- Conditions
- Obstructive Sleep Apnea
- Interventions
- Negative Pressure Ventilator, Pulmonary Function Testing (PFT), Transcutaneous Phrenic Nerve Stimulation, Percutaneous Phrenic Nerve Stimulation
- Device
- Lead sponsor
- Emory University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 151 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
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- Conditions
- Sleep Apnea, Central, Heart Failure
- Interventions
- Phrenic nerve stimulator
- Device
- Lead sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
- Other
- Eligibility
- 18 Years to 85 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Brighton, Massachusetts
- Conditions
- Ventilator Induced Diaphragm Dysfunction
- Interventions
- Lungpacer DPTS (Diaphragm Pacing Therapy System)
- Device
- Lead sponsor
- Lungpacer Medical Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 4
- States / cities
- Gainesville, Florida • New York, New York • Philadelphia, Pennsylvania + 1 more
- Conditions
- Amyotrophic Lateral Sclerosis (ALS)
- Interventions
- NeuRx Diaphragm Pacing System (DPS)
- Device
- Lead sponsor
- Synapse Biomedical
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 97 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2017
- U.S. locations
- 11
- States / cities
- Los Angeles, California • San Francisco, California • Denver, Colorado + 8 more
- Conditions
- Sepsis
- Interventions
- Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP), Inspiratory Muscle Strength Training (IMST), SHAM Inspiratory Muscle Strength Training (IMST), Diaphragm thickness measurement, Blood and Urine samples
- Procedure · Drug · Device + 1 more
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- Gainesville, Florida