NCT05481125
View directory record Official record
Conditions
Cataract, Aphakia
Interventions
Clareon IOL, Clareon Toric IOL, Eyhance IOL, Eyhance Toric IOL, Phacoemulsification surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
8
States / cities
Poughkeepsie, New York • Brecksville, Ohio • Mt. Pleasant, South Carolina + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2024 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Tetracaine 0.5% and Lidocaine 2% Jelly for Topical Phacoemulsification Cataract Surgery

NCT00827073
View directory record Official record
Conditions
Cataracts
Interventions
tetracaine 0.5%, Lidocaine 2% Jelly
Drug
Lead sponsor
Hermann Eye Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 22, 2014 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Not applicable Interventional

Post Market Clinical Evaluation of Clareon PanOptix Pro and Clareon PanOptix Pro Toric IOLs

NCT07161635
View directory record Official record
Conditions
Aphakia, Presbyopia
Interventions
Clareon PanOptix Pro/Pro Toric Trifocal IOL, Phacoemulsification
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
5
States / cities
Torrance, California • Kansas City, Missouri • Mt. Pleasant, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 18, 2026, 5:59 AM EDT
Completed No phase listed Observational

Comparison of Femtosecond Laser Assisted Cataract Surgery to Conventional Phacoemulsification Cataract Surgery

NCT02096627
View directory record Official record
Conditions
Cataract
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 16, 2018 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification

NCT01454063
View directory record Official record
Conditions
Intraocular Lens Replacement
Interventions
OMS302, Placebo
Drug
Lead sponsor
Omeros Corporation
Industry
Eligibility
18 Years and older
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
16
States / cities
Chandler, Arizona • Glendale, Arizona • Los Angeles, California + 13 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2014 · Synced Oct 18, 2026, 5:59 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

A Prospective Multicenter Study To Assess The Clinical Outcomes Of Current Phacoemulsification Approach To Cataract Extraction Versus The Micor System Device

NCT05729477
View directory record Official record
Conditions
Cataract Surgery
Interventions
miCOR System, Phaco Subject Cohort
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
18 Years and older
Enrollment
402 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
6
States / cities
Cape Coral, Florida • West Palm Beach, Florida • Hiawatha, Iowa + 3 more
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Phase 4 Interventional Results available

Dropless vs. Standard Drops Contralateral Eye Study

NCT02515045
View directory record Official record
Conditions
Cataract
Interventions
TriMoxiVanc, Moxifloxacin HCl 0.5%, Ilevro, Prednisolone acetate 1%
Drug
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years to 80 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
4
States / cities
Bloomington, Minnesota • Stillwater, Minnesota • Garden City, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2018 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Not applicable Interventional Results available

Conventional Surgery vs. Verion/VerifEye

NCT02513745
View directory record Official record
Conditions
Cataract, Astigmatism
Interventions
Conventional, Refractive Cataract Suite (Verion + ORA)
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 4, 2019 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Not applicable Interventional

Intraocular Pressure Control Following One Site Versus Two Site Combined Phacoemulsification/IOL And Trabeculectomy

NCT00695747
View directory record Official record
Conditions
Glaucoma, Cataracts
Interventions
2 Site procedure- Phacoemulsification/IOL and Trabeculectomy
Procedure
Lead sponsor
Lahey Clinic
Other
Eligibility
Not listed
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2009
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 22, 2009 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Not applicable Interventional

Resident-Performed Laser-Assisted vs Manual Traditional Phacoemulsification Cataract Surgery

NCT02561104
View directory record Official record
Conditions
Incipient Cataract, Senile Nuclear Sclerosis
Interventions
Laser-assisted cataract surgery., Traditional manual phacoemulsification
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 99 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Oct 18, 2026, 5:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Physiologic Phacofluidics: Ghost Protocol

NCT06904404
View directory record Official record
Conditions
Cataract
Interventions
Cataract surgery at high IOP, Cataract surgery at low IOP
Procedure
Lead sponsor
Wolfe Eye Clinic
Other
Eligibility
55 Years to 95 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Hiawatha, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Not applicable Interventional Results available

Randomized Contralateral Clinical Trial With Single-piece (SN60WF) vs. Three Piece (MA60AC) AcrySof Intraocular Lenses (IOLs) on Development of Posterior Chamber Opacification (PCO).

