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ClinicalTrials.gov public records Last synced Oct 12, 2026, 3:40 AM EDT

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Showing 121–144 of 748 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Physical activity and dietary change Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks

NCT05674799
View directory record Official record
Conditions
Overweight or Obesity
Interventions
NDPP-NextGen
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 39 Years · Female only
Enrollment
403 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Team PLAY (Positive Lifestyles for Active Youngsters)

NCT00528164
View directory record Official record
Conditions
Obesity
Interventions
Team PLAY
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
4 Years to 7 Years
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 18, 2013 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional

A Mail and Video-based Weight Loss Trial in Breast Cancer Survivors

NCT02681965
View directory record Official record
Conditions
Breast Cancer Survivorship, Obesity
Interventions
LEAN book/videos
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 79 Years · Female only
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 29, 2018 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aging, Lifestyle and Inflammation in Veterans Exercising

NCT00667030
View directory record Official record
Conditions
Inflammation, Aging, Metabolism, Exercise
Interventions
Weight loss and aerobic exercise training
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Phase 4 Interventional Results available

A Toolbox Approach to Obesity Treatment in Primary Care

NCT01922934
View directory record Official record
Conditions
Obesity
Interventions
Commercial weight loss program, Colorado Weigh, Meal replacements, Obesity pharmacotherapy, Recreation center passes
Behavioral · Dietary Supplement · Drug
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 80 Years
Enrollment
4,730 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 18, 2017 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Comprehensive Lifestyle Improvement Program for Men With Prostate Cancer

NCT04000464
View directory record Official record
Conditions
Prostate Cancer
Interventions
CLIPP
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
40 Years to 89 Years · Male only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 14, 2020 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alternate Day Fasting, Exercise, and NAFLD

NCT04004403
View directory record Official record
Conditions
Non-Alcoholic Fatty Liver Disease, Obesity
Interventions
Alternate day fasting, Exercise
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Oct 12, 2026, 3:40 AM EDT
Recruiting Not applicable Interventional

Integrating a Prescription Produce Program Within a Diabetes Prevention Program

NCT07472712
View directory record Official record
Conditions
Prediabetes
Interventions
Diabetes Prevention Program (DPP), Produce Prescription Plan (PPP)
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Giving a Low Carbohydrate Diet to Overcome Hypertension

NCT04230928
View directory record Official record
Conditions
Hypertension, African Americans, Diet, Carbohydrate-Restricted, Risk Reduction Behavior
Interventions
Very low carbohydrate diet, Standard DPP-GLB diet, Standard DPP-GLB program modules
Other · Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 74 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Social Media Obesity Treatment for College Students

NCT02342912
View directory record Official record
Conditions
Obesity
Interventions
Social Media Treatments
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 35 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes

NCT01073020
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Allergan Adjustable Gastric Band Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Band Group, Roux-en-Y Gastric Bypass (RYGB) Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Bypass Group
Device · Other · Procedure
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
21 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Chest Pain Observation Unit Risk Reduction Trial

NCT00536224
View directory record Official record
Conditions
Chest Pain
Interventions
Full counseling, Minimal counseling
Behavioral
Lead sponsor
David A Katz
Other
Eligibility
30 Years to 100 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 26, 2018 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Diet and Exercise Intervention in Type 2 Diabetes

NCT01977560
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Intensive Lifestyle Intervention, Standard Care
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
25 Years to 68 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 15, 2022 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maternal Health Diabetes Prevention Study

NCT05343494
View directory record Official record
Conditions
Gestational Diabetes, PreDiabetes, Hyperglycemia, Glucose Intolerance During Pregnancy
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 30, 2022 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Active You: Walk, Dance, and Tone Your Abs to Reduce Your Risk of Diabetes

NCT06127251
View directory record Official record
Conditions
Obesity
Interventions
PATH Intervention, Control Group, Physical activity tracker, Dietary education
Behavioral · Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Study of an International Commercial Program on Weight Loss and Health Outcomes

NCT03571893
View directory record Official record
Conditions
Weight Loss, Weight Change, Body, Obesity, Diet Modification
Interventions
Weight Watchers Freestyle (Flex), DIY Personal Plan
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
373 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

TAME Health: Testing Activity Monitors' Effect on Health

NCT02554435
View directory record Official record
Conditions
Physical Activity
Interventions
EAM, 5 A's counseling, Pedometer
Device · Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
55 Years to 74 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
2
States / cities
Galveston, Texas • League City, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Dietary and Exercise Interventions in Reducing Side Effects in Patients With Stage I-IIIa Breast Cancer Receiving Aromatase Inhibitors

NCT03953157
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Arthralgia, Postmenopausal, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8
Interventions
Dietary Intervention, Exercise Intervention, Questionnaire Administration
Dietary Supplement · Behavioral · Other
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Phase 2 Interventional

Interventions to Improve Hypertension Control and Reduce Cardiovascular Disease Risk

NCT00201136
View directory record Official record
Conditions
Hypertension
Interventions
Lifestyle interventions to lower blood pressure for patients, MD CQI-type intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
25 Years and older
Enrollment
574 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 14, 2015 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

ELIRA 2: Safety and Effectiveness of TENS Assisted Weight Loss and Appetite Suppression

NCT03936699
View directory record Official record
Conditions
Weight Loss
Interventions
Transcutaneous Nerve Stimulator (TENS), Diet & Exercise
Device · Behavioral
Lead sponsor
Elira Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parent Supported Weight Reduction in Down Syndrome

NCT01256112
View directory record Official record
Conditions
Down Syndrome
Interventions
Parent Supported Behavioral Intervention, Nutrition/Activity Education (NAE)
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
13 Years to 26 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Oct 12, 2026, 3:40 AM EDT
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects

NCT05653258
View directory record Official record
Conditions
Obesity, Healthy Lifestyle
Interventions
Lifestyle Intervention, Dasatinib 100 MG, Quercetin 1000mg, Placebo, Abdominal adipose tissue biopsy
Other · Drug · Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 12, 2026, 3:40 AM EDT
Not listed Not applicable Interventional

RYSE Family-based Behavioral Treatment for Childhood Obesity

NCT05212155
View directory record Official record
Conditions
Obesity, Childhood
Interventions
family-based behavioral treatment (FBT)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
5 Years to 12 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Joplin, Missouri • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 12, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

TRUST Study of Adolescent Weight Self-Management

NCT03016247
View directory record Official record
Conditions
Adolescent Obesity
Interventions
TRUST Intervention, Enhanced Usual Care
Behavioral
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
10 Years to 12 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 2, 2019 · Synced Oct 12, 2026, 3:40 AM EDT