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These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 2, 2026, 3:21 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–38 of 38 matching trials from the live ClinicalTrials.gov search.

Conditions: PSP, CBD, PCA, LPA, Semantic Dementia, Semantic Aphasia, Behavioral Variant of Frontotemporal Dementia, FTD, PPA, Apraxia of Speech, MSA - Multiple System Atrophy, Parkinson Disease
Interventions: C-11 PiB, AV1451 Tau, C-11 ER176; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 21 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2050
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Alzheimer's Disease, Dementia With Lewy Bodies, Frontotemporal Dementia, Vascular Dementia
Interventions: Pittsburgh Compound B (C-11 PiB), F-18 FDG, Tau (18-F-AV-1451); Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 30 Years to 100 Years
Enrollment: 8,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2027
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Concussion, Brain
Interventions: [11C] PiB, [18F] PBR111, [18F] Flortaucipir; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 50 Years to 70 Years · Male only
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2028
U.S. locations: 3
States / cities: Waltham, Massachusetts • Chapel Hill, North Carolina • Milwaukee, Wisconsin

Conditions: Dementia
Interventions: 11C-ER176, 11C-PIB, Positron Emission Tomography (PET) Scan; Drug · Diagnostic Test
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 18 Years and older
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Multiple Sclerosis, Inflammatory Demyelinating Disease
Interventions: C-11 ER176 Radiotracer, C11 Pittsburgh Compound B, PET/CT scan, MRI; Drug · Diagnostic Test
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Atypical Alzheimer's Disease, Logopenic Progressive Aphasia (LPA), Posterior Cortical Atrophy (PCA), Alzheimer Disease, Alzheimer Disease, Early Onset, Amnestic Disorder, Amnestic Symptoms, Amnestic Mild Cognitive Disorder
Interventions: F-18 AV 1451, C-11 PiB; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 21 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Alzheimer Disease
Interventions: 18F-Flortaucipir radiopharmaceutical, 18F-MK-6240 radiopharmaceutical, Amyloid-β radiopharmaceutical (11C-PiB or 18F-Florbetaben or 18F-NAV-4694 or 18F-Flutemetamol); Drug
Lead sponsor: Tharick Pascoal; Other
Eligibility: 18 Years to 90 Years
Enrollment: 822 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 7
States / cities: Berkeley, California • San Francisco, California • Rochester, Minnesota + 4 more

Conditions: PPA, Primary Progressive Aphasia, Aphasia, Non-fluent Aphasia, Semantic Dementia, Apraxia of Speech, Primary Progressive Nonfluent Aphasia, Progressive Aphasia
Interventions: C-11 PiB, F-18 FDG; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Rochester, Minnesota

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