NCT00758745
View directory record Official record
Conditions
Cataract
Interventions
Model SN60WF, Model MA60AC
Device
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2014 · Synced Oct 18, 2026, 5:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Phacoemulsification at High IOP and Physiologic IOP: Impact on Anterior and Posterior Segment Physiology

NCT05765201
View directory record Official record
Conditions
Nuclear Cataract
Interventions
High IOP, Low IOP
Other
Lead sponsor
Matthew Rauen
Other
Eligibility
Not listed
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
West Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 8, 2024 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Comparison of Prophylactic Antibacterial Efficacy of Besivance vs. VIGAMOX Prior to Cataract Surgery

NCT01296542
View directory record Official record
Conditions
Cataracts
Interventions
Moxifloxacin Ophthalmic, Besifloxacin Ophthalmic
Drug
Lead sponsor
Bucci Laser Vision Institute
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 8, 2020 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Phase 3 Interventional Results available

Safety, Efficacy and Pharmacokinetics of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification

NCT01579565
View directory record Official record
Conditions
Intraocular Lens Replacement
Interventions
OMS302, Placebo
Drug
Lead sponsor
Omeros Corporation
Industry
Eligibility
18 Years and older
Enrollment
416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
13
States / cities
Chandler, Arizona • Los Angeles, California • Fort Myers, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2017 · Synced Oct 18, 2026, 5:59 AM EDT
Recruiting No phase listed Observational

Effective Phaco Time and Endothelial Cell Loss When Using Veritas

NCT07176416
View directory record Official record
Conditions
Cataract
Interventions
Veritas Vision System
Device
Lead sponsor
Aloha Vision Consultants
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
‘Aiea, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Steroid vs. Anti-vascular Endothelial Growth Factor for Diabetic Macular Edema Prior to Phacoemulsification

NCT03832179
View directory record Official record
Conditions
Diabetic Macular Edema, Cataract
Interventions
Bevacizumab, Ranibizumab, Aflibercept, Ozurdex
Drug
Lead sponsor
Bay Area Retina Associates
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Walnut Creek, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 18, 2026, 5:59 AM EDT
Recruiting Not applicable Interventional

Hydrus® Microstent New Enrollment Post-Approval Study

NCT04553523
View directory record Official record
Conditions
Primary Open Angle Glaucoma
Interventions
Hydrus Microstent, Cataract surgery, Monofocal IOL
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
45 Years and older
Enrollment
545 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
22
States / cities
Irvine, California • Sacramento, California • Loveland, Colorado + 19 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 18, 2026, 5:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Less Discomfort and Less Pharmacology. Cataract Surgery at Physiologic Intraocular Pressure (IOP)

NCT06325397
View directory record Official record
Conditions
Nuclear Cataract
Interventions
High Intraocular Pressure (IOP), Low Intraocular Pressure (IOP)
Other
Lead sponsor
Matthew Rauen
Other
Eligibility
Not listed
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
West Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of the Next Generation Phaco System

NCT04332640
View directory record Official record
Conditions
Cataract
Interventions
VERITAS Vision System
Device
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
22 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Phase 1Phase 2 Interventional

Exploratory Study of OMS302 Injection in Subjects Undergoing Unilateral Cataract Extraction by Phacoemulsification.

NCT00721695
View directory record Official record
Conditions
Cataract Extraction
Interventions
OMS302, OMS302-PE, Vehicle
Drug
Lead sponsor
Omeros Corporation
Industry
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
4
States / cities
Redding, California • Bloomington, Minnesota • Kansas City, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2014 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment of Low Energy Lens Fragmentation Cataract Extraction in Patients Undergoing Cataract Surgery

NCT04747834
View directory record Official record
Conditions
Cataract
Interventions
MICOR-304
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
3
States / cities
Vestavia Hills, Alabama • Cape Coral, Florida • Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Oct 18, 2026, 5:59 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Aqueous Absorption and Pharmacokinetics of Besivance Versus VIGAMOX in Patients Undergoing Phacoemulsification

NCT01296191
View directory record Official record
Conditions
Cataracts
Interventions
Moxifloxacin, besifloxacin
Drug
Lead sponsor
Frank A. Bucci, Jr., M.D.
Other
Eligibility
18 Years to 100 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 22, 2020 · Synced Oct 18, 2026, 5:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Venturi and Peristaltic Based Phacoemulsification in Femtosecond Laser Cataract Surgery

NCT03970525
View directory record Official record
Conditions
Cataract Senile
Interventions
Venturi pump, Peristaltic vacuum pump
Device
Lead sponsor
Wendell Scott
Other
Eligibility
22 Years to 90 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Oct 18, 2026, 5:59 AM EDT