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ClinicalTrials.gov public records Last synced Oct 10, 2026, 8:24 PM EDT

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Showing 73–96 of 146 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Placebo Capsule + Placebo Beverage Clear all
Completed Phase 2 Interventional Results available

Polyunsaturated Fatty Acids (PUFA) in Diabetic Fatty Liver

NCT00323414
View directory record Official record
Conditions
Fatty Liver
Interventions
Polyunsaturated fatty acid (Opti-EPA), Placebo
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 23, 2018 · Synced Oct 10, 2026, 8:24 PM EDT
Not listed Not applicable Interventional

Assess the Effects of a Limosilactobacillus Supplement on Recurrence of UTI in Healthy Women During a 6-month Period

NCT05793814
View directory record Official record
Conditions
Uncomplicated Symptomatic Urinary Tract Infections
Interventions
Limosilactobacillus reuteri 3613, Placebo
Dietary Supplement
Lead sponsor
Church & Dwight Company, Inc.
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 31, 2023 · Synced Oct 10, 2026, 8:24 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Dry Eye Assessment and Management: Feasibility Study

NCT01102257
View directory record Official record
Conditions
Dry Eye Syndromes, Keratoconjunctivitis Sicca
Interventions
Omega-3 EFA Supplement, Olive Oil
Drug
Lead sponsor
Asbell, Penny, M.D.
Individual
Eligibility
18 Years to 90 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2012 · Synced Oct 10, 2026, 8:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Influence of Oral Probiotics on the Microbiome and Lipidome

NCT03605108
View directory record Official record
Conditions
Gut Microbiome, Skin Microbiome, Gut Lipidome, Skin Lipidome, Blood Lipidome
Interventions
Probiotic, Placebo
Dietary Supplement · Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 12, 2019 · Synced Oct 10, 2026, 8:24 PM EDT
Not listed Not applicable Interventional

C15:0 Supplementation in Young Adults at Risk for Metabolic Syndrome

NCT04947176
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Supplement, Placebo
Dietary Supplement · Other
Lead sponsor
Jeffrey B. Schwimmer, MD
Other
Eligibility
18 Years to 25 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Oct 10, 2026, 8:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating the Effects of Cocoa Flavanol on Cognition Assessed Online

NCT04582617
View directory record Official record
Conditions
Aging, Cognitive Change
Interventions
Cocoa Extract, Cocoa Extract Placebo, Multivitamin, Multivitamin placebo
Dietary Supplement
Lead sponsor
Columbia University
Other
Eligibility
65 Years and older
Enrollment
3,959 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2023 · Synced Oct 10, 2026, 8:24 PM EDT
Completed Not applicable Interventional

A Study to Evaluate the Effects of a Prebiotic and Probiotic Supplement to Provide Relief From Symptoms Associated With Bacterial Vaginosis and Yeast Infections.

NCT06665126
View directory record Official record
Conditions
Bacterial Vaginosis, Yeast Infection
Interventions
Prebiotic + Probiotic Supplement, Active Placebo Supplement, Excipient Placebo Supplement
Dietary Supplement
Lead sponsor
Happy V
Industry
Eligibility
25 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 10, 2026, 8:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of a Commercially Available Synbiotic on the Gut Microbiome and Cardiometabolic Health

NCT07515443
View directory record Official record
Conditions
Hypertension, Gut Dysbiosis, Overweight , Obesity
Interventions
Synbiotic, Placebo
Dietary Supplement
Lead sponsor
Southern Utah University
Other
Eligibility
18 Years to 60 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Cedar, Utah
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 10, 2026, 8:24 PM EDT
Completed Phase 1 Interventional

Effect of Fish Oil and Vitamin C on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma

NCT01057615
View directory record Official record
Conditions
Asthma
Interventions
Fish Oil, Ascorbic Acid, Fish Oil Placebo, Ascorbic Acid Placebo
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 31, 2011 · Synced Oct 10, 2026, 8:24 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Oxybutynin and Omega-3 for OAB (Overactive Bladder)

NCT02070042
View directory record Official record
Conditions
Overactive Bladder
Interventions
Omega 3 Fatty Acid, Placebo
Drug
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 31, 2018 · Synced Oct 10, 2026, 8:24 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Fish Oil to Reduce Tobacco Use iN Expectant Mothers Study

NCT03077724
View directory record Official record
Conditions
Tobacco Use in Childbirth, Smoking Cessation, Pregnancy Related
Interventions
Fish oil, Placebos
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Oct 10, 2026, 8:24 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Symbiotic Use in Post-Bariatric Surgery Patients

NCT06252558
View directory record Official record
Conditions
Bariatric Surgery Candidate
Interventions
Symbiotic, Placebo
Dietary Supplement
Lead sponsor
University of North Florida
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 9, 2024 · Synced Oct 10, 2026, 8:24 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Gut Microbiome Response to Long-Haul Travel in Elite Football Players

