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Showing 1–18 of 18 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Pharyngeal Manometry Clear all
Completed No phase listed Observational Accepts healthy volunteers

Use of High-resolution Manometry to Detect Upper Airway Obstruction During Sleep

NCT04139499
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Drug-induced sleep endoscopy (DISE), High-resolution manometry (HRM):
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
5 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Sep 10, 2026, 2:32 AM EDT
Terminated No phase listed Observational

Effects of Oral Cancer Treatments on Upper Esophageal Opening During Swallowing

NCT04658342
View directory record Official record
Conditions
Cancer of Head and Neck
Interventions
Videofluoroscopic imaging (VFSS) with high-resolution manometry (HRM)
Diagnostic Test
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Sep 10, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mechanisms Preventing Pharyngeal Reflux

NCT05696184
View directory record Official record
Conditions
GERD
Interventions
Concurrent manometry/impedance/pH with video pharyngo-laryngoscopy, Slow and rapid intra-esophageal infusion
Diagnostic Test
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 10, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Striated Esophageal Motor Function Modulation in Health and Disease

NCT05708885
View directory record Official record
Conditions
Dysphagia, Esophageal
Interventions
Concurrent manometry/impedance and fluoroscopy with and without laryngeal restriction, Concurrent manometry/impedance and fluoroscopy before and after six weeks of using swallow muscle exercising device
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 90 Years
Enrollment
557 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 10, 2026, 2:32 AM EDT
Withdrawn No phase listed Observational

Simultaneous Fluoroscopic and Manometric Measures of the Oropharyngeal Phase of Deglutition

NCT00584545
View directory record Official record
Conditions
Dysphagia
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Sep 10, 2026, 2:32 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effects of an Air Bolus on Primary Peristalsis

NCT06465355
View directory record Official record
Conditions
Deglutition Disorders
Interventions
pharyngo-esophageal high-resolution manometry
Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
21 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Sep 10, 2026, 2:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Rehabilitation Manometry Study

NCT04130867
View directory record Official record
Conditions
Oropharyngeal Dysphagia
Interventions
pHRM, VFSS
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 99 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Sep 10, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional

DISE: Phenotyping Obstruction Patterns

NCT05050383
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Pharyngeal Manometry, Submental Ultrasound
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Sep 10, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Pharyngeal Metrics to Predict Dysphagia Outcomes

NCT04569097
View directory record Official record
Conditions
Dysphagia, Swallowing Disorders
Interventions
standard of care lingual strengthening
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
3
States / cities
Hines, Illinois • Cincinnati, Ohio • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 10, 2026, 2:32 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Standardizing Swallow Pressure Measurements

NCT07475091
View directory record Official record
Conditions
Dysphagia
Interventions
Laborie LMT Pharyngeal System (3.7 mm catheter), Medtronic ManoScan ESO HRM System (4.2 mm catheter)
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 99 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 10, 2026, 2:32 AM EDT
Completed Not applicable Interventional

Pharyngeal Anatomy In Obstructive Sleep Apnea With HRM

NCT03198416
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
High-resolution pharyngeal manometry catheter
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 25, 2024 · Synced Sep 10, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

External Pharyngeal Exerciser and Pharyngeal Phase of Swallowing

NCT05708911
View directory record Official record
Conditions
Dysphagia
Interventions
Pharyngeal exerciser
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 10, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

High Resolution Pharyngeal Manometry (HRPM) Biofeedback

NCT07508059
View directory record Official record
Conditions
Healthy
Interventions
Swallowing Maneuvers, High Resolution Pharyngeal Manometry (HRPM)
Other · Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 10, 2026, 2:32 AM EDT
Enrolling by invitation Not applicable Interventional

Myofunctional Therapy for Obstructive Sleep Apnea

NCT07301125
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Myofunctional Therapy
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 10, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Swallowing Pressure Profiles in Healthy Adults

NCT03986554
View directory record Official record
Conditions
Healthy
Interventions
Videofluoroscopic swallow study, pharyngeal High Resolution Manometry
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 45 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 16, 2020 · Synced Sep 10, 2026, 2:32 AM EDT
Withdrawn Not applicable Interventional

Role of Pharyngeal High Resolution Manometry and Impedance in Swallow Function of Head and Neck Cancer Patients

NCT03372148
View directory record Official record
Conditions
Head and Neck Cancer, Dysphagia
Interventions
pHRMi
Diagnostic Test
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
2
States / cities
Baltimore, Maryland • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 10, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study: Manometry With & Without Lidocaine

NCT03349112
View directory record Official record
Conditions
Normal
Interventions
4% Lidocaine Spray, 2% Viscous Lidocaine
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Sep 10, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Upper Airway Obstruction

NCT04322097
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Hypoglossal Nerve Stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years and older
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 10, 2026, 2:32 AM EDT