NCT07585474
View directory record Official record
Conditions
Microbial Composition, Immune Function
Interventions
Probiotic Capsule, Placebo
Drug
Lead sponsor
Sheffield Hallam University
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 10, 2026, 8:24 PM EDT
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers

Trenev Trio/Healthy Trinity for Symptoms of Diarrhea-predominant Irritable Bowel Syndrome (IBS) and Functional Dyspepsia

NCT01268618
View directory record Official record
Conditions
IBS-D and Functional Dyspepsia
Interventions
Probiotic, Placebo
Dietary Supplement
Lead sponsor
Sprim Advanced Life Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
2
States / cities
Duluth, Georgia • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 21, 2011 · Synced Oct 10, 2026, 8:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health

NCT07760506
View directory record Official record
Conditions
Healthy Aging, Inflammaging, Metabolic Health, Quercetin, Coenzyme Q10
Interventions
Quercetin (dietary supplement), Coenzyme Q10, Rice Flour
Dietary Supplement
Lead sponsor
Applied Science & Performance Institute
Industry
Eligibility
50 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 10, 2026, 8:24 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

"CHANGE COVID-19 Severity"

NCT04941703
View directory record Official record
Conditions
COVID-19 Infection
Interventions
Magnesium Citrate plus probiotic
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Oct 10, 2026, 8:24 PM EDT
Active, not recruiting Phase 3 Interventional

FRIEND: Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A Natural CompounD in Green Tea

NCT05364008
View directory record Official record
Conditions
Leiomyoma, Uterine
Interventions
Green Tea Extract, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
4
States / cities
New Haven, Connecticut • Chicago, Illinois • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 10, 2026, 8:24 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Abuse Potential of Orally Administered Crushed Embeda Compared to Crushed Controlled-Release Morphine and Placebo in Non-Dependent Recreational Opioid Users

NCT01380093
View directory record Official record
Conditions
Nondependent Opioid Abuse, Episodic
Interventions
Placebo, MS Contin (morphine sulfate, controlled release), EMBEDA (morphine sulfate / naltrexone hydrochloride)
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 31, 2012 · Synced Oct 10, 2026, 8:24 PM EDT
Recruiting Phase 2 Interventional

Influence of β-hydroxy β-methyl Butyrate (HMB)Supplementation on Post-operative Muscle Mass and Function in Female Athletes

NCT05869812
View directory record Official record
Conditions
Atrophy
Interventions
CaHMB (Dietary supplement, not Drug), CaLa
Drug · Dietary Supplement
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 10, 2026, 8:24 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Clinical Trial Evaluating the Viability of L. Casei + Fish Oil Capsules

NCT01464814
View directory record Official record
Conditions
Signs and Symptoms, Digestive
Interventions
probiotic plus fish oil capsule, Fish oil capsule
Dietary Supplement
Lead sponsor
Nutrition 21, Inc.
Industry
Eligibility
21 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Pembroke Pines, Florida
Source: ClinicalTrials.gov public record
Updated Nov 16, 2011 · Synced Oct 10, 2026, 8:24 PM EDT
Completed Not applicable Interventional

REGAIN: RCT of Oxaloacetate for Fatigue in Long COVID

NCT05840237
View directory record Official record
Conditions
Post-COVID-19 Syndrome, Fatigue Syndrome, Chronic
Interventions
Anhydrous Enol-Oxaloacetate, a "Medical Food", White Rice Flour
Other
Lead sponsor
Terra Biological LLC
Industry
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Oct 10, 2026, 8:24 PM EDT
Completed Phase 4 Interventional Results available

Probiotics to Promote Intestinal Health

NCT02046512
View directory record Official record
Conditions
Communicable Diseases, Infection, Anti-Infective Agents, Therapeutic Uses, Pharmacologic Actions
Interventions
Probiotic, Placebo
Dietary Supplement · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Oct 10, 2026, 8:24 PM EDT
Not yet recruiting Phase 4 Interventional

Impact of Probiotics on Gut Microbiome During Antibiotic Prophylaxis in Elective Orthopedic Surgery

NCT06791993
View directory record Official record
Conditions
Dysbiosis, Gut -microbiota, Microbiome Analysis, Probiotic, Antibiotic Prophylaxis
Interventions
Placebo Capsule, Probiotic with Human Milk Oligosaccharides (HMO)
Drug · Dietary Supplement
Lead sponsor
Acibadem Maslak Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 24, 2025 · Synced Oct 10, 2026, 8:24 PM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

L. Acidophilus (Strain TW01) on Gut Health, Body Composition, and Inflammation

NCT06912100
View directory record Official record
Conditions
Overweight (BMI > 25), Obese, Otherwise Healthy Volunteers
Interventions
Placebo, Probiotic
Dietary Supplement
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 10, 2026, 8:24 PM EDT